Apoptosis

Muscle

The mitochondrial-targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial-apoptotic but not necroptotic signalling during ovarian cancer.

The degree to which mitochondrial-linked programmed cell death pathways contribute to skeletal muscle atrophy during cancer remains unknown. Here we combined a novel and robust mouse model of metastatic ovarian cancer with chronic administration of the mitochondrial-targeted antioxidant SkQ1 to...

🗓️ 2025-11-03

📰 Publication: Journal Of Physiology-London

Antioxidants / Apoptosis / cachexia / Caspase_9 / Caspases / Cell_death / CELLS / Mitochondria / Muscle,_skeletal / muscles / Muscular_atrophy / Necroptosis / neoplasms / Ovarian_neoplasms / Physiology

Sarcopenia

Therapeutic Targeting of Decr1 Ameliorates Cardiomyopathy by Suppressing Mitochondrial Fatty Acid Oxidation in Diabetic Mice.

A significant increase in mitochondrial fatty acid oxidation (FAO) is now increasingly recognized as one of the metabolic alterations in diabetic cardiomyopathy (DCM). However, the molecular mechanisms underlying mitochondrial FAO impairment in DCM remain to be fully elucidated. A type...

🗓️ 2025-04-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Apoptosis / Cardiomyopathies / Diabetes_mellitus / Fatty_acids / Hypertrophy / Mitochondria / Myocytes,_cardiac / Oxidative_stress / Oxidoreductases / therapeutics

Muscle

Melatonin Ameliorates Age-Related Sarcopenia via the Gut-Muscle Axis Mediated by Serum Lipopolysaccharide and Metabolites.

Sarcopenia affects the quality of life and increases adverse outcomes in the elderly. However, as a potential safe and effective remedy to many age-related disorders, little is known about the protective effect of melatonin against sarcopenia, especially the underlying mechanisms...

🗓️ 2025-02-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Aged / Apoptosis / Caspase_8 / Caspases / Gastrointestinal_microbiome / Lipopolysaccharides / Mediation_analysis / Melatonin / Microbiota / Muscle_strength / Muscle,_skeletal / muscles / Sarcopenia / SERUM

Exercise

Electrospun microfibers to enhance nutrient supply in bioinks and 3D-bioprinted tissue precursors.

3D-bioprinting is a promising technique to mimic the complex anatomy of natural tissues, as it comprises a precise and gentle way of placing bioinks containing cells and hydrogel. Although hydrogels expose an ideal growth environment due to their extracellular matrix...

🗓️ 2024-12-11

📰 Publication: Biofabrication

2,2'-dipyridyl / 3-iodobenzylguanidine / 3,3'-diaminobenzidine / 3'_untranslated_regions / 5-methylcytosine / 5'_untranslated_regions / Abattoirs / Abdominal_muscles / Abdominal_neoplasms / Abdominal_pain / Abdominoplasty / Abortion,_spontaneous / Absenteeism / Absorption / Academic_medical_centers / Academic_performance / Accidental_falls / Accidents / Accounting / Acepromazine / Acetaldehyde / Acetals / Acetates / Acetylcholine / Acetylcholinesterase / Acetylcysteine / Acetylene / Acetylglucosamine / Acetyltransferases / Achievement / Acid_ceramidase / Acid_sensing_ion_channels / Acid-base_equilibrium / Acidosis / Acinetobacter / Acinetobacter_baumannii / Acne_vulgaris / Acoustics / Acquired_immunodeficiency_syndrome / Acromegaly / Acrylamide / Actins / Action_potentials / Activities_of_daily_living / Acute_care_surgery / Acute_coronary_syndrome / Acute_kidney_injury / Acute_lung_injury / Acyltransferases / Adaptation,_physiological / Adenocarcinoma_of_lung / Adenoma / Adenoma,_pleomorphic / Adenomyosis / Adenosine / Adhesives / Adipocytes / Adipocytes,_brown / Adipocytes,_white / Adipogenesis / Adiponectin / Adipose_tissue / Adiposity / Administration,_intranasal / Administration,_oral / Adolescent / Adrenal_cortex_hormones / Adrenocorticotropic_hormone / Adult_stem_cells / Advance_care_planning / Adverse_childhood_experiences / Advertising / Aeromonas_veronii / Aerosols / Aflatoxin_m1 / Aflatoxins / African_swine_fever / Aftercare / Agar / Agaricales / Age_distribution / Aged / Agent_orange / Aggregatibacter / Aggregatibacter_aphrophilus / Aggression / Aging,_premature / Agranulocytosis / Agricultural_irrigation / Agriculture / Agrochemicals / Aids-related_complex / Air_pollution / Alanine / Alcohol_drinking / Alcoholics / Aldehydes / Aldosterone / Alendronate / Alginates / Algorithms / Alkaline_phosphatase / Alkalosis / Alkanesulfonates / Alkynes / Alleles / Allergens / Allografts / Allopurinol / Alloys / Alopecia / Alopecia_areata / Alpha_1-antitrypsin / Alpha_1-antitrypsin_deficiency / Alpha-glucosidases / Alpha-linolenic_acid / Alpha-synuclein / Alphapapillomavirus / Altitude / Alzheimer_disease / Amanita / Ambulances / Ambulatory_care / Ambulatory_care_facilities / Amikacin / Amine_oxidase_(copper-containing) / Amines / Amino_acid_sequence / Amino_acid_substitution / Amino_acids / Amino_acids,_branched-chain / Amino_acids,_sulfur / Amino_alcohols / Aminolevulinic_acid / Amlodipine / Amoxicillin / Amphetamines / Amphotericin_b / Amplifiers,_electronic / Amputation,_surgical / Amputees / Amygdala / Amyloid / Amyloidosis / Amylopectin / Amyotrophic_lateral_sclerosis / Analgesia / Analgesics / Analysis_of_variance / Anaphylaxis / Anastomotic_leak / Anemia / Anemia,_aplastic / Anemia,_iron-deficiency / Anemia,_sickle_cell / Anesthesia / Anesthesia,_conduction / Anesthesia,_epidural / Anesthesia,_intravenous / Anesthesia,_local / Anesthesia,_obstetrical / Anesthesiologists / Anesthesiology / Anesthetics / 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Blindness / BLOOD / Blood_cell_count / Blood_cells / Blood_circulation / Blood_coagulation_factors / Blood_component_removal / Blood_culture / Blood_donors / Blood_glucose / Blood_platelets / Blood_pressure / Blood_pressure_monitoring,_ambulatory / Blood_substitutes / Blood_transfusion,_intrauterine / Blood_urea_nitrogen / Blood_vessels / Blood_volume / Blotting,_western / Body_composition / Body_contouring / Body_image / Body_mass_index / Body_size / Body_weight / Bone_cements / Bone_cysts / Bone_diseases / Bone_marrow / Bone_neoplasms / Bone_regeneration / Bone_transplantation / Bony_callus / Borates / Botany / Botulinum_toxins / Botulinum_toxins,_type_a / Botulism / Bowen's_disease / Bradycardia / Bradykinin / Brain / Brain_diseases / Brain_injuries / Brain_injuries,_traumatic / Brain_ischemia / Brain_stem / Brain_stem_infarctions / Bread / Breast / Breast_cancer_lymphedema / Breast_feeding / Breast_neoplasms / Bronchiectasis / Bronchiolitis_obliterans_syndrome / Bronchitis / Bronchogenic_cyst / Bronchopulmonary_sequestration / Bronchoscopy / Brucella / Brucellosis / Brugada_syndrome / Budesonide / Buffers / Bulimia / Bundle-branch_block / Bupropion / Burning_mouth_syndrome / Burnout,_psychological / Burns / Butter / Butyrylcholinesterase / C-peptide / C-reactive_protein / Ca-19-9_antigen / cachexia / Caco-2_cells / Cadherins / Caffeine / Calcitonin_gene-related_peptide / Calcium / Calcium_channel_blockers / Calcium_channels / Calcium_signaling / Cancer_vaccines / Cancer-associated_cachexia / Cancer-associated_fibroblasts / Candidemia / Candidiasis / Candidiasis,_invasive / Candidiasis,_vulvovaginal / Cannabidiol / Cannula / Capacity_building / Capillaries / Capsaicin / Capsid / Capsules / Car-t_cell / Carbamazepine / Carbapenems / Carbidopa / Carbohydrates / Carboxylic_acids / Carcinogenesis / Carcinogens / Carcinoid_tumor / Carcinoma_in_situ / Carcinoma,_basal_cell / Carcinoma,_hepatocellular / Carcinoma,_intraductal,_noninfiltrating / Carcinoma,_non-small-cell_lung / Carcinoma,_ovarian_epithelial / Carcinoma,_renal_cell / Carcinoma,_squamous_cell / Cardiac_catheters / Cardiac_output / Cardiac_rehabilitation / Cardiac_resynchronization_therapy / Cardiac_volume / Cardiology / Cardiomyopathy,_restrictive / Cardiopulmonary_bypass / Cardiopulmonary_resuscitation / Cardiotoxicity / Cardiovascular_diseases / Cardiovascular_system / Caregivers / Carotenoids / Carotid_arteries / Carotid_artery,_internal / Carrier_proteins / Case-control_studies / Caseins / Caspase_3 / Caspase_9 / Caspases / Castleman_disease / Castration / Catalase / Cataract / Catastrophization / Catechin / Catechol_o-methyltransferase / Catecholamines / Catenins / Catheter_ablation / Catheterization / Causality / Caveolins / Cecum / Cefazolin / Cefoperazone / Cefotaxime / Ceftazidime / Ceftriaxone / Celiac_disease / Cell_aggregation / Cell_biology / Cell_body / Cell_communication / Cell_count / Cell_culture_techniques / Cell_cycle / Cell_death / 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Chemokine_cx3cl1 / Chemokine_cxcl12 / Chemokines / Chemokines,_cxc / Chemoprevention / Chemoradiotherapy / Chemotherapy,_adjuvant / Chest_pain / Chick_embryo / Chickenpox / Chikungunya_virus / Child_abuse,_sexual / Child_custody / Child_development / Child_health / Child_health_services / Child,_hospitalized / Child,_preschool / Chimera / Chimerism / Chitin / Chitosan / Chlamydia / Chloramphenicol / Chlorogenic_acid / Chlorophyll / Chlorophyll_a / Chloroplasts / Chlortetracycline / Cholangiocarcinoma / Cholangiography / Cholangitis / Cholecalciferol / Cholecystectomy / Cholecystitis / Cholecystitis,_acute / Choledocholithiasis / Cholera / Cholestasis / Cholestasis,_intrahepatic / Cholesterol / Cholesterol_esters / Cholesterol,_hdl / Cholesterol,_ldl / Cholinergic_agents / Chondrocytes / Chondrogenesis / Chondroitin / Chondroitin_sulfates / Chordoma / Chorea / Chorioamnionitis / Chromatin / Chromatin_immunoprecipitation / Chromogranin_a / Chromogranins / Chromosome_aberrations / Chronic_disease / Chronic_pain / Chylothorax / Chylous_ascites / Cicatrix / Cilia / Ciprofloxacin / Circadian_clocks / Circovirus / Circulating_microrna / Circulating_tumor_dna / Citalopram / Citizen_science / Citric_acid / Citrinin / Citrobacter / Citrobacter_rodentium / Citrulline / Cladribine / Classical_swine_fever / Clathrin / Clay / Climacteric / Climate / Clinical_alarms / Clinical_decision-making / Clinical_laboratory_techniques / Clitoris / Clobazam / Clone_cells / Clonidine / Clostridioides / Clostridioides_difficile / Clostridium / Cloud_computing / Clozapine / Cluster_analysis / Clustered_regularly_interspaced_short_palindromic_repeats / Clutch_size / Coagulase / Coal / Coal_industry / Coccidioidomycosis / Cochlear_implants / Cochlear_nucleus / Coconut_oil / Codon / Coffee / Cognition_disorders / Cognitive_behavioral_therapy / Cognitive_dissonance / Cognitive_dysfunction / Cognitive_restructuring / Cognitive_training / Cohort_studies / Coinfection / Colchicine / 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Epilepsies,_partial / Epilepsy / Epilepsy,_absence / Epilepsy,_temporal_lobe / Episiotomy / Epithelial_cells / Epithelial-mesenchymal_transition / Epithelium,_corneal / Erythrocyte_transfusion / Erythrocytes / Erythropoietin / Escherichia_coli / Esophageal_fistula / Esophageal_neoplasms / Esophageal_sphincter,_lower / Esophageal_squamous_cell_carcinoma / Esophagectomy / Esophagogastric_junction / Esophagus / Estrus_detection / Ether / Ethics / Ethics,_medical / Ethmoid_sinus / Ethylene_glycol / Ethylene_oxide / Etomidate / European_union / Evolution,_molecular / Exanthema / Excitation_contraction_coupling / Executive_function / Exercise_test / Exercise_therapy / Exome / Exome_sequencing / Exons / Exosomes / Explosive_agents / External_fixators / Extracellular_matrix / Extracellular_vesicles / Extracorporeal_membrane_oxygenation / Extreme_weather / Eye / Eye_diseases / Eye_movements / Eyeglasses / Eyelids / Facial_expression / Facial_paralysis / Facial_recognition / Factor_viii / 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Exercise

A fluorescent aptasensor for deoxynivalenol detection based on Nb.BbvCI-assisted targeted-responsive three-way junctions integrated DNA walking machine.

Deoxynivalenol (DON) contamination in cereals is a widespread issue with global implications, necessitating the development of efficient detection methods. Here, a fluorescent aptasensor integrating target-responsive DNA three-way junction (TWJ) and DNA walking machine was developed to detect DON. The DON-specific...

🗓️ 2024-12-06

📰 Publication: Food Chemistry

1-phosphatidylinositol_4-kinase / 2-acetylaminofluorene / 3'_untranslated_regions / 5-hydroxytryptophan / Abdominal_pain / Abdominoplasty / Abetalipoproteinemia / Absenteeism / Absorption / Academic_performance / Accidental_falls / Accounting / Acetone / Acetylcholine / Achondroplasia / Acid_phosphatase / Acidosis,_renal_tubular / Acinetobacter_baumannii / Acitretin / Aconitic_acid / Acoustics / Acquired_immunodeficiency_syndrome / Acrylonitrile / Acute_kidney_injury / Acute_lung_injury / Adenocarcinoma / Adenocarcinoma_of_lung / Adenocarcinoma,_mucinous / Adenoidectomy / Adenoids / Adenomyosis / Adenosine / Adhesives / Adipocytes / Adipokines / Adipose_tissue / Adolescent / Adoptive_transfer / Adrenal_cortex_hormones / Adrenalectomy / Adrenocorticotropic_hormone / Aftercare / Agaricales / Aged / Ageism / Aggrecans / Aggression / Agricultural_irrigation / Agriculture / Aids-related_complex / Air_pollution / Airway_management / Alanine / Alcohol_drinking / Alcoholics / Alcoholism / Alginates / Algorithms / Alkaloids / Alkynes / Alleles / Allergens / Allografts / Alloys / Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic_acid / Alpha-fetoproteins / Alphapapillomavirus / Altitude / Alzheimer_disease / Amaranth_dye / Ambulances / Amino_acid_substitution / Amino_acids / Aminoglycosides / Amlodipine / Amnion / Amoxicillin / Amplifiers,_electronic / Amputation,_surgical / Amputees / Amygdala / Amyloid / Amyotrophic_lateral_sclerosis / Analgesics / Anaphylaxis / Anastomotic_leak / Anatomy / Androgens / Anemia / Anemia,_iron-deficiency / Anesthesia / Anesthesiology / Anesthetics / Aneurysm,_false / Angina_pectoris / Angina,_unstable / Angiogenesis / Angiogenesis_inhibitors / Angiotensins / Anion_exchange_resins / Ankle / Anoikis / Anorexia_nervosa / Anterior_chamber / Anthocyanins / Anthracyclines / Anthropometry / Anti-inflammatory_agents,_non-steroidal / Antibodies,_bispecific / Antibodies,_monoclonal / Anticoagulants / Anticonvulsants / Antifibrinolytic_agents / Antihypertensive_agents / Antimicrobial_stewardship / Antineoplastic_agents / Antioxidants / Antiphospholipid_syndrome / Antipsychotic_agents / Antitubercular_agents / Antiviral_agents / Aorta / Aortic_aneurysm / Aortic_aneurysm,_abdominal / Aortic_dissection / Aortic_valve / Aphasia / Aphasia,_primary_progressive / Apicoplasts / Apolipoproteins / Apoptosis / Apoptosis_regulatory_proteins / Appendiceal_neoplasms / Appendicitis / Appendix / Appetite / Arboviruses / Arenavirus / Arginine / Arrhythmias,_cardiac / Arteriovenous_malformations / Arthralgia / Arthritis / Arthritis,_rheumatoid / Arthroplasty / Arthroplasty,_replacement,_knee / Artificial_intelligence / Artificially_sweetened_beverages / Ascorbic_acid / Aspartate_aminotransferases / Aspartic_acid / Aspergillosis / Aspergillosis,_allergic_bronchopulmonary / Asthenozoospermia / Astrocytes / Astrocytoma / Astronauts / Ataxia / Ataxia_telangiectasia / Atherectomy / Atherosclerosis / Athletes / Atrasentan / Atrial_fibrillation / Atrophy / Attention_deficit_disorder_with_hyperactivity / Attentional_bias / Attitude_to_health / Audiology / Augmented_reality / Authorship / Autism_spectrum_disorder / Autistic_disorder / Autoantibodies / Autoimmune_diseases / Autophagy / Autopsy / Axial_spondyloarthritis / Axons / B-lymphocytes / Back_pain / Bacterial_adhesion / Bacteriocins / Bacteriophages / Balantidiasis / Bariatric_surgery / Bartonella / Base_sequence / Basement_membrane / Basophils / Beds / Begomovirus / Behcet_syndrome / Benzene / Benzimidazoles / Benzocaine / Bevacizumab / Bezafibrate / Bibliometrics / Bicuspid / Bicuspid_aortic_valve_disease / Bilirubin / Biochemistry / Biocompatible_materials / Biodiversity / Biofilms / Biogenic_amines / Biological_availability / Biological_factors / Biological_monitoring / Biological_oxygen_demand_analysis / Biological_therapy / Biomarkers / Biomass / Biomedical_research / Biomimetics / Biophysics / Biopolymers / Biopsy / Biosimilar_pharmaceuticals / Biostatistics / Biotechnology / Birth_rate / Birth_weight / Blepharoplasty / Blindness / Blister / BLOOD / Blood_circulation / Blood_component_removal / Blood_culture / Blood_glucose / Blood_platelet_disorders / Blood_platelets / Blood_pressure / Blood_urea_nitrogen / Blood_vessels / Blood_volume / Blood-brain_barrier / Bocavirus / Body_composition / Body_mass_index / Body_size / Body_temperature / Body_weight / Bone_conduction / Bone_density / Bone_regeneration / Bone_transplantation / Botulinum_toxins / Brachytherapy / Brain_diseases / Brain_injuries / Brain_injuries,_traumatic / Brain_neoplasms / Bread / Breast_diseases / Breast_feeding / Breast_implants / Breast_neoplasms / Breeding / Bronchiectasis / Bronchiolitis_obliterans_syndrome / Bronchoalveolar_lavage / Bronchopulmonary_dysplasia / Bronchoscopy / Bruxism / Buffers / Burns / Butter / Calcinosis / Calcitonin / Calcium / Calcium_signaling / Camptothecin / Cancer_pain / Candy / Cannabidiol / Cannula / Capillaries / Capsaicin / Capsules / 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The Journal of Cachexia, Sarcopenia & Muscle ⟶

Apoptosis

The mitochondrial-targeted antioxidant SkQ1 prevents skeletal muscle mitochondrial-apoptotic but not necroptotic signalling during ovarian cancer.

Therapeutic Targeting of Decr1 Ameliorates Cardiomyopathy by Suppressing Mitochondrial Fatty Acid Oxidation in Diabetic Mice.

Melatonin Ameliorates Age-Related Sarcopenia via the Gut-Muscle Axis Mediated by Serum Lipopolysaccharide and Metabolites.

Electrospun microfibers to enhance nutrient supply in bioinks and 3D-bioprinted tissue precursors.

A fluorescent aptasensor for deoxynivalenol detection based on Nb.BbvCI-assisted targeted-responsive three-way junctions integrated DNA walking machine.

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