Frailty

Assessing the relationships between frailty, sarcopenia and Alzheimer's disease biomarkers: a scoping review.

INTRODUCTION

While both frailty and sarcopenia have been linked with the Alzheimer's disease (AD) clinical phenotype, their association with AD pathophysiology is unclear. This review aimed to identify current evidence of relationships between frailty, sarcopenia and AD biomarkers.

METHODS

Four databases (Ovid MEDLINE,...

🗓️ 2026-07-08
📰 Publication: Ageing Research Reviews
Read MoreAssessing the relationships between frailty, sarcopenia and Alzheimer's disease biomarkers: a scoping review.

Association of Airway Mucus Plugs and Physical Activity, Exercise Tolerance, Sarcopenia, and Frailty in Patients With COPD and Pre-COPD.

BACKGROUND AND OBJECTIVE

Airway mucus plugs on computed tomography (CT) are an imaging biomarker of chronic obstructive pulmonary disease (COPD) associated with airflow limitation, respiratory symptoms, and poor prognosis. However, clinical phenotypes relevant to mucus plugs, including sarcopenia and frailty, are...

🗓️ 2026-06-12
📰 Publication: Respirology
Read MoreAssociation of Airway Mucus Plugs and Physical Activity, Exercise Tolerance, Sarcopenia, and Frailty in Patients With COPD and Pre-COPD.

Artificial intelligence analysis of temporalis muscle thickness for monitoring sarcopenia and clinical outcomes in individuals with paediatric brain tumours: a retrospective cohort study.

BACKGROUND

People with and who have survived paediatric brain tumour (PBT) have a poor quality of life due to physiological frailty, a primary component of which is sarcopenia (ie, low lean muscle mass) and the associated condition, sarcopenic overweight. MRI-based temporalis...

🗓️ 2026-05-28
Read MoreArtificial intelligence analysis of temporalis muscle thickness for monitoring sarcopenia and clinical outcomes in individuals with paediatric brain tumours: a retrospective cohort study.

Why Osteosarcopenia Matters: Clinical and Investigative Implications.

BACKGROUND

Osteosarcopenia, the combination of osteoporosis and sarcopenia, is a geriatric syndrome linked to functional decline, falls, and fragility fractures. The interaction among bone, muscle, and their shared pathophysiology is driven by mechanical, metabolic, and hormonal factors. With global population aging...

🗓️ 2026-05-15
📰 Publication: European Journal Of Clinical Investigation
Read MoreWhy Osteosarcopenia Matters: Clinical and Investigative Implications.

Home-Based Intervention to Prevent Functional Decline in (Pre)frail Older Adults: The PromeTheus Randomized Controlled Trial.

BACKGROUND

Older adults with (pre)frailty are vulnerable to deteriorations in physical functioning, mobility and independence. Evidence for frailty interventions utilizing existing services within primary healthcare structure is limited. The PromeTheus trial aimed to evaluate the effectiveness of a home-based, multifactorial, interdisciplinary...

🗓️ 2026-05-14
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreHome-Based Intervention to Prevent Functional Decline in (Pre)frail Older Adults: The PromeTheus Randomized Controlled Trial.

HQ1: Do Interventions and Assessments Using Digital Health Services Prevent Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ1: Do Interventions and Assessments Using Digital Health Services Prevent Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ5: Do Intervention and Evaluation Using Digital Health Services Prevent Sarcopenia in High-Risk Non-Older Adults? English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ5: Do Intervention and Evaluation Using Digital Health Services Prevent Sarcopenia in High-Risk Non-Older Adults? English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ2: Do Interventions and Assessments Using Digital Health Services Prevent Frailty in High-Risk Non-Older Adults Who Are at Risk of Frailty?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ2: Do Interventions and Assessments Using Digital Health Services Prevent Frailty in High-Risk Non-Older Adults Who Are at Risk of Frailty?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ7: Does Exercise Prevent the Onset and Progression of Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ7: Does Exercise Prevent the Onset and Progression of Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ4: Do Interventions and Assessments That Use Digital Health Services Prevent Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ4: Do Interventions and Assessments That Use Digital Health Services Prevent Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ11: Does EMS (Electrical Muscle Stimulation) Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ11: Does EMS (Electrical Muscle Stimulation) Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ9: Do Exercise Interventions Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ9: Do Exercise Interventions Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ3: Do Interventions and Assessments Using Digital Health Services Improve Frailty Status in Frail Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ3: Do Interventions and Assessments Using Digital Health Services Improve Frailty Status in Frail Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ10: Do Nutritional Interventions Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ10: Do Nutritional Interventions Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

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