Review by : Kretschmer V.
The article gives data on transfusion reactions that are not conclusive. There is no doubt about the reduction of non-hemolytic transfusion reactions in chronically transfused patients when using leukodepleted cellular blood components. Finding no difference in the incidence of transfusion reactions between leukodepleted and non-leukodepleted RBCs is contrary to daily experience. However, it is true that universal leukodepletion does not reduce transfusion reactions as significantly as directed leukodepletion (chronically transfused patients, patients with a history of transfusion reactions, etc.).
– V. Kretschmer.