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Adiposetissue

Unveiling Adipose Tissue: From Energy Storage to Hormonal Regulation. Embark on a deep dive into adipose tissue, the body’s complex fat storage system. Learn about its dual role in energy storage and hormonal regulation, and explore the latest research shedding light on white and brown adipose tissue functions.

The BET inhibitor JQ1 targets fat metabolism and counteracts obesity.

Obesity, one of the most frequent health problems in the adult population, is a condition characterized by excessive white adipose tissue accumulation and accompanied by the increased risk to develop other disorders such as type II diabetes, cardiovascular disorders, physical...
πŸ—“οΈ 2024-02-15
πŸ“° Publication: Journal Of Advanced Research
Read MoreThe BET inhibitor JQ1 targets fat metabolism and counteracts obesity.

Skeletal muscle and visceral adipose radiodensities are pre-surgical, non-invasive markers of aggressive kidney cancer.

Most studies on body composition in kidney cancer have been conducted among patients with metastatic disease. Given that aggressive tumours can adversely impact body composition and even non-metastatic tumours can be aggressive, we evaluated associations between pre-surgical body composition features...
πŸ—“οΈ 2024-01-24
πŸ“° Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreSkeletal muscle and visceral adipose radiodensities are pre-surgical, non-invasive markers of aggressive kidney cancer.

Assessment of lipolysis biomarkers in adipose tissue of patients with gastrointestinal cancer.

Adipose tissue metabolism may be impaired in patients with cancer. In particular, increased lipolysis was described in cancer-promoting adipose tissue atrophy. For this reason, we assessed the expression of the lipolysis-associated genes and proteins in subcutaneous adipose tissue (SAT) of...
πŸ—“οΈ 2024-01-02
Read MoreAssessment of lipolysis biomarkers in adipose tissue of patients with gastrointestinal cancer.

Body composition and lung cancer-associated cachexia in TRACERx.

Cancer-associated cachexia (CAC) is a major contributor to morbidity and mortality in individuals with non-small cell lung cancer. Key features of CAC include alterations in body composition and body weight. Here, we explore the association between body composition and body...
πŸ—“οΈ 2023-04-12
πŸ“° Publication: Nat Med
Read MoreBody composition and lung cancer-associated cachexia in TRACERx.

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