REGISTER FOR THE 2025 CONFERENCE

The Society
Conference and Events
- Conferences
  
  Annual Conference 2025
  
  Abstract Submission 2025
  
  Programme 2025
  
  Congress Information 2025
  
  Register for the Conference ⟶
  
  Join us at the forefront of innovation and collaboration! Secure your spot at the 2025 conference today. Don’t miss this opportunity to connect with industry leaders, engage in insightful discussions, and expand your professional network.
  
  Submit an Abstract 2025
  Are you ready to share your groundbreaking research and innovative ideas with leading experts in the field? We invite you to submit your abstract for the 2025 conference.
Resources
- Resources
  
  Latest ↗
  
  Cachexia ↗
  
  Sarcopenia ↗
  
  Muscle Wasting ↗
  
  Frailty ↗
  
  Ageing ↗
  
  Nutrition ↗
  
  From the Literature ↗
  
  Cancer Cachexia
  
  Exercise ↗
  
  Videos ↗
  
  Explore our Publications Digest ⟶
  
  Staying informed on the latest in cachexia, sarcopenia, and wasting disorders research is essential yet challenging. The SCWD Digest offers concise updates and expert insights into significant studies and developments.
  
  The Journal of Cachexia, Sarcopenia & Muscle ⟶
  The Journal of Cachexia, Sarcopenia and Muscle is a peer-reviewed international journal dedicated to publishing both research and clinical materials related to cachexia and sarcopenia from all fields of the life sciences.
Guidelines
Membership

Research

Muscle

Soyasapogenol B prevents sarcopenia by increasing skeletal muscle mass and function through the Sirt1/PGC-1α and PI3K pathway.

Sarcopenia, caused by aging, is characterized by the reduction of muscle mass and function. In this study, we investigated the effects of soyasapogenol B on skeletal muscle and the underlying mechanisms to determine its potential as a prevention for sarcopenia....

🗓️ 2025-07-05

📰 Publication: Biomedicine & Pharmacotherapy

Drug_therapy / Mitochondria / Muscle,_skeletal / muscles / Organelle_biogenesis / Research / Sarcopenia / Sirtuin_1

Muscle

Clarification and standardization of dual-energy X-ray absorptiometry terminology for accurate scientific communication and clinical diagnostic accuracy.

The evaluation of skeletal muscle (SM) mass has significant clinical and research relevance in the diagnosis and management of conditions such as malnutrition, sarcopenia, sarcopenic obesity, and cancer cachexia. Dual-energy X-ray absorptiometry (DXA) is now the most widely used method...

🗓️ 2025-06-30

📰 Publication: American Journal Of Clinical Nutrition

Body_composition / Communication / Muscle,_skeletal / muscles / Research / Sarcopenia

Muscle

Sarcopenia in Parkinson's disease: From pathogenesis to interventions.

Parkinson's disease (PD) and sarcopenia are prevalent age-related conditions that often coexist in affected individuals. Sarcopenia is particularly common among PD patients, with severe cases affecting approximately one in five individuals with the disease. Furthermore, sarcopenia is closely linked to...

🗓️ 2025-04-19

📰 Publication: Metabolism-Clinical And Experimental

muscles / Parkinson_disease / Research / Sarcopenia / therapeutics

Muscle

A Novel Research Paradigm for Sarcopenia of Limb Muscles: Lessons From the Perpetually Working Diaphragm's Anti-Aging Mechanisms.

Skeletal muscle function and mass continuously decrease during aging. Most studies target limb muscles owing to their direct impact on mobility and falls risk. The diaphragm (DIA), also a type of skeletal muscle with different phenotype, has received less attention....

🗓️ 2025-04-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Aging / cachexia / Diaphragm / Genes / Lung / muscles / Research / Running / Sarcopenia / Spermine / Transcriptome / Vital_capacity

Exercise

Multimodal interventions for cachexia management.

Cachexia (disease-related wasting) is a complex metabolic syndrome which occurs in people with chronic illnesses, including cancer, HIV/AIDS, kidney disease, heart disease, and chronic obstructive pulmonary disease (COPD). People with cachexia experience unintentional weight loss, muscle loss, fatigue, loss of...

🗓️ 2025-03-25

📰 Publication: Cochrane Database Of Systematic Reviews

Aftercare / Appetite / Bias / Body_composition / cachexia / Chronic_disease / Drug-related_side_effects_and_adverse_reactions / FATIGUE / Heart_diseases / Kidney / Kidney_diseases / neoplasms / Pulmonary_disease,_chronic_obstructive / Quality_of_life / Research / therapeutics

Muscle

Causal relationships of circulating amino acids with sarcopenia-related traits: A bidirectional Mendelian randomization study.

Recent studies have indicated a correlation between certain Amino acids (AAs) and sarcopenia. However, the exact causal relationship among these associations is still unclear. This study aims to elucidate the causal relationships between 20 types of AAs and the phenotypic...

🗓️ 2025-02-28

📰 Publication: Clinical Nutrition

Amino_acids / Enteral_nutrition / muscles / Parenteral_nutrition / Polymorphism,_single_nucleotide / Random_allocation / Research / Sarcopenia

Muscle

Detrimental Effects of β2-Microglobulin on Muscle Metabolism: Evidence From In Vitro, Animal and Human Research.

β2-Microglobulin (B2M) has garnered considerable interest as a potential pro-ageing factor, leading to speculation about its involvement in muscle metabolism and the development of sarcopenia, a key component of ageing phenotypes. To explore this hypothesis, we conducted a comprehensive investigation...

🗓️ 2025-04-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Biomarkers / BLOOD / cachexia / Gait / Hand_strength / muscles / Phenotype / Research / Sarcopenia / SERUM / Walking_speed

Muscle

Selpercatinib mitigates cancer cachexia independent of anti-tumor activity in the HT1080 tumor model.

Anorexia is a major cause of cancer cachexia and is induced by growth differentiation factor-15 (GDF15), which activates the rearranged during transfection (RET) protein tyrosine kinase in the hindbrain through GDF family receptor α-like (GFRAL), raising the possibility of targeting...

🗓️ 2025-01-06

📰 Publication: Cancer Letters

cachexia / Cancer-associated_cachexia / Genes / Growth / Muscle,_skeletal / muscles / neoplasms / Protein-tyrosine_kinases / Research / Weight_gain

Cachexia

Prevalence and Prognostic Significance of Sarcopenia in Gynecologic Oncology: A Systematic Review and Meta-Analysis.

Sarcopenia in gynaecologic oncology patients has garnered increasing attention, but its prevalence has not been comprehensively summarized. This study aims to integrate the prevalence of sarcopenia in this population through systematic evaluation and meta-analysis, providing a reference for future clinical...

🗓️ 2025-02-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Bias / neoplasms / PREVALENCE / Prognosis / Research / Sarcopenia

Muscle

Exploring opportunities to better characterize the effects of dietary protein on health across the lifespan.

Remarkable advances have been made over the last thirty years in understanding the role of dietary protein in optimizing muscle health across the lifespan. That is, acute (<24h) stable isotope-derived measures of muscle protein synthesis have led to established recommendations...

🗓️ 2024-11-26

Cardiovascular_diseases / Diabetes_mellitus / Diabetes_mellitus,_type_2 / Dietary_proteins / muscles / Obesity / Research / Sarcopenia / Sleep

Cachexia

The lived experience of renal cachexia: An interpretive phenomenological analysis.

Chronic kidney disease is common, affecting up to 13 % of the global population, and is predicted to become the fifth leading cause of 'life years lost' by 2040. Individuals with end-stage kidney disease commonly develop complications such as protein-energy...

🗓️ 2024-08-22

Caregivers / Kidney / Kidney_diseases / Kidney_failure,_chronic / Research

Cachexia

Ubiquitylomics: An Emerging Approach for Profiling Protein Ubiquitylation in Skeletal Muscle.

Skeletal muscle is a highly adaptable tissue, finely tuned by various physiological and pathological factors. Whilst the pivotal role of skeletal muscle in overall health is widely acknowledged, unravelling the underlying molecular mechanisms poses ongoing challenges. Protein ubiquitylation, a crucial...

🗓️ 2024-09-16

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Muscle,Skeletal / muscles / Proteinprocessing,post-translational / Proteomics / Research / Sarcopenia / Ubiquitin / Ubiquitination

Cachexia

Defining and Addressing Research Priorities in Cancer Cachexia through Transdisciplinary Collaboration.

For many patients, the cancer continuum includes a syndrome known as cancer-associated cachexia (CAC), which encompasses the unintended loss of body weight and muscle mass, and is often associated with fat loss, decreased appetite, lower tolerance and poorer response to...

🗓️ 2024-06-27

Biomarkers / bodycomposition / Cancer-associatedcachexia / EXERCISE / Machinelearning / neoplasms / Research / therapeutics

Cachexia

Quality of life endpoints in cancer cachexia clinical trials: Systematic review 3 of the cachexia endpoints series.

The use of patient-reported outcomes (PROMs) of quality of life (QOL) is common in cachexia trials. Patients' self-report on health, functioning, wellbeing, and perceptions of care, represent important measures of efficacy. This review describes the frequency, variety, and reporting of...

🗓️ 2024-03-29

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Cancer-associatedcachexia / neoplasms / Qualityoflife / Research / Researchdesign / Sarcopenia

Sarcopenia

Sarcopenia of Ageing: Does a Healthier Lifestyle Matter in Reversing the Trajectory? A Brief Narrative Review and a Call for Action in Saudi Arabia.

The concept of health span is an emerging topic in recent years, with a truly palpable relevance to public health. With ageing comes a loss of skeletal muscle mass, strength, and performance, which is termed as sarcopenia. Sarcopenia is a...

🗓️ 2024-01-15

EXERCISE / Lifestyle / Muscularatrophy / Publichealth / Research

Subscribe to the SCWD Newsletter

Stay Informed with the Latest Updates and Exclusive Insights!