EDT Time zone (UTC -4)
Exploring Sarcopenia and Cachexia: Multidisciplinary Perspectives
Welcome to the first day of our Annual Conference on Sarcopenia, Cachexia, and Wasting Disorders. Discover world-renowned experts to discuss the latest research and advancements in the field.
CANCER CACHEXIA
9:30-10:30
HALL A
Session A: Abnormal metabolism in cachexia
Chair: Erin Talbert, USA
New insights on the role of purine metabolism in age- and cancer-induced muscle atrophy
Andrea Bonetto, USA
Metabolic crosstalk mechanisms in cancer cachexia
Maria Rohm, Germany
cAMP/CREB1-derived mitochondrial dysfunctions in cachexia
Andrea Graziani, Italy
Causal mechanisms in the mouse model of cancer cachexia – Lewis Lung Carcinoma
Xavier Clemente-Casares, Canada
Chairs & Speakers
Stefan Anker, Germany
Vickie Baracos, Germany
GENERAL SARCOPENIA
10:45-11:45
HALL A
Session B: New findings on muscle wasting
Chair: Simon Wing, Canada
Identifying Mytho as a new regulator of muscle autophagy
Sabbah Hussain, Canada
EDA2R-NIK signaling promotes muscle atrophy linked to cancer cachexia
Serkan Kir, Turkey
Regulation of muscle sarcomere assembly and bioenergetics by an unsuspected E3 ligase: Implications for the diagnostics of myopathies
Jorge Ruas, USA
GLP-2 treatment improves muscle recovery following starvation in rats: a clinical opportunity to reverse muscle wasting?
Didier Attaix, France
Chairs & Speakers
BREAK
12:00-12:50
Lunch Break
Opening Session
13:00-14:10
HALL A
Session C: Opening Session
Welcome
Stefan Anker, Germany
“Prometheus” basic science key note lecture:
Evolution of Cachexia – Adaptive to Maladaptive
Teresa Zimmers, USA
“Hippocrates” clinical science key note lecture:
Integrate the power of preventive nutrition, (p)rehabilitation and positive psychology into cancer cachexia management
Florian Strasser, Switzerland
JCSM & SCWD lecture
Stephan von Haehling, Germany
Stefan Anker, Germany
Chairs & Speakers
Coffee Break
14:10-14:30
MECHANISMS, DIAGNOSTICS
Session D
14:30-15:45
Advances on the roles of cancer-released extracellular vesicles in cachexia
Chairs: James Carson, USA & Denis Guttridge, USA
Cancer-cell-secreted extracellular vesicles dysregulate proteolysis and mitochondrial function in skeletal muscle
Shizhen (Emily) Wang, USA
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Suresh Mathivanan, Australia
The role of tumor-derived extracellular vesicles in white and brown adipose tissue in cachexia
Wei Yan, China
Chemotherapy drugs 5-FU and cisplatin promote cachexia by stimulating extracellular vesicle release from cancer
Yi-Ping Li, USA
Chairs & Speakers
CANCER CACHEXIA
Session E
14:30-15:45
Understanding dysregulated metabolic homeostasis in cancer cachexia
Chair: Steven Heymsfield, USA
Tumor-induced physiological changes in the host in cachexia
Eileen White, USA
Sustained tissue glucose consumption despite reduced food intake in cancer cachexia
Sheng Tony Hui, USA
Imaging metabolic adaptions in cancer cachexia using positron emission tomography (PET)
David Lewis, UK
Improving insulin sensitivity to treat cancer cachexia in humans
Justin Brown, USA
Chairs & Speakers
Coffee Break
15:45-16:45
POSTER SESSION
Poster Session 1
15:50-16:40
Chairs
ABSTRACT SESSION
Rapid Fire Abstracts Session 1
15:50-16:40
Chairs
16:45-18:00
NUTRITION
Session F
Nutrition and translational cachexia research
Chairs: Steven Olde Damink, The Netherlands & Stephan von Haehling, Germany
Nutritional treatment options in cancer care
Paula Ravasco, Portugal
Microbiota and nutrition in oncology: new player?
Carolina Trabulo, Portugal
Balanced nutrition to prevent proetin-energy wasting and preseve renal function in chronic kidney diesease
Kamyar Kalantar-Zadeh, USA
Uncoupling chronic cardiac wasting-associated cardiomyopathy from tumor and skeletal muscle wasting in cancer cachexia
Joseph Metzger, USA
Chairs & Speakers
GENERAL SARCOPENIA
Session G
Body composition changes induced by GLP1-RA in obesity therapy
Chairs: Andrew Coats, Australia & Jennifer Linge, Sweden
The GLP1-RA evidence base for clinical benefits in obesity
Javed Butler, USA
How do GLP1-RA cause weight loss?
Henning Langer, Germany
The use of muscle selective anabolics to make GLP-1 RA weight loss drugs more effective and precise
Mitchell Steiner, USA
Body composition changes when giving GLP1-RA
Stefan Anker, Germany
Anabolic co-treatment in obesity therapy: rationale and early data
David Glass, USA
Panel discussion
Chairs & Speakers
18:30 – 19:30: Welcome Reception - Poster Area
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Embrace this opportunity to redefine the field and create lasting impact in the lives of patients worldwide.
Day 2: Saturday, 7 December 2024
Comprehensive Exploration of Cancer Cachexia and Aging-Related Sarcopenia
Discover the second day of our programme, dedicated to exploring the complexities of cancer cachexia and aging-related sarcopenia. With a stellar lineup of international experts presenting their latest research and engaging in insightful panel discussions
CAREER CAFÉ
08:00-08:50
Ken Fearon Career Café
09:00-10:15
GENERAL CACHEXIA
Session H
Multimodal interventions for cachexia
Chairs: Kam Kalantar Zadeh, USA & Robert Mak, USA
Multimodal interventions in cancer and heart failure cachexia
Masaaki Konishi, Japan
Multi-Modal Integrated Exercise, Anti-inflammatory and Dietary counselling (MMIEAD) for kidney cachexia: Protocol for a cRCT
Joanne Reid, UK
Update on nutrition and exercise interventions in renal cachexia
Adrian Slee, UK
The clinical provision of a multi-disciplinary clinic for heart failure cachexia
Agata Bielecka-Dabrowa, Poland
Chairs & Speakers
CANCER CACHEXIA
Session I
Treatment-induced muscle deficits in cachexia
Chairs: Andrea Bonetto, USA & Paola Costelli, Italy
Mechanisms of radiation-induced muscle fibrosis
Michael De Lisio, Canada
Immune cell signature in chemotherapy-induced cachexia
Brandon VanderVeen, USA
Sex dependent effects in chemotherapy-induced cachexia
Nicholas Greene, USA
Musculoskeletal consequences of pediatric radiotherapy
Joe Chakkalakal, USA
Chairs & Speakers
Coffee Break
10:15-11:15
POSTER SESSION
Poster Session 2
10:20-11:10
Chairs