Gastrointestinal_diseases

Inter-tissue relationships of gene expression in liver, muscle and adipose tissue of children with end-stage chronic liver disease.

OBJECTIVES

End-stage chronic liver disease in children is associated with sarcopenia and aberrant adipose tissue mass. We investigated correlations between liver pathology-associated gene pathways (fibrosis, inflammation and steatosis) and metabolic genes in muscle and adipose tissue.

METHODS

Liver, rectus abdominis muscle and subcutaneous...

🗓️ 2026-07-06
📰 Publication: Journal Of Pediatric Gastroenterology And Nutrition
Read MoreInter-tissue relationships of gene expression in liver, muscle and adipose tissue of children with end-stage chronic liver disease.

Determinants of Gastrointestinal Disease Burden and Survival in Systemic AL Amyloidosis.

Gastrointestinal (GI) involvement is a clinically relevant but undercharacterized manifestation of systemic light chain amyloidosis (AL). We aimed to define the clinical spectrum, histologic patterns, and outcomes of symptomatic GI involvement in AL. We retrospectively analyzed 4,396 patients with AL...

🗓️ 2026-04-09
📰 Publication: Blood Advances
Read MoreDeterminants of Gastrointestinal Disease Burden and Survival in Systemic AL Amyloidosis.

Impact of sarcopenia and changes in skeletal muscle mass on prognosis of patients with pancreatic ductal adenocarcinoma receiving chemotherapy with first-line gemcitabine and nab-paclitaxel: a prospective study.

Sarcopenia is an important prognostic factor for cancer patients. Here, we prospectively examined the effects of sarcopenia on progression-free survival (PFS) and overall survival (OS) of patients with pancreatic ductal adenocarcinoma (PDAC) treated with first-line gemcitabine and nab-paclitaxel (GnP). This...

🗓️ 2025-07-17
📰 Publication: Journal Of Gastroenterology
Read MoreImpact of sarcopenia and changes in skeletal muscle mass on prognosis of patients with pancreatic ductal adenocarcinoma receiving chemotherapy with first-line gemcitabine and nab-paclitaxel: a prospective study.

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