Concurrent PIK3CA mutant promotes cachexia through inflammatory signaling in EGFR mutant lung cancer.
PIK3CA mutation is frequently concurrent with known oncogenic drivers such as EGFR mutation in lung cancer, raising an interesting question about its real function. Cachexia is a systemic disease arising from tumor-organ crosstalk, significantly contributing to cancer-related mortality. Through integrative...
🗓️ 2025-12-16
📰 Publication: Nature Communications
Read MoreConcurrent PIK3CA mutant promotes cachexia through inflammatory signaling in EGFR mutant lung cancer.