Frailty

Why Osteosarcopenia Matters: Clinical and Investigative Implications.

BACKGROUND

Osteosarcopenia, the combination of osteoporosis and sarcopenia, is a geriatric syndrome linked to functional decline, falls, and fragility fractures. The interaction among bone, muscle, and their shared pathophysiology is driven by mechanical, metabolic, and hormonal factors. With global population aging...

🗓️ 2026-05-15
📰 Publication: European Journal Of Clinical Investigation
Read MoreWhy Osteosarcopenia Matters: Clinical and Investigative Implications.

Home-Based Intervention to Prevent Functional Decline in (Pre)frail Older Adults: The PromeTheus Randomized Controlled Trial.

BACKGROUND

Older adults with (pre)frailty are vulnerable to deteriorations in physical functioning, mobility and independence. Evidence for frailty interventions utilizing existing services within primary healthcare structure is limited. The PromeTheus trial aimed to evaluate the effectiveness of a home-based, multifactorial, interdisciplinary...

🗓️ 2026-05-14
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreHome-Based Intervention to Prevent Functional Decline in (Pre)frail Older Adults: The PromeTheus Randomized Controlled Trial.

HQ1: Do Interventions and Assessments Using Digital Health Services Prevent Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ1: Do Interventions and Assessments Using Digital Health Services Prevent Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ5: Do Intervention and Evaluation Using Digital Health Services Prevent Sarcopenia in High-Risk Non-Older Adults? English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ5: Do Intervention and Evaluation Using Digital Health Services Prevent Sarcopenia in High-Risk Non-Older Adults? English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ2: Do Interventions and Assessments Using Digital Health Services Prevent Frailty in High-Risk Non-Older Adults Who Are at Risk of Frailty?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ2: Do Interventions and Assessments Using Digital Health Services Prevent Frailty in High-Risk Non-Older Adults Who Are at Risk of Frailty?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ7: Does Exercise Prevent the Onset and Progression of Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ7: Does Exercise Prevent the Onset and Progression of Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ4: Do Interventions and Assessments That Use Digital Health Services Prevent Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ4: Do Interventions and Assessments That Use Digital Health Services Prevent Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ11: Does EMS (Electrical Muscle Stimulation) Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ11: Does EMS (Electrical Muscle Stimulation) Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ9: Do Exercise Interventions Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ9: Do Exercise Interventions Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ3: Do Interventions and Assessments Using Digital Health Services Improve Frailty Status in Frail Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ3: Do Interventions and Assessments Using Digital Health Services Improve Frailty Status in Frail Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ10: Do Nutritional Interventions Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ10: Do Nutritional Interventions Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ6: Do Interventions or Assessments Using Digital Health Services Improve Sarcopenia Among Older Adults With Sarcopenia?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ6: Do Interventions or Assessments Using Digital Health Services Improve Sarcopenia Among Older Adults With Sarcopenia?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

Microbes and ageing beyond the gut: the oral microbiome and frailty, sarcopenia and neurocognitive disorders in the elderly – a scoping review protocol.

INTRODUCTION

Population ageing is a global phenomenon that has resulted in an increase in the number of patients with chronic diseases and geriatric syndromes. Frailty, sarcopenia and neurocognitive disorders are among the most prevalent conditions affecting older adults and have a...

🗓️ 2026-01-29
📰 Publication: Bmj Open
Read MoreMicrobes and ageing beyond the gut: the oral microbiome and frailty, sarcopenia and neurocognitive disorders in the elderly – a scoping review protocol.

HQ8: Do Nutritional Interventions Prevent the Onset and Progression of Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-01-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ8: Do Nutritional Interventions Prevent the Onset and Progression of Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

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