Cognition

Do myokines influence the associations between sarcopenia-related parameters and cognitive function in community-dwelling older adults: exploratory results from the ENHANce study.

BACKGROUND

Studies have shown that sarcopenia and its related parameters are associated with cognition. Preclinical evidence suggests that myokines, such as irisin, Brain-Derived Neurotrophic Factor(BDNF), myostatin and Insulin-like Growth Factor-1(IGF-1) might explain this relationship. This study aimed to explore the associations...

🗓️ 2026-01-19
📰 Publication: Experimental Gerontology
Read MoreDo myokines influence the associations between sarcopenia-related parameters and cognitive function in community-dwelling older adults: exploratory results from the ENHANce study.

Public Health.

BACKGROUND

Sarcopenia is associated with an increased risk of cognitive impairment, yet very few studies have examined structural brain changes in sarcopenia. The current study aims to explore cognitive changes and their neuroimaging correlates of individuals with sarcopenia in an urban...

🗓️ 2025-12-23
📰 Publication: Alzheimers & Dementia
Read MorePublic Health.

Exploring the role of intrinsic and extrinsic factors on the associations between sarcopenia and falls in older adults.

The present study investigated the moderating effects of intrinsic and extrinsic factors on the association between sarcopenia and falls in older adults. This prospective cohort study was conducted among octogenarians residing in the mountainous Sirente geographic area of Central Italy....

🗓️ 2025-08-14
📰 Publication: Scientific Reports
Read MoreExploring the role of intrinsic and extrinsic factors on the associations between sarcopenia and falls in older adults.

Moderation Effect of Handgrip Strength on Cognition and Functional Independence Associations in Adults Over 90 Years.

The causal relationship between cognitive impairment and functional decline seems bidirectional in older adults. This study aimed to determine the moderating effect of handgrip strength on the relationship between cognition and functional independence among Brazilian nonagenarians and centenarians. A cross-sectional...

🗓️ 2025-06-01
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreModeration Effect of Handgrip Strength on Cognition and Functional Independence Associations in Adults Over 90 Years.

Enhancing Neurocognitive Health via Activity, Nutrition and Cognitive Exercise (ENHANCE): A Randomized Controlled Trial.

While multidomain interventions show promise for promoting healthy aging, their impact on brain structure remains unclear. This randomized controlled trial (ENHANCE) assessed the efficacy of a 12-month group-based multidomain intervention on brain structure and function in community-dwelling older adults, with...

🗓️ 2025-06-01
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreEnhancing Neurocognitive Health via Activity, Nutrition and Cognitive Exercise (ENHANCE): A Randomized Controlled Trial.

Identification of risk factors and development of a predictive nomogram for sarcopenia in Alzheimer's disease.

Sarcopenia, with its complex diagnostic process, is a likely independent predictor of poor prognosis in patients with Alzheimer's disease (AD). However, research on the clinical characteristics and biomarkers of AD patients with sarcopenia (ADSA) is limited. This study included 180...

🗓️ 2025-01-08
📰 Publication: Alzheimers & Dementia
Read MoreIdentification of risk factors and development of a predictive nomogram for sarcopenia in Alzheimer's disease.

Exploring the mediating roles of depression and cognitive function in the association between sarcopenia and frailty: A Cox survival analysis approach.

Despite earlier research indicating a potential link between the development of sarcopenia and an elevated risk of frailty, the lack of comprehensive prospective data on the correlation between sarcopenia and frailty incidence leaves open the question of whether depression and...

🗓️ 2024-12-17
📰 Publication: Journal Of Advanced Research
Read MoreExploring the mediating roles of depression and cognitive function in the association between sarcopenia and frailty: A Cox survival analysis approach.

Distinctive Gait Variations and Neuroimaging Correlates in Alzheimer's Disease and Cerebral Small Vessel Disease.

Both Alzheimer's disease (AD) and cerebral small vessel disease (CSVD) manifest in cognitive impairment and gait disorders. The precise similarities and differences in gait characteristics and underlying neuroimaging mechanisms remain unclear. A total of 399 participants were enrolled: 132 with...

🗓️ 2024-11-17
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreDistinctive Gait Variations and Neuroimaging Correlates in Alzheimer's Disease and Cerebral Small Vessel Disease.

New horizons in hospital-associated deconditioning: a global condition of body and mind.

Hospital-associated deconditioning is a broad term, which refers non-specifically to declines in any function of the body secondary to hospitalisation. Older people, particularly those living with frailty, are known to be at greatest risk. It has historically been most commonly...

🗓️ 2024-11-01
📰 Publication: Age And Ageing
Read MoreNew horizons in hospital-associated deconditioning: a global condition of body and mind.

Subscribe to the SCWD Newsletter

Stay Informed with the Latest Updates and Exclusive Insights!