A probiotic Bifidobacterium pseudocatenulatum converts hesperidin to bioactive hesperetin and improves metabolic dysfunction in aging mice.
Dietary flavonoids often require microbial metabolism to generate bioactive metabolites that influence host physiology. Hesperidin, a citrus flavanone glycoside, exhibits limited intestinal absorption and depends on gut microbial biotransformation to yield its active aglycone, hesperetin. Hesperetin activates CDGSH iron-sulfur domain...
🗓️ 2026-09-23
📰 Publication: Gut Microbes
Read MoreA probiotic Bifidobacterium pseudocatenulatum converts hesperidin to bioactive hesperetin and improves metabolic dysfunction in aging mice.