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Cancer-associatedcachexia

Defining and Addressing Research Priorities in Cancer Cachexia through Transdisciplinary Collaboration.

For many patients, the cancer continuum includes a syndrome known as cancer-associated cachexia (CAC), which encompasses the unintended loss of body weight and muscle mass, and is often associated with fat loss, decreased appetite, lower tolerance and poorer response to...
🗓️ 2024-06-27
Read MoreDefining and Addressing Research Priorities in Cancer Cachexia through Transdisciplinary Collaboration.

Skeletal Muscle Proteome Modifications following Antibiotic-Induced Microbial Disturbances in Cancer Cachexia.

Cancer cachexia is an involuntary loss of body weight, mostly of skeletal muscle. Previous research favors the existence of a microbiota-muscle crosstalk, so the aim of the study was to evaluate the impact of microbiota alterations induced by antibiotics on...
🗓️ 2024-06-19
📰 Publication: Journal Of Proteome Research
Read MoreSkeletal Muscle Proteome Modifications following Antibiotic-Induced Microbial Disturbances in Cancer Cachexia.

Targeted nutritional intervention attenuates experimental lung cancer cachexia.

Cachexia, a syndrome with high prevalence in non-small cell lung cancer patients, impairs quality of life and reduces tolerance and responsiveness to cancer therapy resulting in decreased survival. Optimal nutritional care is pivotal in the treatment of cachexia and a...
🗓️ 2024-07-04
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreTargeted nutritional intervention attenuates experimental lung cancer cachexia.

KLF10: a point of convergence in cancer cachexia.

Cancer-associated cachexia is a wasting syndrome entailing loss in body mass and a shortened life expectancy. There is currently no effective treatment to abrogate this syndrome, which leads to 20-30% of deaths in patients with cancer. While there have been...
🗓️ 2024-07-15
📰 Publication: Current Opinion In Supportive And Palliative Care
Read MoreKLF10: a point of convergence in cancer cachexia.

The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia.

With limited treatment options, cachexia remains a major challenge for patients with cancer. Characterizing the interplay between tumor cells and the immune microenvironment may help identify potential therapeutic targets for cancer cachexia. Herein, we investigate the critical role of macrophages...
🗓️ 2024-03-29
📰 Publication: Cancer Cell
Read MoreThe crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia.

Polymorphism (rs1143634) and IL-1β Plasma Concentration as Predictors of Nutritional Disorders and Prognostic Factors in Multiple Myeloma Patients.

Multiple myeloma (MM) is a hematological neoplasm of the early precursor of B-cells. The most characteristic symptoms observed during MM include hypocalcemia, anemia, bacterial infections, and renal damage. Nutritional disorders, especially malnutrition, are noted in about 35-71% of MM patients....
🗓️ 2024-03-24
Read MorePolymorphism (rs1143634) and IL-1β Plasma Concentration as Predictors of Nutritional Disorders and Prognostic Factors in Multiple Myeloma Patients.

Cancer cachexia: biomarkers and the influence of age.

Cancer cachexia (Ccx) is a complex metabolic condition characterized by pronounced muscle and fat wasting, systemic inflammation, weakness and fatigue. Up to 30% of cancer patients succumb directly to Ccx, yet therapies that effectively address this perturbed metabolic state are...
🗓️ 2024-02-27
📰 Publication: Molecular Oncology
Read MoreCancer cachexia: biomarkers and the influence of age.

Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series.

There is no consensus on the optimal endpoint(s) in cancer cachexia trials. Endpoint variation is an obstacle when comparing interventions and their clinical value. The aim of this systematic review was to summarize and evaluate endpoints used to assess appetite...
🗓️ 2024-02-11
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreAppetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series.

Quality of life endpoints in cancer cachexia clinical trials: Systematic review 3 of the cachexia endpoints series.

The use of patient-reported outcomes (PROMs) of quality of life (QOL) is common in cachexia trials. Patients' self-report on health, functioning, wellbeing, and perceptions of care, represent important measures of efficacy. This review describes the frequency, variety, and reporting of...
🗓️ 2024-03-29
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreQuality of life endpoints in cancer cachexia clinical trials: Systematic review 3 of the cachexia endpoints series.

The role of the nurse in meeting the educational needs for self-care in cachectic cancer patients and their family caregivers: A scoping review.

To give an overview of what is known about the nurse contribution to education in self-care by people with cancer cachexia and their family caregivers. Nurse-led patient education can help patients and their family caregivers to manage cancer symptoms, cancer...
🗓️ 2023-08-23
Read MoreThe role of the nurse in meeting the educational needs for self-care in cachectic cancer patients and their family caregivers: A scoping review.

Holistic multimodal care for patients with cancer cachexia and their family caregivers.

Patients with cancer cachexia frequently suffer from physical symptoms and psychological symptoms of illness, which can lead to emotional distress in patients and family caregivers. Although there is no standard care to manage cancer cachexia despite its high prevalence and...
🗓️ 2023-08-06
Read MoreHolistic multimodal care for patients with cancer cachexia and their family caregivers.

Factors associated with multimodal care practices for cancer cachexia among registered dietitians.

This study aimed to determine factors associated with multimodal care practices for cancer cachexia among registered dietitians (RDs) working in cancer care. A secondary analysis was performed using RDs' data. Data on knowledge, skills, and confidence in multimodal care were...
🗓️ 2024-03-06
📰 Publication: Supportive Care In Cancer
Read MoreFactors associated with multimodal care practices for cancer cachexia among registered dietitians.

Fluid retention and weight loss in refractory cancer cachexia.

It is unknown to what extent the fluid retention (FR) status disrupts the detection of weight loss rate (WLR) in adult patients with advanced cancer. This study aimed to determine the association of FR status with WLR. This study was...
🗓️ 2024-02-23
📰 Publication: Bmj Supportive & Palliative Care
Read MoreFluid retention and weight loss in refractory cancer cachexia.

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