Sarcopenia and Frailty in Type 2 Diabetes Mellitus: An Overlooked Challenge.
🗓️ 2026-07-14
📰 Publication: Diabetes & Metabolism Journal
Read MoreSarcopenia and Frailty in Type 2 Diabetes Mellitus: An Overlooked Challenge.Diabetes_mellitus
Sarcopenic Obesity and Risk of Incident Type 2 Diabetes: A Prospective Cohort Study and Landmark Analysis From the UK Biobank.
OBJECTIVE
To examine whether sarcopenic obesity (SO) is associated with incident type 2 diabetes (T2D) beyond obesity or sarcopenia alone and whether associations differ by sex, age, and transitions in body composition phenotypes over time.
RESEARCH DESIGN AND METHODS
We studied 479,607 diabetes-free...
🗓️ 2026-07-13
📰 Publication: Diabetes Care
Read MoreSarcopenic Obesity and Risk of Incident Type 2 Diabetes: A Prospective Cohort Study and Landmark Analysis From the UK Biobank.Sarcopenia in Diabetes: A proposal on integrating muscle assessment and nutritional intervention in people living with diabetes.
Sarcopenia is a progressive muscle disease characterized by loss of skeletal muscle mass and strength, commonly associated with ageing and chronic diseases. Type 2 diabetes mellitus (T2DM) accelerates its development through insulin resistance, chronic inflammation, oxidative stress, and hyperglycaemia. Sarcopenia...
🗓️ 2026-05-27
📰 Publication: Diabetes Research And Clinical Practice
Read MoreSarcopenia in Diabetes: A proposal on integrating muscle assessment and nutritional intervention in people living with diabetes.Body Composition Changes in Patients on GLP-1 Receptor Agonists Undergoing an Intensive Cardiac Rehabilitation Program.
BACKGROUND
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are widely used for type 2 diabetes and obesity and produce significant weight loss. However, concerns have emerged about potential loss of skeletal muscle mass (SMM) with pharmacologic weight reduction, particularly in older adults...
🗓️ 2026-05-21
📰 Publication: European Journal Of Preventive Cardiology
Read MoreBody Composition Changes in Patients on GLP-1 Receptor Agonists Undergoing an Intensive Cardiac Rehabilitation Program.Prevalence and Prognostic Impact of the Coexistence of Cachexia and Sarcopenia in Patients With Chronic Liver Diseases.
BACKGROUND
Cachexia and sarcopenia are prevalent, inflammation-linked syndromes in chronic liver disease that worsen outcomes. To our knowledge, their coexistence in a single chronic liver disease cohort has not been systematically examined. In this study, we evaluated the prevalence, clinical features...
🗓️ 2026-05-06
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MorePrevalence and Prognostic Impact of the Coexistence of Cachexia and Sarcopenia in Patients With Chronic Liver Diseases.Associations of Body Composition and Physical Function With Incident Diabetes in Older Adults: A 14-Year Prospective Cohort Study.
BACKGROUND
Longitudinal associations between age-related changes in body composition, physical performance and incident diabetes mellitus (DM) in older adults and the mediating role of branched-chain amino acids (BCAAs) remain understudied.
METHODS
This prospective cohort study included 4000 community-dwelling older adults at baseline. Longitudinal...
🗓️ 2026-04-20
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreAssociations of Body Composition and Physical Function With Incident Diabetes in Older Adults: A 14-Year Prospective Cohort Study.Muscle Atrophy-Related Adverse Events of Antidiabetic Drug Classes: A Pharmacovigilance Analysis Using VigiBase Data.
BACKGROUND
Diabetes mellitus-a chronic metabolic disorder associated with an increased risk of muscle atrophy-can significantly impact patients' quality of life and overall health outcomes. While antidiabetic medications are crucial for managing blood glucose levels, some have been linked to muscle-related adverse...
🗓️ 2026-04-15
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreMuscle Atrophy-Related Adverse Events of Antidiabetic Drug Classes: A Pharmacovigilance Analysis Using VigiBase Data.Muscle Movement and Metabolism: Exercise and Skeletal Muscle as Mediators of Health. A Report from the 26th Annual Harvard Nutrition Obesity Symposium, 2025.
Skeletal muscle is a crucial facilitator of many of the effects of exercise on metabolic health. Intrinsic myocellular mechanisms, exercise-induced myokine secretion, and crosstalk between multiple organ systems contribute to the maintenance of energy homeostasis, cardiovascular health, strength, cognition, and...
🗓️ 2026-03-12
📰 Publication: American Journal Of Clinical Nutrition
Read MoreMuscle Movement and Metabolism: Exercise and Skeletal Muscle as Mediators of Health. A Report from the 26th Annual Harvard Nutrition Obesity Symposium, 2025.Glucagon-like peptide-1 receptor agonists and muscle strength changes in older adults: Risks beyond muscle mass reductions.
Gastric inhibitory polypeptide (GIP)/Glucagon-like peptide-1 (GLP-1) receptor agonists are increasingly prescribed for the management of obesity and type 2 diabetes, yet research pertinent to their effects on muscle health is limited. Considering the central role of muscle strength as a...
🗓️ 2026-01-24
📰 Publication: British Journal Of Pharmacology
Read MoreGlucagon-like peptide-1 receptor agonists and muscle strength changes in older adults: Risks beyond muscle mass reductions.Can a consumer-grade bioimpedance device accurately estimate sarcopenia in women with type 2 diabetes? A cross-sectional agreement study with dual-energy X-ray absorptiometry.
AIMS
To evaluate the diagnostic performance of a consumer-grade bioelectrical impedance analyzer (OMRON HBF-514C) against dual-energy X-ray absorptiometry (DXA) for detecting sarcopenia in women with type 2 diabetes (T2DM).
METHODS
In this cross‑sectional study, 103 women with T2DM underwent body composition assessment using...
🗓️ 2025-12-24
📰 Publication: Diabetes Research And Clinical Practice
Read MoreCan a consumer-grade bioimpedance device accurately estimate sarcopenia in women with type 2 diabetes? A cross-sectional agreement study with dual-energy X-ray absorptiometry.Consensus statement on vitamin D role in metabolic health.
The 8th International Conference Controversies in Vitamin D, held in September 2024, convened leading experts to address the multifaceted role of vitamin D in human health. Key discussions focused on its influence on metabolic health, including effects on sarcopenia, muscle...
🗓️ 2025-12-24
📰 Publication: Metabolism-Clinical And Experimental
Read MoreConsensus statement on vitamin D role in metabolic health.Underweight and Mortality in Type 2 Diabetes: A Nationwide Retrospective Cohort Study.
BACKGROUND
Being underweight is an underrecognized risk factor for mortality among individuals with type 2 diabetes (T2D). This study aimed to evaluate the associations of underweight status with mortality among individuals with T2D.
METHODS
This nationwide, retrospective, population-based cohort study used data from...
🗓️ 2025-12-06
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreUnderweight and Mortality in Type 2 Diabetes: A Nationwide Retrospective Cohort Study.Tailored Exercise Prescription for People with COPD and Clinically Relevant Comorbidities: A Consensus Statement of the EXPERT Working Group and Experts in Pulmonary Rehabilitation.
Chronic obstructive pulmonary disease (COPD) is a heterogeneous chronic lung condition often accompanied by comorbidities and systemic manifestations that affect the person's clinical condition and prognosis and often require specific treatment. Therefore, the management of COPD extends beyond treatment for...
🗓️ 2025-12-04
📰 Publication: Sports Medicine
Read MoreTailored Exercise Prescription for People with COPD and Clinically Relevant Comorbidities: A Consensus Statement of the EXPERT Working Group and Experts in Pulmonary Rehabilitation.Targeting Progesterone Receptor Membrane Component 1 to Improve Muscle Development and Glucose Homeostasis.
BACKGROUND
Type 2 diabetes mellitus (T2D) arises from the interplay between peripheral insulin resistance and pancreatic β-cell dysfunction, ultimately leading to impaired glucose utilization and chronic hyperglycemia. Despite therapeutic advances, the multifactorial nature of T2D continues to demand the development of...
🗓️ 2025-11-10
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreTargeting Progesterone Receptor Membrane Component 1 to Improve Muscle Development and Glucose Homeostasis.Glucagon-like peptide-1 receptor agonists and sarcopenia-related markers in diabetes: A systematic review and meta-analysis.
AIMS
GLP-1 receptor agonists (GLP-1RAs) are first-line therapies for type 2 diabetes (T2DM) due to their additional weight-lowering and cardiovascular benefits. However, their impact on muscle mass is debated, posing a concern for sarcopenia in older adults with T2DM. This systematic...
🗓️ 2025-11-05
📰 Publication: Clinical Nutrition
Read MoreGlucagon-like peptide-1 receptor agonists and sarcopenia-related markers in diabetes: A systematic review and meta-analysis.Muscle oxygen saturation stratification by photoacoustic imaging in diabetic sarcopenia: Association with disease status.
Sarcopenia, commonly observed in diabetes, is characterized by reduced muscle mass and function. However, the relationship between muscle oxygen saturation (SO₂) and sarcopenia remains unclear. Photoacoustic imaging (PAI) offers a promising method for assessment. This study aimed to evaluate SO₂...
🗓️ 2025-12-01
📰 Publication: Photoacoustics
Read MoreMuscle oxygen saturation stratification by photoacoustic imaging in diabetic sarcopenia: Association with disease status.