Due to increasing older populations worldwide, injuries, disabilities and deaths caused by falls among the elderly represent a growing human and societal problem. We aimed to improve health among men of at least 70ย years of age with low-normal to low...
๐๏ธ 2024-06-18
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Intensive care unit-acquired weakness (ICU-AW) is a syndrome characterized by a long-term muscle weakness often observed in sepsis-surviving patients during the chronic phase. Although ICU-AW is independently associated with increased mortality, effective therapies have yet to be established. Programmed death-1...
๐๏ธ 2024-07-17
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Chronic subdural haematoma (CSDH) drainage is a common neurosurgical procedure. CSDHs cause excess mortality, which is exacerbated by frailty. Sarcopenia contributes to frailty - its key component, low muscle mass, can be assessed using cross-sectional imaging. We aimed to examine...
๐๏ธ 2024-05-08
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Cross-sectional evidence suggests a possible link between frailty and atrial fibrillation (AF). It remains unclear whether frailty and incident arrhythmias are longitudinally associated. This study aimed to determine whether the frailty phenotype is longitudinally associated with incident arrhythmias, especially AF....
๐๏ธ 2024-06-09
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
The effects of post-coronavirus disease 2019 (COVID-19) syndrome on the cardiorespiratory and muscular fitness in older people are of utmost relevance. This study aimed to evaluate the effects of a 12-week telerehabilitation programme on cardiorespiratory and muscular fitness and body...
๐๏ธ 2024-06-27
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
The association between the adiponectin-to-leptin ratio (A/L ratio) and the risk of incident chronic kidney disease (CKD) is poorly understood. This study aimed to investigate the association between A/L ratio and the risk of incident CKD and to examine whether...
๐๏ธ 2024-04-17
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
The way physical activity (PA) and sedentary behaviour (SB) independently and interactively modify the age-related decline in physical capacity remains poorly understood. This cross-sectional study investigated the independent and interactive associations of PA and SB with physical function and performance...
๐๏ธ 2024-04-18
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Increasing interest surrounds the utility of blood-based biomarkers for diagnosing sarcopenia. C-terminal agrin fragment (CAF), a marker of neuromuscular junction stability, is amongst the most promising candidates; however, a dearth of reference data impedes the incorporation of its use in...
๐๏ธ 2024-06-07
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Mitochondria represent key organelles influencing cellular homeostasis and have been implicated in the signalling events regulating protein synthesis. We examined whether mitochondrial bioenergetics (oxidative phosphorylation and reactive oxygen species (HO) emission, ROS) measured in vitro in permeabilized muscle fibres represent...
๐๏ธ 2024-07-15
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
The importance of preoperative physical function assessment for post-operative intervention has been reported in older patients undergoing cardiovascular surgery. Phase angle (PhA), measured using bioelectrical impedance analysis, is an indicator of cellular health and integrity and is reported as a...
๐๏ธ 2024-06-10
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Alzheimer's disease (AD) impairs cognitive functions and peripheral systems, including skeletal muscles. The PS19 mouse, expressing the human tau P301S mutation, shows cognitive and muscular pathologies, reflecting the central and peripheral atrophy seen in AD. We analysed skeletal muscle morphology...
๐๏ธ 2024-04-22
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Lean body mass (LBM) and the functional capacity of cardiovascular (CV) and respiratory systems constitute a female-specific relationship in European-American individuals. Whether this recent finding be extrapolated to the world's largest ethnic group, that is, Hans Chinese (HC, a population...
๐๏ธ 2024-04-17
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Body weight and its changes have been associated with cancer outcomes. However, the associations of short-term peridiagnosis weight dynamics in standardized, clinically operational time frames with cancer survival remain largely unknown. This study aimed to screen for and evaluate the...
๐๏ธ 2024-04-21
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Muscle atrophy can cause muscle dysfunction and weakness. Krรผppel-like factor 13 (KLF13), a central regulator of cellular energy metabolism, is highly expressed in skeletal muscles and implicated in the pathogenesis of several diseases. This study investigated the role of KLF13...
๐๏ธ 2024-07-08
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Low skeletal muscle mass (LSMM) and/or, function associated with an increased risk of treatment-related toxicities and inferior overall survival (OS) among adults with solid malignancies. However, the association between LSMM and treatment-related toxicities among adults with haematologic malignancies remains unclear....
๐๏ธ 2024-04-01
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
Loss of muscle strength and endurance with aging or in various conditions negatively affects quality of life. Resistance exercise training (RET) is the most powerful means to improve muscle mass and strength, but it does not generally lead to improvements...
๐๏ธ 2024-06-16
๐ฐ Publication: Journal Of Cachexia Sarcopenia And Muscle
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