Reconsidering the role of active vitamin D in preventing sarcopenia: Letter to the editor.
📰 Journal: Metabolism-Clinical And Experimental
Read MoreReconsidering the role of active vitamin D in preventing sarcopenia: Letter to the editor.SCWD Publications Digest
Staying informed on the latest in cachexia, sarcopenia, and wasting disorders research is essential yet challenging. The SCWD Digest offers concise updates and expert insights into significant studies and developments. We highlight and link directly to leading research, making it easier for healthcare professionals to access and apply groundbreaking findings. Our goal: empower the medical community to advance patient care worldwide efficiently.
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MG53 deficiency mediated skeletal muscle dysfunction in chronic obstructive pulmonary disease via impairing mitochondrial fission.
Myokine dysregulation and mitochondrial dysfunction are implicated in the pathogenesis of sarcopenia in chronic obstructive pulmonary disease. The objective of this study is to explore the role of myokines and mitochondrial dysfunction in sarcopenia in chronic obstructive pulmonary disease. We...
📰 Journal: Redox Biology
Read MoreMG53 deficiency mediated skeletal muscle dysfunction in chronic obstructive pulmonary disease via impairing mitochondrial fission.The potential of TAOK1 as a new therapeutic target for the treatment of cancer cachexia-associated muscle atrophy.
Cancer cachexia, a multifactorial metabolic syndrome impacts 50-80% cancer patients, is mainly characterized by skeletal muscle atrophy. In this study, we demonstrated that the thousand-and-one amino acid kinase 1 (TAOK1) was activated in both C2C12 myotubes treated with simulated cancer...
📰 Journal: Pharmacological Research
Read MoreThe potential of TAOK1 as a new therapeutic target for the treatment of cancer cachexia-associated muscle atrophy.The role of active vitamin D in preventing sarcopenia-Authors' reply.
📰 Journal: Metabolism-Clinical And Experimental
Read MoreThe role of active vitamin D in preventing sarcopenia-Authors' reply.Association between cumulative pack-year smoking exposure and sarcopenia: a KoGES cohort study.
Sarcopenia is the age-related involuntary loss of skeletal muscle mass and strength. Many factors, such as ageing and behaviour, may affect the risk of sarcopenia. However, no study had confirmed the association between cumulative exposure to smoking and the risk...
📰 Journal: International Journal Of Epidemiology
Read MoreAssociation between cumulative pack-year smoking exposure and sarcopenia: a KoGES cohort study.Prevalence of sarcopenia in middle-aged and older adults with cognitive impairment: a meta-analysis.
Cognitive impairment, dementia and sarcopenia significantly reduce the quality of life in middle-aged and older adults by impairing daily functioning, making cognitive decline a major concern for healthcare professionals. To estimate the prevalence of sarcopenia and probable sarcopenia in middle-aged...
📰 Journal: Age And Ageing
Read MorePrevalence of sarcopenia in middle-aged and older adults with cognitive impairment: a meta-analysis.Artificial Intelligence in the Management of Malnutrition in Cancer Patients: A Systematic Review.
Malnutrition is a critical complication among cancer patients, affecting up to 80% of individuals depending on cancer type, stage, and treatment. Artificial Intelligence (AI) has emerged as a promising tool in healthcare, with potential applications in nutritional management to improve...
Comment on "Reduced temporal muscle thickness predicts shorter survival in patients undergoing chronic subdural haematoma drainage" by Korhonen et al.-The authors' reply.
📰 Journal: Journal Of Cachexia Sarcopenia And Muscle
Read MoreComment on "Reduced temporal muscle thickness predicts shorter survival in patients undergoing chronic subdural haematoma drainage" by Korhonen et al.-The authors' reply.Sarcopenia in heart failure: Comparison of prognostic value between the Asian working Group for Sarcopenia 2014 and 2019 criteria.
Sarcopenia is a prevalent comorbidity among older patients with heart failure. This study aimed to evaluate the differences between sarcopenia diagnosed using the Asian Working Group for Sarcopenia (AWGS) 2014 and 2019 criteria in older patients with heart failure. This...
📰 Journal: Geriatrics & Gerontology International
Read MoreSarcopenia in heart failure: Comparison of prognostic value between the Asian working Group for Sarcopenia 2014 and 2019 criteria.Longitudinal Associations Between Baseline Sarcopenia and Knee Osteoarthritis Progression and Risk of Knee Replacement.
Sarcopenia and knee osteoarthritis (KOA) are common conditions in older adults, but the relationship is controversial. We aimed to examine the potential role of sarcopenia in KOA progression and subsequent knee replacement (KR). Using data from the Osteoarthritis Initiative (OAI),...
📰 Journal: Arthritis & Rheumatology
Read MoreLongitudinal Associations Between Baseline Sarcopenia and Knee Osteoarthritis Progression and Risk of Knee Replacement.Stool Microbiome Features and Weight Change Response to Treatment for cancer cachexia.
Cancer cachexia is characterised by significant weight loss and muscle wasting that adversely affects patient outcomes. Nutritional interventions in cancer cachexia leads to improved outcomes, including improved weight change. However, there are wide variations in weight response to dietary interventions....
📰 Journal: Journal Of Cachexia Sarcopenia And Muscle
Read MoreStool Microbiome Features and Weight Change Response to Treatment for cancer cachexia.The extract of chrysanthemum flos mitigates post-stroke sarcopenia by inhibiting PANoptosis and restoring muscle homeostasis.
Sarcopenia and muscle weakness are prevalent complications of ischemic stroke (IS), with limited pharmacological options. This study identifies high-dose extracts of Chrysanthemum Flos (ECF) as a potential therapy for post-stroke muscle dysfunction by targeting PANoptosis-a pro-inflammatory programmed cell death pathway....
📰 Journal: Phytomedicine
Read MoreThe extract of chrysanthemum flos mitigates post-stroke sarcopenia by inhibiting PANoptosis and restoring muscle homeostasis.Sarcopenic obesity defined by Japanese Working Group on Sarcopenic Obesity in post-stroke inpatients: prevalence and clinical implications.
Sarcopenic obesity (SO) is characterized by the coexistence of sarcopenia and obesity, associated with adverse health outcomes. This study aimed to investigate the prevalence of SO as defined by the recently published Japanese Working Group on Sarcopenic Obesity (JWGSO) criteria...
Impact of physical activities in metabolic dysfunction associated steatotic liver disease, sarcopenia, and cardiovascular disease.
There are no comprehensive studies that investigated differential effects of physical activity (PA) types on metabolic dysfunction associated steatotic liver disease (MASLD) and their associations with sarcopenia and cardiovascular disease. A cross-sectional analysis using data from 66,021 participants from the...
📰 Journal: Diabetes Research And Clinical Practice
Read MoreImpact of physical activities in metabolic dysfunction associated steatotic liver disease, sarcopenia, and cardiovascular disease.Integrated Multiomics Analyses of the Molecular Landscape of Sarcopenia in Alcohol-Related Liver Disease.
Skeletal muscle is a major target for ethanol-induced perturbations, leading to sarcopenia in alcohol-related liver disease (ALD). The complex interactions and pathways involved in adaptive and maladaptive responses to ethanol in skeletal muscle are not well understood. Unlike hypothesis-driven experiments,...
📰 Journal: Journal Of Cachexia Sarcopenia And Muscle
Read MoreIntegrated Multiomics Analyses of the Molecular Landscape of Sarcopenia in Alcohol-Related Liver Disease.Myosteatosis as a New Risk Factor of Surgical Complications in Kidney Transplant Recipients: A Retrospective Study.
Computed tomography (CT) scan-defined myosteatosis is a common feature in ESKD patients receiving kidney transplantation (KT) and is associated with mortality after KT. We aimed to explore the impact of myosteatosis and other CT scan based morphometric data on the...
📰 Journal: Journal Of Cachexia Sarcopenia And Muscle
Read MoreMyosteatosis as a New Risk Factor of Surgical Complications in Kidney Transplant Recipients: A Retrospective Study.