Geriatrics
HQ6: Do Interventions or Assessments Using Digital Health Services Improve Sarcopenia Among Older Adults With Sarcopenia?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.
The Interplay Between Osteosarcopenia and Intrinsic Capacity: Insights and Associations With All-Cause Mortality in the Toledo Study for Healthy Aging.
BACKGROUND
Osteosarcopenia-the coexistence of osteopenia/osteoporosis and sarcopenia-is associated with numerous adverse health outcomes, but its association with intrinsic capacity (IC) remains unknown. We aimed to explore the associations of osteosarcopenia with IC and all-cause mortality in older adults.
METHODS
We conducted a cross-sectional...
Blood and urine cell-free circulating DNA in older adults with sarcopenia: a hypothesis-generating study.
PURPOSE
This preliminary study evaluated effect sizes of differences in circulating cell-free DNA (cfDNA) levels in blood and urine between older adults with and without sarcopenia.
METHODS
This was a subanalysis of the 2021 Itabashi Longitudinal Study on Aging. Twenty-four participants were selected...
HQ8: Do Nutritional Interventions Prevent the Onset and Progression of Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.
Is Appendicular Lean Soft Tissue Mass a Clinically Valid Diagnostic Marker for Sarcopenia?
AIM
Geriatric experts have long debated the inclusion of appendicular lean soft tissue mass (ALSTM) in the diagnostic criteria for sarcopenia. This study examined whether a diagnostic model for sarcopenia that excludes appendicular lean soft tissue mass (ALSTM) is equivalent to...
Implementation of blood flow restriction training in the acute geriatric unit.
BACKGROUND
Hospital-associated physical decline is common among older adults. High-load training mitigates this but, is often impractical in acute care settings. Blood flow restriction (BFR) training is a promising low-load alternative, yet clinical utility during hospitalisation is unclear.
OBJECTIVE
To evaluate feasibility, safety...
Associations between malnutrition and physical performance, sarcopenia, and frailty in older adults.
Characterizing sarcopenia and sarcopenic obesity in patients aged 65 years and over, at risk of mobility disability: a multicenter observational trial (SARA-OBS).
Aging is associated with a progressive change of body composition characterized by muscle mass decline and accumulation of adipose tissue that can lead to sarcopenia and obesity, respectively. The prevalence of sarcopenia is poorly known given the different parameters and...
Interactions between bone density and muscle mass in predicting all-cause mortality: a 10-year prospective cohort study of 1388 older men (aged 77-101 years).
Low bone density and low muscle mass are both independent risk factors for mortality in older men. However, it is unknown if these tissues interact to increase mortality risk. Elucidating this information is important as bone and muscle are modifiable...
Bioelectrical impedance analysis for sarcopenia: a systematic review and meta-analysis of diagnostic accuracy.
To evaluate the diagnostic performance of bioelectrical impedance analysis (BIA) for detecting sarcopenia across diverse populations. We conducted a search of MEDLINE, Embase, and Web of Science up to 2 January 2024. Cross-sectional, retrospective, and prospective cohort studies evaluating BIA's...
Prioritizing integrated care and sarcopenia prevention for healthy ageing across Asia.
Osteosarcopenia and frailty risk in community-dwelling older adults: A follow-up of the I-Lan Longitudinal Aging Study.
Osteosarcopenia is suggested to be on the causal pathway to frailty; however, data on this topic is scarce, and it is unclear if osteosarcopenia is associated with frailty risk. To investigate if osteosarcopenia is associated with frailty risk in community-dwelling...
Prevalence of sarcopenia in middle-aged and older adults with cognitive impairment: a meta-analysis.
Cognitive impairment, dementia and sarcopenia significantly reduce the quality of life in middle-aged and older adults by impairing daily functioning, making cognitive decline a major concern for healthcare professionals. To estimate the prevalence of sarcopenia and probable sarcopenia in middle-aged...
Sarcopenia in heart failure: Comparison of prognostic value between the Asian working Group for Sarcopenia 2014 and 2019 criteria.
Sarcopenia is a prevalent comorbidity among older patients with heart failure. This study aimed to evaluate the differences between sarcopenia diagnosed using the Asian Working Group for Sarcopenia (AWGS) 2014 and 2019 criteria in older patients with heart failure. This...
Plasma brain-derived neurotrophic factor concentrations are elevated in community-dwelling adults with sarcopenia.
The scalability of a blood-based sarcopenia assessment has generated interest in circulating markers that may enhance management strategies. Data regarding the relevance of brain derived neurotrophic factor (BDNF), a regulator of neuroplasticity, to sarcopenia in community-dwelling adults are scarce. We...
