Functional_status

FcRn function alone cannot account for elevated IgG clearance in the Lewis lung carcinoma model of cancer cachexia.

PURPOSE

The neonatal Fc receptor (FcRn) protects IgG-based monoclonal antibodies (mAbs) from catabolism by direct binding within endosomes and facilitates their recycling to extracellular spaces. Elevated clearance of immune checkpoint inhibitors (ICIs) and other IgG-based mAbs is often observed in patients...

🗓️ 2026-05-09
📰 Publication: International Immunopharmacology
Read MoreFcRn function alone cannot account for elevated IgG clearance in the Lewis lung carcinoma model of cancer cachexia.

Quality of Life of Colorectal Cancer Patients Treated with Chemotherapy.

Background/Objectives: Colorectal cancer (CRC) is associated with anorexia-cachexia syndrome, which negatively affects health-related quality of life (HRQoL). This study aimed to evaluate HRQoL and functional status in CRC patients undergoing chemotherapy who were eligible for oral nutritional supplementation (ONS). Methods:...

🗓️ 2026-01-28
Read MoreQuality of Life of Colorectal Cancer Patients Treated with Chemotherapy.

Association of cachexia with activities of daily living and discharge destinations among inpatients with dysphagia in a convalescent rehabilitation phase; A multi-center cohort study.

Although a recent study reported an association between cachexia, as defined by the Asian Working Group for Cachexia (AWGC), and lower functional recovery at discharge among post-stroke patients capable of oral intake during the convalescent rehabilitation phase, its impact on...

🗓️ 2025-09-30
Read MoreAssociation of cachexia with activities of daily living and discharge destinations among inpatients with dysphagia in a convalescent rehabilitation phase; A multi-center cohort study.

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