Child

Inter-tissue relationships of gene expression in liver, muscle and adipose tissue of children with end-stage chronic liver disease.

OBJECTIVES

End-stage chronic liver disease in children is associated with sarcopenia and aberrant adipose tissue mass. We investigated correlations between liver pathology-associated gene pathways (fibrosis, inflammation and steatosis) and metabolic genes in muscle and adipose tissue.

METHODS

Liver, rectus abdominis muscle and subcutaneous...

🗓️ 2026-07-06
📰 Publication: Journal Of Pediatric Gastroenterology And Nutrition
Read MoreInter-tissue relationships of gene expression in liver, muscle and adipose tissue of children with end-stage chronic liver disease.

Handgrip Strength Thresholds to Detect Cardiometabolic Risk in Youth: Cross-Sectional Study and Meta-Analysis.

BACKGROUND

Muscular fitness, particularly handgrip strength, is increasingly recognized as a robust marker of cardiometabolic risk (CMR) in children and adolescents. However, evidence-based diagnostic thresholds for identifying at-risk individuals remain scarce, particularly in children. This study aimed to (1) establish sex-specific...

🗓️ 2026-05-28
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreHandgrip Strength Thresholds to Detect Cardiometabolic Risk in Youth: Cross-Sectional Study and Meta-Analysis.

Sarcopenic Obesity in Children: An Emerging Complication Evidenced by Clinical Data and a Juvenile Mouse Model.

BACKGROUND

Sarcopenic obesity (SO) is well-characterized in older adults, but its impact on muscle development in children remains poorly understood. This study investigated the effects of childhood obesity on musculoskeletal health and the underlying mechanisms.

METHODS

We enrolled 1447 children (31.4% girls; median...

🗓️ 2026-04-17
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreSarcopenic Obesity in Children: An Emerging Complication Evidenced by Clinical Data and a Juvenile Mouse Model.

Management of Children Awaiting Liver Transplantation: Sarcopenia, Cholestasis and Beyond.

Sarcopenia has been increasingly recognized as a risk factor for worse outcomes in liver transplantation; however, the data remain limited on pediatric-specific outcomes. These gaps in knowledge are in part due to the lack of a standardized definition, challenges inherent...

🗓️ 2025-11-01
📰 Publication: Pediatric Transplantation
Read MoreManagement of Children Awaiting Liver Transplantation: Sarcopenia, Cholestasis and Beyond.

Sarcopenia in Children Post Liver Transplant: Development of a Home-Based Video Program to Support Muscle Strength and Function-A Pre-Post Controlled Pilot Study.

Sarcopenia is common in children after liver transplantation (LTx). Resistance training (RT) may be effective in combating sarcopenia. The purpose of the study was to test the feasibility and impact of a 12-week RT program on skeletal muscle mass (SMM),...

🗓️ 2024-09-01
📰 Publication: Clinical Transplantation
Read MoreSarcopenia in Children Post Liver Transplant: Development of a Home-Based Video Program to Support Muscle Strength and Function-A Pre-Post Controlled Pilot Study.

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