Obesity

Association between sarcopenic obesity and worsening physical performance in patients undergoing hemodialysis: The REPnet-HD study.

OBJECTIVE

Sarcopenic obesity, defined by excess fat mass with concurrent sarcopenia, is an emerging public health concern. In patients undergoing hemodialysis, reduced physical performance is associated with poor prognosis. This study aimed to investigate association between sarcopenic obesity and worsening physical...

🗓️ 2026-03-21
📰 Publication: Journal Of Renal Nutrition
Read MoreAssociation between sarcopenic obesity and worsening physical performance in patients undergoing hemodialysis: The REPnet-HD study.

Muscle Movement and Metabolism: Exercise and Skeletal Muscle as Mediators of Health. A Report from the 26th Annual Harvard Nutrition Obesity Symposium, 2025.

Skeletal muscle is a crucial facilitator of many of the effects of exercise on metabolic health. Intrinsic myocellular mechanisms, exercise-induced myokine secretion, and crosstalk between multiple organ systems contribute to the maintenance of energy homeostasis, cardiovascular health, strength, cognition, and...

🗓️ 2026-03-12
📰 Publication: American Journal Of Clinical Nutrition
Read MoreMuscle Movement and Metabolism: Exercise and Skeletal Muscle as Mediators of Health. A Report from the 26th Annual Harvard Nutrition Obesity Symposium, 2025.

High Fat Diet and Obesity Each Increase Tumor Cell Proliferation and Muscle Wasting in Experimental Cancer Cachexia.

High fat diet (HFD) and associated obesity are suggested to predispose to cancer development, complicate cancer treatment, and accelerate mortality. Paradoxically, obese patients with lung cancer are reported to live longer, suggesting that high body mass is protective. Given that...

🗓️ 2026-02-21
📰 Publication: American Journal Of Physiology-Cell Physiology
Read MoreHigh Fat Diet and Obesity Each Increase Tumor Cell Proliferation and Muscle Wasting in Experimental Cancer Cachexia.

iCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025.

There are a number of guidelines on how to manage obesity, but inconsistencies in healthcare access, varying infrastructure, resource constraints and diverse local practices restrict their global applicability. This underscores the need for universal recommendations that address the unique challenges...

🗓️ 2026-02-13
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreiCARDIO Alliance Global Implementation Guidelines for the Management of Obesity 2025.

Glucagon-like peptide-1 receptor agonists and muscle strength changes in older adults: Risks beyond muscle mass reductions.

Gastric inhibitory polypeptide (GIP)/Glucagon-like peptide-1 (GLP-1) receptor agonists are increasingly prescribed for the management of obesity and type 2 diabetes, yet research pertinent to their effects on muscle health is limited. Considering the central role of muscle strength as a...

🗓️ 2026-01-24
📰 Publication: British Journal Of Pharmacology
Read MoreGlucagon-like peptide-1 receptor agonists and muscle strength changes in older adults: Risks beyond muscle mass reductions.

Identification of Sarcopenic Obesity by Fat-to-Muscle Ratio in Older Adults: A Cohort Study.

BACKGROUND

The diagnosis of sarcopenic obesity has been established in Europe and Japan, but screening tools remain inconsistent and lack standardization. The fat-to-muscle ratio (FMR) is a potential screening measure for sarcopenic obesity; however, its diagnostic accuracy compared with other tools...

🗓️ 2026-01-21
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreIdentification of Sarcopenic Obesity by Fat-to-Muscle Ratio in Older Adults: A Cohort Study.

Impact of probiotic, prebiotic, and synbiotic supplementation on the gut microbiome in older adults with sarcopenia, obesity, and sarcopenic obesity.

Gut microbiome plays an important role in several metabolic, immune, and inflammatory pathways; however, there is limited evidence for its role in body composition and musculoskeletal health. Sarcopenia, defined as a loss of skeletal muscle mass and function, and obesity,...

🗓️ 2026-01-09
📰 Publication: Osteoporosis International
Read MoreImpact of probiotic, prebiotic, and synbiotic supplementation on the gut microbiome in older adults with sarcopenia, obesity, and sarcopenic obesity.

Plant-based protein for older adults with obesity.

The global syndemic of obesity, undernutrition, and climate change - three interconnected challenges - threatens both human and planetary health. This review focuses on one critical intersection: older populations living with overweight and obesity in the context of sustainable nutrition....

🗓️ 2025-12-26
📰 Publication: Proceedings Of The Nutrition Society
Read MorePlant-based protein for older adults with obesity.

Underweight and Mortality in Type 2 Diabetes: A Nationwide Retrospective Cohort Study.

BACKGROUND

Being underweight is an underrecognized risk factor for mortality among individuals with type 2 diabetes (T2D). This study aimed to evaluate the associations of underweight status with mortality among individuals with T2D.

METHODS

This nationwide, retrospective, population-based cohort study used data from...

🗓️ 2025-12-06
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreUnderweight and Mortality in Type 2 Diabetes: A Nationwide Retrospective Cohort Study.

Accelerometer-Determined Physical Activity and Sarcopenic Obesity Risk in Older European Men and Women.

BACKGROUND

Sarcopenic obesity (SO) is characterized by the presence of both obesity and sarcopenia and is related to disability and loss of independence in older adults. The extent to which time spent in light physical activity (LPA), or moderate-to-vigorous physical activity...

🗓️ 2025-12-05
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreAccelerometer-Determined Physical Activity and Sarcopenic Obesity Risk in Older European Men and Women.

Sarcopenic Obesity Phenotype Index (SOPi): A Population-Based Study.

BACKGROUND

Sarcopenic obesity (SO) is a clinical condition defined by the coexistence of high body fat mass and low muscle function and mass, which increases the risk of adverse health outcomes, including disability and mortality. Early detection and frequent monitoring of...

🗓️ 2025-10-01
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreSarcopenic Obesity Phenotype Index (SOPi): A Population-Based Study.

Impact of Annual Dry Weight Changes on Mortality and Cardiovascular Outcomes in Patients Undergoing Haemodialysis.

BACKGROUND

While obesity confers a survival advantage, weight loss adversely affects the survival of patients undergoing haemodialysis. However, given the limited information regarding its long-term effects on mortality and cardiovascular events, the health benefits of weight gain remain uncertain, particularly in...

🗓️ 2025-10-01
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreImpact of Annual Dry Weight Changes on Mortality and Cardiovascular Outcomes in Patients Undergoing Haemodialysis.

Body composition in patients with obesity-related heart failure with preserved ejection fraction: A comparison study.

Appendicular lean mass index is a major determinant of cardiorespiratory fitness in patients with obesity-related heart failure with preserved ejection fraction (HFpEF). Moreover, appendicular lean mass index can be used to diagnose sarcopenia and sarcopenic obesity in this population. We...

🗓️ 2025-09-20
📰 Publication: Journal Of Parenteral And Enteral Nutrition
Read MoreBody composition in patients with obesity-related heart failure with preserved ejection fraction: A comparison study.

Adipose-Derived Extracellular Vesicles and Intercellular Crosstalk With Skeletal Muscle: Implications for Sarcopenic Obesity and Metabolic Dysregulation.

Sarcopenic obesity, characterized by the concurrent presence of excess adiposity and diminished skeletal muscle mass and function, is closely linked to frailty, chronic inflammation, and insulin resistance. The increasing prevalence of sarcopenic obesity is driven by the global aging population,...

🗓️ 2025-08-13
📰 Publication: Obesity Reviews
Read MoreAdipose-Derived Extracellular Vesicles and Intercellular Crosstalk With Skeletal Muscle: Implications for Sarcopenic Obesity and Metabolic Dysregulation.

Characterizing sarcopenia and sarcopenic obesity in patients aged 65 years and over, at risk of mobility disability: a multicenter observational trial (SARA-OBS).

Aging is associated with a progressive change of body composition characterized by muscle mass decline and accumulation of adipose tissue that can lead to sarcopenia and obesity, respectively. The prevalence of sarcopenia is poorly known given the different parameters and...

🗓️ 2025-08-04
Read MoreCharacterizing sarcopenia and sarcopenic obesity in patients aged 65 years and over, at risk of mobility disability: a multicenter observational trial (SARA-OBS).

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