BACKGROUND
Sarcopenia, an age-related loss of skeletal muscle strength, mass and function, is linked with dementia and Alzheimer's disease (AD). Current guideline-recommended tools to diagnose sarcopenia, such as appendicular skeletal muscle mass (ASM), calculated as the sum of lean muscle mass...
BACKGROUND
Sarcopenia is an age-related process characterized by the loss of muscle mass and function, being a frailty component that affects the quality of life. It has been described as a risk factor for Alzheimer's disease dementia (ADD), and the coexistence...
BACKGROUND
Sarcopenia is associated with an increased risk of cognitive impairment, yet very few studies have examined structural brain changes in sarcopenia. The current study aims to explore cognitive changes and their neuroimaging correlates of individuals with sarcopenia in an urban...
As life expectancy increases, cognitive impairments such as Alzheimer's disease (AD) create serious problems for older adults. Women regardless of ethnicity and age group, are disproportionately affected, accounting for two-thirds of AD cases, with post-menopausal women representing over 60% of...
Sarcopenia is a complex and multifactorial condition, and recent studies have explored the role of neurological markers in its diagnosis and prediction. Although associations have been identified between reduced muscle strength, slow walking speed and elevated neurofilament levels (NfL), long-term...
Sarcopenia, with its complex diagnostic process, is a likely independent predictor of poor prognosis in patients with Alzheimer's disease (AD). However, research on the clinical characteristics and biomarkers of AD patients with sarcopenia (ADSA) is limited. This study included 180...
3D-bioprinting is a promising technique to mimic the complex anatomy of natural tissues, as it comprises a precise and gentle way of placing bioinks containing cells and hydrogel. Although hydrogels expose an ideal growth environment due to their extracellular matrix...
Deoxynivalenol (DON) contamination in cereals is a widespread issue with global implications, necessitating the development of efficient detection methods. Here, a fluorescent aptasensor integrating target-responsive DNA three-way junction (TWJ) and DNA walking machine was developed to detect DON. The DON-specific...
Both Alzheimer's disease (AD) and cerebral small vessel disease (CSVD) manifest in cognitive impairment and gait disorders. The precise similarities and differences in gait characteristics and underlying neuroimaging mechanisms remain unclear. A total of 399 participants were enrolled: 132 with...
