OBJECTIVE
This study aims to analyse trajectories of disability progression in basic activities of daily living (BADLs) as a function of sarcopenia, using different cut-off points for defining low muscle strength (LMS).
METHODS
A longitudinal study included 3,328 participants from the English Longitudinal...
BACKGROUND
Sarcopenia is an age-related condition that contributes to disability and healthcare burden worldwide. Yet cross-national evidence on prevalence and multi-level risk factors is limited.
METHODS
We pooled data from 10 nationally representative or population-based ageing studies, including 144 226 adults aged ≥50 years...
PURPOSE
To compare the prognostic performance of the Asian Working Group for Sarcopenia (AWGS) 2025 diagnostic constructs-specifically height- versus body mass index (BMI)-indexed muscle mass-for discriminating functional outcomes in patients with stroke.
METHODS
From a cohort of 1246 consecutive post-acute stroke admissions, we...
BACKGROUND
Frailty and sarcopenia contribute to functional decline in older people with HIV (PWH), yet intervention data remain limited. We evaluated changes in frailty phenotype status, sarcopenia-related outcomes and functional performance during a supervised exercise trial and assessed associations between baseline...
BACKGROUND
Sarcopenia, the age-related loss of muscle mass and strength, poses a significant health and economic burden. This systematic review and meta-analysis evaluates circulating biomarkers (activin A, follistatin, growth differentiation factor (GDF-15), myostatin, growth hormone, insulin growth factor-1 (IGF-1), free and...
BACKGROUND AND AIMS
Sarcopenia is the accelerated loss of skeletal muscle mass and function associated with ageing. Sarcopenia screening consists of body composition imaging and physical function tests; however, these tests can be burdensome and inconsistent. This review aimed to synthesise...
Intrinsic Capacity (IC) is defined as the composite of physical and mental abilities an individual possesses, encompassing five domains: cognition, psychological health, sensory function, vitality, and locomotion. This construct is central to the World Health Organization's framework for assessing functional...
