Muscle_cells

Muscle

Pathways Contributing to Chemotherapy-Induced Myotoxicity Are Attenuated by EPA + DHA in a Clinically Relevant Model of Colorectal Cancer.

BACKGROUNDSkeletal muscle loss is a well-recognized consequence of cancer, and chemotherapy exacerbates myotoxicity through multiple mechanisms. Retaining muscle mass improves tumour response to therapies and tolerance to chemotherapy; hence, interventions to mitigate myotoxicity warrant investigations. This study aimed to investigate...

🗓️ 2025-11-17

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

cachexia / CELLS / chemotherapy / Colorectal_neoplasms / Diet / Drug_therapy / Fish_oils / Fluorouracil / Genes / Homeostasis / Leukocytes / Muscle_cells / Muscle,_skeletal / muscles / Myotoxicity / neoplasms / Sarcopenia / therapeutics

Muscle

Muscle Structure and Function Recovery: Adalimumab-Calcium Channel Synergy in Post-Ischemic Stroke Sarcopenia.

BACKGROUNDAdalimumab, a TNF-α inhibitor, is widely used clinically. Recent studies suggest Adalimumab can improve muscle damage after ischemic stroke (IS), but its protective mechanisms remain unclear. This study investigates the effect of adalimumab on muscle structure post-IS and the role...

🗓️ 2025-11-10

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Adalimumab / cachexia / Calcium / Calcium_channels / CELLS / Ischemic_stroke / Muscle_cells / Muscle_strength / Muscle_weakness / muscles / Recycling / Sarcopenia / therapeutics

Muscle

An Isogenic Human Myoblast Cell Model for Cystinosis Myopathy Reveals Alteration of Key Myogenic Regulatory Proteins.

BACKGROUNDCystinosis is a rare multisystem, autosomal recessive disease caused by dysfunction or loss of cystinosin (CTNS), which results in lysosomal cystine accumulation, primarily affecting the kidneys. Advances in renal transplantation, cysteamine treatment and improved medical care have increased life expectancy,...

🗓️ 2025-11-10

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

cachexia / CELLS / Cystine / Cystinosis / Metabolomics / Muscle_cells / Muscle_fibers,_skeletal / muscles / Muscular_diseases / Myoblasts / Sarcopenia / therapeutics

Muscle

Advancing Single-Cell Transcriptomic Analysis to Reveal Age-Related Skeletal Muscle Changes: A Systematic Review.

Population aging has become a widespread health problem that leads to huge socioeconomic burden. Skeletal muscle as an important component of motor system, gradually degenerates with age. Age-related muscle disorders, such as sarcopenia is associated with higher risks of falls,...

🗓️ 2025-10-24

📰 Publication: Aging And Disease

Aging / CELLS / Microscopy,_electron,_scanning_transmission / Muscle_cells / Muscle,_skeletal / muscles / Research / Sarcopenia / Schwann_cells / Stem_cells / therapeutics

Muscle

The Novel MuRF2 Target SNX5 Regulates PKA Activity Through Stabilization of RI-α and Controls Myogenic Differentiation.

BACKGROUNDMuscle RING finger (MuRF) proteins are striated muscle-specific E3 ubiquitin ligases essential for muscle homeostasis. Whereas MuRF1 is well known for its role in muscle atrophy, MuRF2 and MuRF3 contribute to microtubule stabilization, influencing muscle differentiation and function. Their cooperative...

🗓️ 2025-01-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

CELLS / Endosomes / Microtubules / Muscle_cells / muscles / Myostatin / Protein_isoforms / Sarcopenia / therapeutics / Ubiquitin / Ubiquitination

Muscle

Impact of Adipose Tissue and Lipids on Skeletal Muscle in Sarcopenia.

Although the decline in muscle mass, function and increased visceral obesity are attracting substantial attention in the ageing society, approved treatment modalities for sarcopenia/sarcopenic obesity (SO) remain limited. Elucidating effects and mechanisms of adipose tissue and lipids on skeletal muscle...

🗓️ 2025-01-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Adipose_tissue / Athletes / cachexia / CELLS / Insulin / Lipid_droplets / Muscle_cells / Muscle,_skeletal / muscles / Obesity / Organelle_biogenesis / Oxidative_stress / Sarcopenia / Stress,_physiological / therapeutics / tissues

Muscle

Late-Stage Skeletal Muscle Transcriptome in Duchenne Muscular Dystrophy Shows a BMP4-Induced Molecular Signature.

Duchenne muscular dystrophy (DMD) is a fatal X-linked recessive disease due to loss-of-function variants in the DYSTROPHIN gene. DMD-related skeletal muscle wasting is typified by an aberrant immune response involving upregulation of the TGFβ family of cytokines, like TGFβ1 and...

🗓️ 2025-08-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Biopsy / cachexia / CELLS / Genes / Muscle_cells / Muscle,_skeletal / muscles / Muscular_dystrophies / Muscular_dystrophy,_duchenne / Sarcopenia / Transcriptome / Up-regulation

Muscle

Scutellarein attenuates cancer cachexia-induced muscle atrophy via targeted inhibition of the JAK/STAT pathway.

Cancer cachexia is a multifaceted metabolic syndrome characterized by severe loss of skeletal muscle and adipose tissue, diminishing both quality of life and survival in cancer patients. Despite its prevalence, effective treatments for cancer cachexia remain limited. The JAK/STAT signaling...

🗓️ 2025-07-03

📰 Publication: Journal Of Advanced Research

cachexia / Cancer-associated_cachexia / CELLS / Muscle_cells / Muscle,_skeletal / muscles / Muscular_atrophy / neoplasms / therapeutics / tissues

Muscle

Early Detection of Age-Related Decline of Muscle Cell Mass by Intracellular Water Assessment Compared With MRI or DXA.

Ageing is commonly associated with a decrease in muscle strength, which is largely linked to decreases in skeletal muscle mass (SMM). The rate of the age-related decline in muscle strength is different from the rate of the age-related decline in...

🗓️ 2025-06-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

cachexia / CELLS / Muscle_cells / Muscle_strength / muscles / Muscular_atrophy / Respect / Sarcopenia

Muscle

Oestrogen Receptor Alpha in Myocyte Maintains Muscle Regeneration in Duchenne Muscular Dystrophy.

Oestrogen receptor alpha (ERα) plays an important role in maintaining mitochondrial function and regulating metabolism in skeletal muscle. However, its alterations and potential mechanisms in Duchenne muscular dystrophy (DMD) remain incompletely understood. In this study, we demonstrated the protective role...

🗓️ 2025-04-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

CELLS / Estradiol / Fulvestrant / Muscle_cells / Muscle,_skeletal / muscles / Muscular_dystrophies / Muscular_dystrophy,_duchenne / Myoblasts / Sarcopenia / therapeutics

Exercise

Electrospun microfibers to enhance nutrient supply in bioinks and 3D-bioprinted tissue precursors.

3D-bioprinting is a promising technique to mimic the complex anatomy of natural tissues, as it comprises a precise and gentle way of placing bioinks containing cells and hydrogel. Although hydrogels expose an ideal growth environment due to their extracellular matrix...

🗓️ 2024-12-11

📰 Publication: Biofabrication

2,2'-dipyridyl / 3-iodobenzylguanidine / 3,3'-diaminobenzidine / 3'_untranslated_regions / 5-methylcytosine / 5'_untranslated_regions / Abattoirs / Abdominal_muscles / Abdominal_neoplasms / Abdominal_pain / Abdominoplasty / Abortion,_spontaneous / Absenteeism / Absorption / Academic_medical_centers / Academic_performance / Accidental_falls / Accidents / Accounting / Acepromazine / Acetaldehyde / Acetals / Acetates / Acetylcholine / Acetylcholinesterase / Acetylcysteine / Acetylene / Acetylglucosamine / Acetyltransferases / Achievement / Acid_ceramidase / Acid_sensing_ion_channels / Acid-base_equilibrium / Acidosis / Acinetobacter / Acinetobacter_baumannii / Acne_vulgaris / Acoustics / Acquired_immunodeficiency_syndrome / Acromegaly / Acrylamide / Actins / Action_potentials / Activities_of_daily_living / Acute_care_surgery / Acute_coronary_syndrome / Acute_kidney_injury / Acute_lung_injury / Acyltransferases / Adaptation,_physiological / Adenocarcinoma_of_lung / Adenoma / 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Protein_isoforms / Protein_kinases / Protein_phosphatase_1 / Protein_processing,_post-translational / Protein_serine-threonine_kinases / Protein-tyrosine_kinases / Proteogenomics / Proteome / Proteomics / Prothrombin / Prothrombin_time / Proton_pump_inhibitors / Proton_pumps / Proton_therapy / Pruritus / Pseudogenes / Pseudomonas / Pseudomonas_aeruginosa / Pseudomonas_stutzeri / Pseudouridine / Psoriasis / Psychiatrists / Psychological_distress / Psychological_well-being / Psychology,_positive / Psychometrics / Psychosocial_intervention / Psychotherapy / Psychotic_disorders / Psychotropic_drugs / Public_health / Public_health_surveillance / Public_sector / Pulmonary_arterial_hypertension / Pulmonary_disease,_chronic_obstructive / Pulmonary_embolism / Pulmonary_fibrosis / Pulmonary_surfactant-associated_protein_a / Pulmonary_valve / Pulpectomy / Pulpotomy / Pulse / Punctures / Punishment / Pupa / Pupil / Purpura / Purpura,_thrombocytopenic / Putamen / Pyoderma / Pyoderma_gangrenosum / Pyrans / Pyrazoles / Pyridoxine / Pyrophosphatases / Pyroptosis / Pyrrolidinones / Pyruvate_kinase / Quadriceps_muscle / Qualitative_research / Quality_improvement / Quality_of_life / Quality-adjusted_life_years / Quantitative_trait_loci / Quantum_dots / Quarantine / Quercetin / Quinazolines / Quinoxalines / Quorum_sensing / Racism / Radar / Radiation_exposure / Radiation_fibrosis_syndrome / Radio / Radiofrequency_ablation / Radiography / Radiologists / Radiology / Radiology,_interventional / Radionuclide_imaging / radiotherapy / Radius_fractures / Rainforest / Random_allocation / Range_of_motion,_articular / Ranula / Rare_diseases / Reaction_time / Reading / Reading_frames / Receptor_activity-modifying_proteins / Receptor_for_advanced_glycation_end_products / Receptors,_adrenergic / Receptors,_antigen / Receptors,_antigen,_t-cell / Receptors,_calcitriol / Receptors,_cannabinoid / Receptors,_chemokine / Receptors,_chimeric_antigen / Receptors,_cxcr4 / Receptors,_estrogen / 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Exercise

A fluorescent aptasensor for deoxynivalenol detection based on Nb.BbvCI-assisted targeted-responsive three-way junctions integrated DNA walking machine.

Deoxynivalenol (DON) contamination in cereals is a widespread issue with global implications, necessitating the development of efficient detection methods. Here, a fluorescent aptasensor integrating target-responsive DNA three-way junction (TWJ) and DNA walking machine was developed to detect DON. The DON-specific...

🗓️ 2024-12-06

📰 Publication: Food Chemistry

1-phosphatidylinositol_4-kinase / 2-acetylaminofluorene / 3'_untranslated_regions / 5-hydroxytryptophan / Abdominal_pain / Abdominoplasty / Abetalipoproteinemia / Absenteeism / Absorption / Academic_performance / Accidental_falls / Accounting / Acetone / Acetylcholine / Achondroplasia / Acid_phosphatase / Acidosis,_renal_tubular / Acinetobacter_baumannii / Acitretin / Aconitic_acid / Acoustics / Acquired_immunodeficiency_syndrome / Acrylonitrile / Acute_kidney_injury / Acute_lung_injury / Adenocarcinoma / Adenocarcinoma_of_lung / Adenocarcinoma,_mucinous / Adenoidectomy / Adenoids / Adenomyosis / Adenosine / Adhesives / Adipocytes / Adipokines / Adipose_tissue / Adolescent / Adoptive_transfer / Adrenal_cortex_hormones / Adrenalectomy / Adrenocorticotropic_hormone / Aftercare / Agaricales / Aged / Ageism / Aggrecans / Aggression / Agricultural_irrigation / Agriculture / Aids-related_complex / Air_pollution / Airway_management / Alanine / Alcohol_drinking / Alcoholics / Alcoholism / Alginates / Algorithms / Alkaloids / Alkynes / Alleles / Allergens / Allografts / Alloys / Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic_acid / Alpha-fetoproteins / Alphapapillomavirus / Altitude / Alzheimer_disease / Amaranth_dye / Ambulances / Amino_acid_substitution / Amino_acids / Aminoglycosides / Amlodipine / Amnion / Amoxicillin / Amplifiers,_electronic / Amputation,_surgical / Amputees / Amygdala / Amyloid / Amyotrophic_lateral_sclerosis / Analgesics / Anaphylaxis / Anastomotic_leak / Anatomy / Androgens / Anemia / Anemia,_iron-deficiency / Anesthesia / Anesthesiology / Anesthetics / Aneurysm,_false / Angina_pectoris / Angina,_unstable / Angiogenesis / Angiogenesis_inhibitors / Angiotensins / Anion_exchange_resins / Ankle / Anoikis / Anorexia_nervosa / Anterior_chamber / Anthocyanins / Anthracyclines / Anthropometry / Anti-inflammatory_agents,_non-steroidal / Antibodies,_bispecific / Antibodies,_monoclonal / Anticoagulants / Anticonvulsants / Antifibrinolytic_agents / Antihypertensive_agents / Antimicrobial_stewardship / Antineoplastic_agents / Antioxidants / Antiphospholipid_syndrome / Antipsychotic_agents / Antitubercular_agents / Antiviral_agents / Aorta / Aortic_aneurysm / Aortic_aneurysm,_abdominal / Aortic_dissection / Aortic_valve / Aphasia / Aphasia,_primary_progressive / Apicoplasts / Apolipoproteins / Apoptosis / Apoptosis_regulatory_proteins / Appendiceal_neoplasms / Appendicitis / Appendix / Appetite / Arboviruses / Arenavirus / Arginine / Arrhythmias,_cardiac / Arteriovenous_malformations / Arthralgia / Arthritis / Arthritis,_rheumatoid / Arthroplasty / Arthroplasty,_replacement,_knee / Artificial_intelligence / Artificially_sweetened_beverages / Ascorbic_acid / Aspartate_aminotransferases / Aspartic_acid / Aspergillosis / Aspergillosis,_allergic_bronchopulmonary / Asthenozoospermia / Astrocytes / Astrocytoma / Astronauts / Ataxia / Ataxia_telangiectasia / Atherectomy / Atherosclerosis / Athletes / Atrasentan / Atrial_fibrillation / Atrophy / Attention_deficit_disorder_with_hyperactivity / Attentional_bias / Attitude_to_health / Audiology / Augmented_reality / Authorship / Autism_spectrum_disorder / Autistic_disorder / Autoantibodies / Autoimmune_diseases / Autophagy / Autopsy / Axial_spondyloarthritis / Axons / B-lymphocytes / Back_pain / Bacterial_adhesion / Bacteriocins / Bacteriophages / Balantidiasis / Bariatric_surgery / Bartonella / Base_sequence / Basement_membrane / Basophils / Beds / Begomovirus / Behcet_syndrome / Benzene / Benzimidazoles / Benzocaine / Bevacizumab / Bezafibrate / Bibliometrics / Bicuspid / Bicuspid_aortic_valve_disease / Bilirubin / Biochemistry / Biocompatible_materials / Biodiversity / Biofilms / Biogenic_amines / Biological_availability / Biological_factors / Biological_monitoring / Biological_oxygen_demand_analysis / Biological_therapy / Biomarkers / Biomass / Biomedical_research / Biomimetics / Biophysics / Biopolymers / Biopsy / Biosimilar_pharmaceuticals / Biostatistics / 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Ischemia / Ischemic_preconditioning / Ischemic_stroke / Islet_amyloid_polypeptide / Isocitrate_dehydrogenase / Ivermectin / Janus_kinase_inhibitors / Jaundice / Jaundice,_neonatal / Jejunum / Joint_dislocations / Junctional_adhesion_molecule_c / Jurisprudence / Kanamycin / Kelp / Keratitis / Keratoconus / Ketamine / Ketosis / Kidney / Kidney_failure,_chronic / Kidney_neoplasms / Kidney_transplantation / Killer_cells,_natural / Kynurenic_acid / Kynurenine / Laboratories / Lacerations / Lactams / Lactic_acid / Lactobacillus / Lactones / Landslides / Language / Laparoscopy / Larva / Laryngeal_neoplasms / Laser_therapy / Lasers / Latent_infection / Latent_tuberculosis / Laxatives / Learning_disabilities / Lecithins / Length_of_stay / Leptospirosis / Lethargy / Leucine / Leukemia / Leukemia,_myeloid / Leukemia,_myeloid,_acute / Leukocyte_l1_antigen_complex / Lichen_sclerosus_et_atrophicus / Lichens / Lidocaine / Life_expectancy / Life_style / Ligaments / Ligands / Ligation / Lignin / Limit_of_detection / Limonene / Linagliptin / Linguistics / Lipid_droplets / Lipid_metabolism_disorders / Lipid_nanoparticles / Lipid_peroxides / Lipopolysaccharides / Lipoprotein(a) / Lipoproteins / Liposarcoma / Liquid_biopsy / Liquid_crystals / Lithiasis / Live_birth / Liver_cirrhosis / Liver_failure / Liver_failure,_acute / Liver_neoplasms / Liver_transplantation / Local_area_networks / Locomotion / Longevity / Longitudinal_studies / Lordosis / Low_back_pain / Low_tension_glaucoma / Lubiprostone / Luciferases / Lung / Lung_diseases / Lung_diseases,_interstitial / Lung_diseases,_obstructive / Lung_injury / Lung_neoplasms / Lupus_erythematosus,_systemic / Luteal_phase / Lyme_disease / Lymph_nodes / Lymphatic_diseases / Lymphatic_system / Lymphedema / Lymphocytes / Lymphocytes,_tumor-infiltrating / Lymphohistiocytosis,_hemophagocytic / Lymphoma / Lymphoma,_b-cell / Lymphoma,_follicular / Lymphoma,_large_b-cell,_diffuse / Lymphoma,_t-cell / Lymphoma,_t-cell,_peripheral / Lysine / Lysophosphatidylcholines / Lysosomes / Machine_learning / Macrophages / Macrophages,_alveolar / Magnetic_resonance_imaging / Maintenance / Malnutrition / Mammaplasty / Mannans / Mannitol / Mannose-binding_lectin / Mannosyltransferases / Margins_of_excision / Marijuana_use / Marketing / Masculinity / Masks / Mast_cells / Mastitis / Mastitis,_bovine / Mastoiditis / Maternal_mortality / Mathematics / Meals / Meat / Mechanistic_target_of_rapamycin_complex_1 / Medial_tibial_stress_syndrome / Mediation_analysis / Medical_laboratory_science / Medical_marijuana / Medical_oncology / Medical_records / Medical_staff / Medical_waste / Medicare / Medication_adherence / Medication_errors / Medicine,_chinese_traditional / Medicine,_traditional / Meditation / Medulloblastoma / Melanins / Melanoma / Meloxicam / Membrane_proteins / Membranes / Memory / Menarche / Mendelian_randomization_analysis / Meninges / Meningioma / Meningitis / Menstruation / Mental_disorders / Mental_health / Mental_health_services / Menthol / Mentoring / Mesalamine / Mesangial_cells / Mesencephalon / Mesenchymal_stem_cells / Metabolic_diseases / Metabolic_equivalent / Metabolic_syndrome / Metabolomics / Metagenomics / Metal-organic_frameworks / Metastasectomy / Metformin / Methanol / Methemoglobin / Methemoglobinemia / Methicillin / Methotrexate / Methylphenidate / Methylprednisolone / Metronidazole / Metschnikowia / Micelles / Microbial_interactions / Microbiology / Microfluidics / Micronutrients / Micrornas / Microsatellite_repeats / Microscopic_polyangiitis / MICROSCOPY / Microscopy,_electron,_scanning_transmission / Microscopy,_electron,_transmission / Microspheres / Middle_cerebral_artery / Migraine_disorders / Military_personnel / Milk / Milk,_human / Mineralocorticoids / Miniaturization / Minimally_invasive_surgical_procedures / Mitochondria / Mitochondrial_dynamics / Mixed_function_oxygenases / Models,_statistical / Molecular_biology / Molecular_dynamics_simulation / Monocytes / Monophenol_monooxygenase / Morphine / Morris_water_maze_test / MORTALITY / Mosaic_viruses / Mothers / Motivation / Motivational_interviewing / Motor_activity / Mouth / Mouth_neoplasms / Movement / Moxibustion / Mucosa-associated_lymphoid_tissue_lymphoma_translocation_1_protein / Mucous_membrane / Multimodal_imaging / Multiparametric_magnetic_resonance_imaging / Multiple_chronic_conditions / Multiple_myeloma / Multiple_sclerosis / Multiple_sclerosis,_relapsing-remitting / Multivariate_analysis / Muscle_cells / Muscle_spasticity / Muscle_strength / Muscle,_skeletal / Muscle,_smooth / muscles / Muscular_dystrophies / Muscular_dystrophy,_duchenne / Musculoskeletal_diseases / Musculoskeletal_system / Mutagenesis / Mutation / Mutation,_missense / Myalgia / Mycobacterium / Mycoses / Myeloid_cells / Myeloid-derived_suppressor_cells / Myoblasts / Myoblasts,_skeletal / Myocardial_infarction / Myocardium / Myocytes,_cardiac / Myocytes,_smooth_muscle / Myofibroblasts / Myokymia / Myoma / Myopia / 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The Journal of Cachexia, Sarcopenia & Muscle ⟶

Muscle_cells

Pathways Contributing to Chemotherapy-Induced Myotoxicity Are Attenuated by EPA + DHA in a Clinically Relevant Model of Colorectal Cancer.

Muscle Structure and Function Recovery: Adalimumab-Calcium Channel Synergy in Post-Ischemic Stroke Sarcopenia.

An Isogenic Human Myoblast Cell Model for Cystinosis Myopathy Reveals Alteration of Key Myogenic Regulatory Proteins.

Advancing Single-Cell Transcriptomic Analysis to Reveal Age-Related Skeletal Muscle Changes: A Systematic Review.

The Novel MuRF2 Target SNX5 Regulates PKA Activity Through Stabilization of RI-α and Controls Myogenic Differentiation.

Impact of Adipose Tissue and Lipids on Skeletal Muscle in Sarcopenia.

Late-Stage Skeletal Muscle Transcriptome in Duchenne Muscular Dystrophy Shows a BMP4-Induced Molecular Signature.

Scutellarein attenuates cancer cachexia-induced muscle atrophy via targeted inhibition of the JAK/STAT pathway.

Early Detection of Age-Related Decline of Muscle Cell Mass by Intracellular Water Assessment Compared With MRI or DXA.

Oestrogen Receptor Alpha in Myocyte Maintains Muscle Regeneration in Duchenne Muscular Dystrophy.

Electrospun microfibers to enhance nutrient supply in bioinks and 3D-bioprinted tissue precursors.

A fluorescent aptasensor for deoxynivalenol detection based on Nb.BbvCI-assisted targeted-responsive three-way junctions integrated DNA walking machine.

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