Heart_failure

Air pollution exacerbates cardiovascular-kidney-metabolic syndrome and sarcopenia comorbidity via shared genetic-epigenetic mechanisms: A multi-omics and Mendelian Randomization study.

<p><b>BACKGROUND</b></p><p>Ambient air pollution aggravates cardiovascular-kidney-metabolic (CKM) disorders and sarcopenia, yet the shared genetic and epigenetic mechanisms that underlie their frequent co-occurrence remain poorly understood.</p><p><b>METHODS</b></p><p>We integrated genome-wide association study (GWAS) data for CKM components (cardiovascular disease [CVD], chronic kidney disease [CKD],...

๐Ÿ—“๏ธ 2025-11-22
๐Ÿ“ฐ Publication: Metabolism-Clinical And Experimental
Read MoreAir pollution exacerbates cardiovascular-kidney-metabolic syndrome and sarcopenia comorbidity via shared genetic-epigenetic mechanisms: A multi-omics and Mendelian Randomization study.

Differences in peak oxygen uptake in heart failure patients with and without cachexia: A systematic review and meta-analysis.

Chronic heart failure (CHF) is characterized by reduced peak oxygen consumption (VO 2peak). Cachexia may exacerbate the decline in VO 2peak from reductions in muscle mass and strength. We sought to assess differences in VO 2peak between patients with CHF...

๐Ÿ—“๏ธ 2025-11-17
Read MoreDifferences in peak oxygen uptake in heart failure patients with and without cachexia: A systematic review and meta-analysis.

Different Pattern in Circulating MicroRNA-22-3p Levels Between Patients With Primary Versus Secondary Sarcopenia.

Sarcopenia, characterized by decreased skeletal muscle mass and strength, is classified as "primary" (due to aging) or "secondary" (due to diseases). MicroRNA-22-3p (miR-22) regulates muscle differentiation and function. We assessed the diagnostic value of circulating miR-22 levels in patients with...

๐Ÿ—“๏ธ 2025-11-15
๐Ÿ“ฐ Publication: Aging Cell
Read MoreDifferent Pattern in Circulating MicroRNA-22-3p Levels Between Patients With Primary Versus Secondary Sarcopenia.

Prognostic role of sarcopenia in heart failure patients.

<p><b>AIM</b></p><p>Sarcopenia is common in heart failure (HF) patients; however, there are no data regarding the possible long-term prognostic role of sarcopenia in younger adults with chronic HF without malnutrition. The aim of this study was to examine the long-term prognostic...

๐Ÿ—“๏ธ 2025-10-29
๐Ÿ“ฐ Publication: Cardiovascular Diabetology
Read MorePrognostic role of sarcopenia in heart failure patients.

Body composition in patients with obesity-related heart failure with preserved ejection fraction: A comparison study.

Appendicular lean mass index is a major determinant of cardiorespiratory fitness in patients with obesity-related heart failure with preserved ejection fraction (HFpEF). Moreover, appendicular lean mass index can be used to diagnose sarcopenia and sarcopenic obesity in this population. We...

๐Ÿ—“๏ธ 2025-09-20
๐Ÿ“ฐ Publication: Journal Of Parenteral And Enteral Nutrition
Read MoreBody composition in patients with obesity-related heart failure with preserved ejection fraction: A comparison study.

Sarcopenia Assessment Using Fully Automated Deep Learning Predicts Cardiac Allograft Survival in Heart Transplant Recipients.

Sarcopenia is associated with adverse outcomes in patients with end-stage heart failure. Muscle mass can be quantified via manual segmentation of computed tomography images, but this approach is time-consuming and subject to interobserver variability. We sought to determine whether fully...

๐Ÿ—“๏ธ 2025-08-20
Read MoreSarcopenia Assessment Using Fully Automated Deep Learning Predicts Cardiac Allograft Survival in Heart Transplant Recipients.

Patient Focus: Understanding Muscle Wasting in Heart Failure. An explanation of "Consolidating Concepts from Recent International Expert Consensus on Sarcopenia: Implications for Heart Failure Management".

๐Ÿ—“๏ธ 2025-07-04
๐Ÿ“ฐ Publication: Journal Of Cardiac Failure
Read MorePatient Focus: Understanding Muscle Wasting in Heart Failure. An explanation of "Consolidating Concepts from Recent International Expert Consensus on Sarcopenia: Implications for Heart Failure Management".

Consolidating Concepts from Recent International Expert Consensus on Sarcopenia: Implications for Heart Failure Management.

Heart failure is a clinical syndrome associated with a range of pathophysiological disorders including secondary sarcopenia that reduces patients' quality of life, mobility, physical fitness and capacity to undergo rehabilitation and recovery from acute decompensation. Although international expert writing groups...

๐Ÿ—“๏ธ 2025-06-16
๐Ÿ“ฐ Publication: Journal Of Cardiac Failure
Read MoreConsolidating Concepts from Recent International Expert Consensus on Sarcopenia: Implications for Heart Failure Management.

Sarcopenia in heart failure: Comparison of prognostic value between the Asian working Group for Sarcopenia 2014 and 2019 criteria.

Sarcopenia is a prevalent comorbidity among older patients with heart failure. This study aimed to evaluate the differences between sarcopenia diagnosed using the Asian Working Group for Sarcopenia (AWGS) 2014 and 2019 criteria in older patients with heart failure. This...

๐Ÿ—“๏ธ 2025-05-06
๐Ÿ“ฐ Publication: Geriatrics & Gerontology International
Read MoreSarcopenia in heart failure: Comparison of prognostic value between the Asian working Group for Sarcopenia 2014 and 2019 criteria.

Prevalence, Characteristics, and Prognostic Associations of Cachexia Diagnosed Using Asian Working Group for Cachexia 2023 Criteria in Older Adults With Heart Failure.

Few studies have examined the characteristics of heart failure (HF) patients with cachexia using the Asian Working Group for Cachexia (AWGC) 2023 criteria. This study assessed the characteristics and clinical impact of cachexia in older adults with HF. Results of...

๐Ÿ—“๏ธ 2025-04-18
๐Ÿ“ฐ Publication: Circulation Journal
Read MorePrevalence, Characteristics, and Prognostic Associations of Cachexia Diagnosed Using Asian Working Group for Cachexia 2023 Criteria in Older Adults With Heart Failure.

Association of body composition with left ventricular remodeling and outcomes in diabetic heart failure with reduced ejection fraction: assessment of sarcopenic obesity using cardiac MRI.

Obesity is common in the heart failure (HF) population and is regarded as an important risk factor for developing HF. Greater skeletal muscle mass has shown to be the underlying protective factor against cardiac failure. Since diabetic mellitus (DM) can...

๐Ÿ—“๏ธ 2025-02-17
๐Ÿ“ฐ Publication: Cardiovascular Diabetology
Read MoreAssociation of body composition with left ventricular remodeling and outcomes in diabetic heart failure with reduced ejection fraction: assessment of sarcopenic obesity using cardiac MRI.

Growth Differentiation Factor-15 Isย Associated With Congestion-Related Anorexia and Weight Loss in Advancedย Heartย Failure.

Growth differentiation factor (GDF)-15 is a pleiotropic cytokine that is associated with appetite-suppressing effects and weight loss in patients with malignancy. This study aims to investigate the relationships between GDF-15 levels, anorexia, cachexia, and clinical outcomes in patients with advanced...

๐Ÿ—“๏ธ 2025-01-08
๐Ÿ“ฐ Publication: Jacc-Heart Failure
Read MoreGrowth Differentiation Factor-15 Isย Associated With Congestion-Related Anorexia and Weight Loss in Advancedย Heartย Failure.

A fluorescent aptasensor for deoxynivalenol detection based on Nb.BbvCI-assisted targeted-responsive three-way junctions integrated DNA walking machine.

Deoxynivalenol (DON) contamination in cereals is a widespread issue with global implications, necessitating the development of efficient detection methods. Here, a fluorescent aptasensor integrating target-responsive DNA three-way junction (TWJ) and DNA walking machine was developed to detect DON. The DON-specific...

๐Ÿ—“๏ธ 2024-12-06
๐Ÿ“ฐ Publication: Food Chemistry
Read MoreA fluorescent aptasensor for deoxynivalenol detection based on Nb.BbvCI-assisted targeted-responsive three-way junctions integrated DNA walking machine.

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