๐ค Authors: Linxin Yang, Han Wu, Jing Chen, Wei Wang, Zhenxiu Zhang, Jiaping Feng, Wanbing Qiu, Fajin Dong, Ning Lin, Fengyi Yuan
Muscle oxygen saturation stratification by photoacoustic imaging in diabetic sarcopenia: Association with disease status.
Sarcopenia, commonly observed in diabetes, is characterized by reduced muscle mass and function. However, the relationship between muscle oxygen saturation (SOโ) and sarcopenia remains unclear.
Photoacoustic imaging (PAI) offers a promising method for assessment. This study aimed to evaluate SOโ distribution in diabetic sarcopenic patients using PAI and explore associations with clinical parameters.
Type 2 diabetes patients (โฅ 10 years) underwent PAI of the gastrocnemius and vastus lateralis muscles. Sarcopenia was diagnosed by AWGS 2019/2020 criteria.
SOโ values stratified patients into hypoxia, intermediate, and hyperoxia groups. The study included 64 sarcopenic and 115 non-sarcopenic patients.
Mean SOโ was significantly lower in sarcopenia (63.28โฏ% vs. 66.26โฏ%, Pโฏ<โฏ0.001). PAI-measured SOโ was an independent protective factor (ฮฒ = -0.10, Pโฏ=โฏ0.001).
In conclusion, PAI-assessed SOโ is associated with sarcopenia and may serve as an early screening biomarker.
