EXERCISE

Muscle failure and risk of adverse outcomes in older adults: a derivation and multicohort validation study.

BACKGROUND

Sarcopenia is inconsistently defined, and its definition might not adequately capture muscle failure, underlying disability, and other adverse outcomes in older adults. We aimed to develop and validate an evidence-based, outcome-driven model of muscle failure.

METHODS

In this derivation and multicohort validation...

🗓️ 2026-05-13
Read MoreMuscle failure and risk of adverse outcomes in older adults: a derivation and multicohort validation study.

Beyond the Lungs: The Role of Extrapulmonary Manifestations in the Quality of Life of Indians with Chronic Airway Diseases.

PURPOSE

Chronic airway diseases (CAD) including Chronic obstructive pulmonary diseases (COPD), persistent asthma (≥2weekly episodes) and bronchiectasis, exhibit overlapping extrapulmonary manifestations potentially affecting health-related quality-of-life (HRQOL). The study objective was to quantify HRQOL of CAD patients and identify impact of associated...

🗓️ 2026-05-09
📰 Publication: Respiratory Medicine
Read MoreBeyond the Lungs: The Role of Extrapulmonary Manifestations in the Quality of Life of Indians with Chronic Airway Diseases.

Exercise Modalities to Preserve Muscle Mass and Bone Health After Metabolic Bariatric Surgery.

BACKGROUND

Metabolic bariatric surgery (MBS) effectively reduces fat mass (FM), but how to best preserve muscle and bone mass after MBS is unknown.

OBJECTIVE

This study aimed to evaluate the effect of aerobic, resistance and combined exercise regimens on body composition, bone mineral...

🗓️ 2026-04-30
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreExercise Modalities to Preserve Muscle Mass and Bone Health After Metabolic Bariatric Surgery.

A comprehensive review of cancer-induced cardiac wasting.

Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural...

🗓️ 2026-04-23
📰 Publication: British Journal Of Pharmacology
Read MoreA comprehensive review of cancer-induced cardiac wasting.

Disuse-Induced Muscle Atrophy and Muscle Weakness From Hospitalization to Spaceflight: Exercise Succeeds in Prevention and Treatment-A Meta-Analysis.

BACKGROUND

Exercise has been proposed as both a preventive and therapeutic countermeasure; however, its effectiveness across different disuse conditions and timings of implementation remains uncertain.

METHODS

This systematic review and meta-analysis (PROSPERO: CRD42021256599) searched ClinicalTrials.gov, Cochrane Central, PubMed, SPORTDiscus, Web of Science, Scopus,...

🗓️ 2026-04-15
📰 Publication: Journal Of Cachexia Sarcopenia And Muscle
Read MoreDisuse-Induced Muscle Atrophy and Muscle Weakness From Hospitalization to Spaceflight: Exercise Succeeds in Prevention and Treatment-A Meta-Analysis.

HQ7: Does Exercise Prevent the Onset and Progression of Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ7: Does Exercise Prevent the Onset and Progression of Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

HQ9: Do Exercise Interventions Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-04-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ9: Do Exercise Interventions Prevent the Onset and Progression of Sarcopenia in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

The sarcopenia-pain connection: why mechanisms matter for patient care?

Sarcopenia and pain are two highly prevalent conditions in aging populations, each exerting profound effects on mobility, independence, and quality of life. Emerging evidence demonstrates that these conditions are not merely coincidental but are closely interconnected through shared biological, mechanical,...

🗓️ 2026-04-15
Read MoreThe sarcopenia-pain connection: why mechanisms matter for patient care?

Feasibility of social media health education plus exercise in older adults with possible sarcopenia.

Possible sarcopenia is prevalent among community-dwelling young-old adults, yet scalable, evidence-based social media interventions for prevention remain limited. This study evaluated the feasibility and acceptability of a Social media-based Health Education plus Exercise Programme (SHEEP) delivered via TikTok, along with...

🗓️ 2026-04-09
Read MoreFeasibility of social media health education plus exercise in older adults with possible sarcopenia.

Moderate Aerobic Training Causes Muscle Wasting in a DMBA-Induced Sarcoma Rat Model.

Cancer cachexia, characterized by severe body weight loss, negatively affects patient quality of life and survival. Although moderate exercise benefits healthy and chronically ill individuals, and the effect of exercise in cachexia generally appears beneficial, conflicting results have been reported...

🗓️ 2026-03-14
📰 Publication: International Journal Of Molecular Sciences
Read MoreModerate Aerobic Training Causes Muscle Wasting in a DMBA-Induced Sarcoma Rat Model.

Muscle Movement and Metabolism: Exercise and Skeletal Muscle as Mediators of Health. A Report from the 26th Annual Harvard Nutrition Obesity Symposium, 2025.

Skeletal muscle is a crucial facilitator of many of the effects of exercise on metabolic health. Intrinsic myocellular mechanisms, exercise-induced myokine secretion, and crosstalk between multiple organ systems contribute to the maintenance of energy homeostasis, cardiovascular health, strength, cognition, and...

🗓️ 2026-03-12
📰 Publication: American Journal Of Clinical Nutrition
Read MoreMuscle Movement and Metabolism: Exercise and Skeletal Muscle as Mediators of Health. A Report from the 26th Annual Harvard Nutrition Obesity Symposium, 2025.

Muscle-immune metabolic crosstalk: shared pathways in cachexia and exercise.

Skeletal muscle and the immune system continuously exchange metabolites and signals that are essential for homeostasis. Disruption of this communication, such as during infection, inflammation, or cancer, triggers cachexia, a severe wasting syndrome characterized by altered amino acid flux, mitochondrial...

🗓️ 2026-02-21
📰 Publication: Current Opinion In Biotechnology
Read MoreMuscle-immune metabolic crosstalk: shared pathways in cachexia and exercise.

Multi-modal integrated intervention combining exercise, anti-inflammatory, and dietary advice (MMIEAD) for adults with kidney cachexia: protocol for a mixed-methods feasibility cluster randomised controlled trial and process evaluation.

BACKGROUND

Kidney cachexia is a debilitating and under-recognised complication of advanced chronic kidney disease (CKD), characterised by unintentional weight loss, muscle wasting, inflammation, and reduced functional capacity. Its profound impact on morbidity, quality of life, and healthcare utilisation underscores the need...

🗓️ 2026-02-20
Read MoreMulti-modal integrated intervention combining exercise, anti-inflammatory, and dietary advice (MMIEAD) for adults with kidney cachexia: protocol for a mixed-methods feasibility cluster randomised controlled trial and process evaluation.

Association of the "Weekend Warrior" Exercise Pattern With Sarcopenia in Middle-Aged and Older Adults: Comparison With Regular Activity and Inactivity Patterns.

PURPOSE

Although the "weekend warrior (WW)" physical activity (PA) pattern has known health benefits, its association with sarcopenia is unclear. This study examined whether the WW PA pattern is associated with a lower likelihood of sarcopenia compared with the inactive and...

🗓️ 2026-01-30
Read MoreAssociation of the "Weekend Warrior" Exercise Pattern With Sarcopenia in Middle-Aged and Older Adults: Comparison With Regular Activity and Inactivity Patterns.

HQ8: Do Nutritional Interventions Prevent the Onset and Progression of Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

🗓️ 2026-01-15
📰 Publication: Geriatrics & Gerontology International
Read MoreHQ8: Do Nutritional Interventions Prevent the Onset and Progression of Frailty in Older Adults?: English Translation of the Japanese Guideline for Digital Health for the Prevention and Improvement of Sarcopenia and Frailty.

Subscribe to the SCWD Newsletter

Stay Informed with the Latest Updates and Exclusive Insights!