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Obesity

Sarcopenic obesity defined by Japanese Working Group on Sarcopenic Obesity in post-stroke inpatients: prevalence and clinical implications.

Sarcopenic obesity (SO) is characterized by the coexistence of sarcopenia and obesity, associated with adverse health outcomes. This study aimed to investigate the prevalence of SO as defined by the recently published Japanese Working Group on Sarcopenic Obesity (JWGSO) criteria...
๐Ÿ—“๏ธ 2025-04-16
Read MoreSarcopenic obesity defined by Japanese Working Group on Sarcopenic Obesity in post-stroke inpatients: prevalence and clinical implications.

Prepregnancy Obesity Reprograms Offspring Skeletal Muscle Fibre Transition Through H3K9me3.

Maternal prepregnancy obesity predisposes offspring to obesity and metabolic disorders, yet its impact on skeletal muscle fibre transition remains unclear. Given that skeletal muscle plays a crucial role in systemic metabolism, we investigated how maternal prepregnancy high-fat diet (HFD) influences...
๐Ÿ—“๏ธ 2025-04-01
๐Ÿ“ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MorePrepregnancy Obesity Reprograms Offspring Skeletal Muscle Fibre Transition Through H3K9me3.

Associations between sarcopenic, obesity, and sarcopenic obesity and metabolic syndrome in adults aged 45ย Years or older: A prospective cohort study from the China health and retirement longitudinal study.

Although previous studies have reported associations between sarcopenic obesity (SO) and metabolic syndrome (MetS), the findings remain inconsistent. This study aimed to investigate the associations between sarcopenia, obesity, and MetS, and to determine whether sarcopenic obesity synergistically increases the risk...
๐Ÿ—“๏ธ 2025-04-05
๐Ÿ“ฐ Publication: Clinical Nutrition
Read MoreAssociations between sarcopenic, obesity, and sarcopenic obesity and metabolic syndrome in adults aged 45ย Years or older: A prospective cohort study from the China health and retirement longitudinal study.

Distinct gut microbiota signatures in older people with sarcopenic obesity and sarcopenia without obesity.

Previous evidence suggests that gut dysbiosis plays an important role in the development and progression of sarcopenia and sarcopenic obesity (SO), but evidence supporting this association is lacking. Thus, this study aimed to investigate the characteristics of gut microbiota in...
๐Ÿ—“๏ธ 2025-04-08
๐Ÿ“ฐ Publication: Clinical Nutrition
Read MoreDistinct gut microbiota signatures in older people with sarcopenic obesity and sarcopenia without obesity.

Weight cycling and its effects on muscle mass, sarcopenia and sarcopenic obesity.

The prevalence of obesity is rising around the world, as the number of subjects dieting and experiencing weight loss followed by unintentional weight regain, the so-called weight cycling (WC). In this narrative review we sought to reveal the effects of...
๐Ÿ—“๏ธ 2025-04-15
๐Ÿ“ฐ Publication: Reviews In Endocrine & Metabolic Disorders
Read MoreWeight cycling and its effects on muscle mass, sarcopenia and sarcopenic obesity.

Physical training reduces cell senescence and associated insulin resistance in skeletal muscle.

Cellular senescence (CS) is a key aging process that leads to irreversible cell cycle arrest and an altered secretory phenotype. In skeletal muscle (SkM), the accumulation of senescent cells contributes to sarcopenia. Despite exercise being a known intervention for maintaining...
๐Ÿ—“๏ธ 2025-03-22
๐Ÿ“ฐ Publication: Molecular Metabolism
Read MorePhysical training reduces cell senescence and associated insulin resistance in skeletal muscle.

Sarcopenic obesity and the risk of atrial fibrillation in non-diabetic older adults: A prospective cohort study.

Evidence of an association between sarcopenic obesity (SO) and the risk of long-term atrial fibrillation (AF) is lacking, and the underlying involvement of insulin resistance (IR) and inflammation is not clear. This community-based prospective cohort study evaluated sarcopenia, obesity, and...
๐Ÿ—“๏ธ 2025-03-04
๐Ÿ“ฐ Publication: Clinical Nutrition
Read MoreSarcopenic obesity and the risk of atrial fibrillation in non-diabetic older adults: A prospective cohort study.

The association between sarcopenic obesity and malnutrition in community-dwelling older adults.

The increase in fat tissue and the decrease in muscle mass with advancing age have prompted researchers to explore the coexistence of sarcopenia and obesity, i.e. sarcopenic obesity (SO). SO may lead to malnutrition due to poor diet quality, while...
๐Ÿ—“๏ธ 2025-02-02
๐Ÿ“ฐ Publication: Age And Ageing
Read MoreThe association between sarcopenic obesity and malnutrition in community-dwelling older adults.

Body Composition and Intradialytic Exercise in Kidney Disease: A Combined Analysis of the PEDAL and CYCLE-HD Randomised Controlled Trials.

Haemodialysis patients are at high risk of myopenic obesity, necessitating effective nutritional status monitoring and intervention strategies. This combined analysis of two clinical trials (PEDAL trial and CYCLE-HD study) aimed to (i) determine the clinical utility of body mass index...
๐Ÿ—“๏ธ 2025-04-01
๐Ÿ“ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreBody Composition and Intradialytic Exercise in Kidney Disease: A Combined Analysis of the PEDAL and CYCLE-HD Randomised Controlled Trials.

Association of body composition with left ventricular remodeling and outcomes in diabetic heart failure with reduced ejection fraction: assessment of sarcopenic obesity using cardiac MRI.

Obesity is common in the heart failure (HF) population and is regarded as an important risk factor for developing HF. Greater skeletal muscle mass has shown to be the underlying protective factor against cardiac failure. Since diabetic mellitus (DM) can...
๐Ÿ—“๏ธ 2025-02-17
๐Ÿ“ฐ Publication: Cardiovascular Diabetology
Read MoreAssociation of body composition with left ventricular remodeling and outcomes in diabetic heart failure with reduced ejection fraction: assessment of sarcopenic obesity using cardiac MRI.

Erector Spinae Muscle to Epicardial Visceral Fat Ratio on Chest CT Predicts the Severity of Coronavirus Disease 2019.

Chest computed tomography (CT) is a valuable tool for diagnosing and predicting the severity of coronavirus disease 2019 (COVID-19) and assessing extrapulmonary organs. Reduced muscle mass and visceral fat accumulation are important features of a body composition phenotype in which...
๐Ÿ—“๏ธ 2025-02-01
๐Ÿ“ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreErector Spinae Muscle to Epicardial Visceral Fat Ratio on Chest CT Predicts the Severity of Coronavirus Disease 2019.

Sheer drop ahead: reviewing sarcopenia outcomes in elderly patients undergoing bariatric surgery.

The global prevalence of obesity among elderly patients continues to rise. Despite the availability of new antiobesity medications, bariatric surgery remains an effective treatment option for carefully selected candidates. However, it is not risk-free, especially in a vulnerable population, predisposing...
๐Ÿ—“๏ธ 2025-02-08
๐Ÿ“ฐ Publication: Reviews In Endocrine & Metabolic Disorders
Read MoreSheer drop ahead: reviewing sarcopenia outcomes in elderly patients undergoing bariatric surgery.

Nicotinamide Phosphoribosyltransferase Acetylation Mediating Muscle Dysfunction Contributes to Sleep Apnoea in Obesity.

Obstructive sleep apnoea (OSA) occurs frequently among individuals with obesity, which is attributed to upper airway muscle dysfunction. Muscle function is regulated by the dynamic balance of the nicotinamide adenine dinucleotide (NAD+) and its reduced form (NADH), which is controlled...
๐Ÿ—“๏ธ 2025-02-01
๐Ÿ“ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreNicotinamide Phosphoribosyltransferase Acetylation Mediating Muscle Dysfunction Contributes to Sleep Apnoea in Obesity.

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