Proteome

Cachexia

Association Analysis of the Circulating Proteome With Sarcopenia-Related Traits Reveals Potential Drug Targets for Sarcopenia.

Sarcopenia severely affects the physical health of the elderly. Currently, there is no specific drug available for sarcopenia. This study aims to identify pathogenic proteins and druggable targets for sarcopenia through Mendelian randomization (MR)-based analytical framework. A sequential stepwise screening...

🗓️ 2025-02-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Biomarkers / Pharmaceutical_preparations / Proteome / Quantitative_trait_loci / Sarcopenia

Exercise

Electrospun microfibers to enhance nutrient supply in bioinks and 3D-bioprinted tissue precursors.

3D-bioprinting is a promising technique to mimic the complex anatomy of natural tissues, as it comprises a precise and gentle way of placing bioinks containing cells and hydrogel. Although hydrogels expose an ideal growth environment due to their extracellular matrix...

🗓️ 2024-12-11

📰 Publication: Biofabrication

2,2'-dipyridyl / 3-iodobenzylguanidine / 3,3'-diaminobenzidine / 3'_untranslated_regions / 5-methylcytosine / 5'_untranslated_regions / Abattoirs / Abdominal_muscles / Abdominal_neoplasms / Abdominal_pain / Abdominoplasty / Abortion,_spontaneous / Absenteeism / Absorption / Academic_medical_centers / Academic_performance / Accidental_falls / Accidents / Accounting / Acepromazine / Acetaldehyde / Acetals / Acetates / Acetylcholine / Acetylcholinesterase / Acetylcysteine / Acetylene / Acetylglucosamine / Acetyltransferases / Achievement / Acid_ceramidase / Acid_sensing_ion_channels / Acid-base_equilibrium / Acidosis / Acinetobacter / Acinetobacter_baumannii / Acne_vulgaris / Acoustics / Acquired_immunodeficiency_syndrome / Acromegaly / Acrylamide / Actins / Action_potentials / Activities_of_daily_living / Acute_care_surgery / Acute_coronary_syndrome / Acute_kidney_injury / Acute_lung_injury / Acyltransferases / Adaptation,_physiological / Adenocarcinoma_of_lung / Adenoma / Adenoma,_pleomorphic / Adenomyosis / Adenosine / Adhesives / Adipocytes / Adipocytes,_brown / Adipocytes,_white / Adipogenesis / Adiponectin / Adipose_tissue / Adiposity / Administration,_intranasal / Administration,_oral / Adolescent / Adrenal_cortex_hormones / Adrenocorticotropic_hormone / Adult_stem_cells / Advance_care_planning / Adverse_childhood_experiences / Advertising / Aeromonas_veronii / Aerosols / Aflatoxin_m1 / Aflatoxins / African_swine_fever / Aftercare / Agar / Agaricales / Age_distribution / Aged / Agent_orange / Aggregatibacter / Aggregatibacter_aphrophilus / Aggression / Aging,_premature / Agranulocytosis / Agricultural_irrigation / Agriculture / Agrochemicals / Aids-related_complex / Air_pollution / Alanine / Alcohol_drinking / Alcoholics / Aldehydes / Aldosterone / Alendronate / Alginates / Algorithms / Alkaline_phosphatase / Alkalosis / Alkanesulfonates / Alkynes / Alleles / Allergens / Allografts / Allopurinol / Alloys / Alopecia / Alopecia_areata / 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Exercise

A fluorescent aptasensor for deoxynivalenol detection based on Nb.BbvCI-assisted targeted-responsive three-way junctions integrated DNA walking machine.

Deoxynivalenol (DON) contamination in cereals is a widespread issue with global implications, necessitating the development of efficient detection methods. Here, a fluorescent aptasensor integrating target-responsive DNA three-way junction (TWJ) and DNA walking machine was developed to detect DON. The DON-specific...

🗓️ 2024-12-06

📰 Publication: Food Chemistry

1-phosphatidylinositol_4-kinase / 2-acetylaminofluorene / 3'_untranslated_regions / 5-hydroxytryptophan / Abdominal_pain / Abdominoplasty / Abetalipoproteinemia / Absenteeism / Absorption / Academic_performance / Accidental_falls / Accounting / Acetone / Acetylcholine / Achondroplasia / Acid_phosphatase / Acidosis,_renal_tubular / Acinetobacter_baumannii / Acitretin / Aconitic_acid / Acoustics / Acquired_immunodeficiency_syndrome / Acrylonitrile / Acute_kidney_injury / Acute_lung_injury / Adenocarcinoma / Adenocarcinoma_of_lung / Adenocarcinoma,_mucinous / Adenoidectomy / Adenoids / Adenomyosis / Adenosine / Adhesives / Adipocytes / Adipokines / Adipose_tissue / Adolescent / Adoptive_transfer / Adrenal_cortex_hormones / Adrenalectomy / Adrenocorticotropic_hormone / Aftercare / Agaricales / Aged / Ageism / Aggrecans / Aggression / Agricultural_irrigation / Agriculture / Aids-related_complex / Air_pollution / Airway_management / Alanine / Alcohol_drinking / Alcoholics / Alcoholism / Alginates / Algorithms / Alkaloids / Alkynes / Alleles / Allergens / Allografts / Alloys / Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic_acid / Alpha-fetoproteins / Alphapapillomavirus / Altitude / Alzheimer_disease / Amaranth_dye / Ambulances / Amino_acid_substitution / Amino_acids / Aminoglycosides / Amlodipine / Amnion / Amoxicillin / Amplifiers,_electronic / Amputation,_surgical / Amputees / Amygdala / Amyloid / Amyotrophic_lateral_sclerosis / Analgesics / Anaphylaxis / Anastomotic_leak / Anatomy / Androgens / Anemia / Anemia,_iron-deficiency / Anesthesia / Anesthesiology / Anesthetics / Aneurysm,_false / Angina_pectoris / Angina,_unstable / Angiogenesis / Angiogenesis_inhibitors / Angiotensins / Anion_exchange_resins / Ankle / Anoikis / Anorexia_nervosa / Anterior_chamber / Anthocyanins / Anthracyclines / Anthropometry / Anti-inflammatory_agents,_non-steroidal / Antibodies,_bispecific / Antibodies,_monoclonal / Anticoagulants / Anticonvulsants / Antifibrinolytic_agents / Antihypertensive_agents / Antimicrobial_stewardship / Antineoplastic_agents / Antioxidants / Antiphospholipid_syndrome / Antipsychotic_agents / Antitubercular_agents / Antiviral_agents / Aorta / Aortic_aneurysm / Aortic_aneurysm,_abdominal / Aortic_dissection / Aortic_valve / Aphasia / Aphasia,_primary_progressive / Apicoplasts / Apolipoproteins / Apoptosis / Apoptosis_regulatory_proteins / Appendiceal_neoplasms / Appendicitis / Appendix / Appetite / Arboviruses / Arenavirus / Arginine / Arrhythmias,_cardiac / Arteriovenous_malformations / Arthralgia / Arthritis / Arthritis,_rheumatoid / Arthroplasty / Arthroplasty,_replacement,_knee / Artificial_intelligence / Artificially_sweetened_beverages / Ascorbic_acid / Aspartate_aminotransferases / Aspartic_acid / Aspergillosis / Aspergillosis,_allergic_bronchopulmonary / Asthenozoospermia / Astrocytes / Astrocytoma / Astronauts / Ataxia / Ataxia_telangiectasia / Atherectomy / Atherosclerosis / Athletes / Atrasentan / Atrial_fibrillation / Atrophy / Attention_deficit_disorder_with_hyperactivity / Attentional_bias / Attitude_to_health / Audiology / Augmented_reality / Authorship / Autism_spectrum_disorder / Autistic_disorder / Autoantibodies / Autoimmune_diseases / Autophagy / Autopsy / Axial_spondyloarthritis / Axons / B-lymphocytes / Back_pain / Bacterial_adhesion / Bacteriocins / Bacteriophages / Balantidiasis / Bariatric_surgery / Bartonella / Base_sequence / Basement_membrane / Basophils / Beds / Begomovirus / Behcet_syndrome / Benzene / Benzimidazoles / Benzocaine / Bevacizumab / Bezafibrate / Bibliometrics / Bicuspid / Bicuspid_aortic_valve_disease / Bilirubin / Biochemistry / Biocompatible_materials / Biodiversity / Biofilms / Biogenic_amines / Biological_availability / Biological_factors / Biological_monitoring / Biological_oxygen_demand_analysis / Biological_therapy / Biomarkers / Biomass / Biomedical_research / Biomimetics / Biophysics / Biopolymers / Biopsy / Biosimilar_pharmaceuticals / Biostatistics / Biotechnology / Birth_rate / Birth_weight / Blepharoplasty / Blindness / Blister / BLOOD / Blood_circulation / Blood_component_removal / Blood_culture / Blood_glucose / Blood_platelet_disorders / Blood_platelets / Blood_pressure / Blood_urea_nitrogen / Blood_vessels / Blood_volume / Blood-brain_barrier / Bocavirus / Body_composition / Body_mass_index / Body_size / Body_temperature / Body_weight / Bone_conduction / Bone_density / Bone_regeneration / Bone_transplantation / Botulinum_toxins / Brachytherapy / Brain_diseases / Brain_injuries / Brain_injuries,_traumatic / Brain_neoplasms / Bread / Breast_diseases / Breast_feeding / Breast_implants / Breast_neoplasms / Breeding / Bronchiectasis / Bronchiolitis_obliterans_syndrome / Bronchoalveolar_lavage / Bronchopulmonary_dysplasia / Bronchoscopy / Bruxism / Buffers / Burns / Butter / Calcinosis / Calcitonin / Calcium / Calcium_signaling / Camptothecin / Cancer_pain / Candy / Cannabidiol / Cannula / Capillaries / Capsaicin / Capsules / Car-t_cell / Carbohydrates / Carbon_footprint / Carbonic_anhydrase_ix / Carbonic_anhydrases / Carboplatin / Carboxylic_acids / Carboxymethylcellulose_sodium / Carcinogenesis / Carcinoid_tumor / Carcinoma,_adenoid_cystic / Carcinoma,_hepatocellular / Carcinoma,_large_cell / Carcinoma,_lewis_lung / Carcinoma,_neuroendocrine / Carcinoma,_non-small-cell_lung / Carcinoma,_renal_cell / Carcinoma,_squamous_cell / Cardenolides / Cardia / Cardiac_catheterization / Cardiac_output / Cardiac_rehabilitation / Cardiology / Cardiomyopathies / Cardiomyopathy,_hypertrophic / Cardiopulmonary_bypass / Cardiopulmonary_resuscitation / Cardiotoxicity / Cardiovascular_diseases / Caregivers / Carotid_arteries / Carotid_artery,_common / Cartilage / Case-control_studies / Cataract / Catastrophization / Catenins / Cathepsins / Catheter_ablation / Catheters / Causality / Caves / Cd4_lymphocyte_count / Cefazolin / Cefoperazone / Ceftriaxone / Celiac_disease / Cell_adhesion / Cell_adhesion_molecules / Cell_biology / Cell_count / Cell_culture_techniques / Cell_cycle / Cell_death / Cell_line / Cell_membrane / Cell_proliferation / Cell_survival / Cell_transplantation / Cell-free_nucleic_acids / CELLS / Cellulite / Cellulose / Central_amygdaloid_nucleus / Central_nervous_system / Central_nervous_system_stimulants / Ceramics / Cerclage,_cervical / Cerebellum / Cerebral_amyloid_angiopathy / Cerebral_palsy / Cerebrovascular_disorders / Cesarean_section / Chalcone / Chalcones / Chemistry,_pharmaceutical / Chemoprevention / Chemoradiotherapy / Chemotherapy,_adjuvant / Chickenpox / Child_abuse / Child_health / Child,_hospitalized / Child,_preschool / Chitinases / Chitosan / Chlorophyll / Chloroplasts / Choice_behavior / Cholangiocarcinoma / Cholangiography / Cholecystectomy / Cholera / Cholesteatoma / Cholesterol / Cholesterol,_hdl / Cholesterol,_ldl / Cholinergic_agents / Chondrocytes / Choroid / Choroid_plexus / Chromatin / Chromatin_immunoprecipitation_sequencing / Chromogranins / Chromosomes / 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Monophenol_monooxygenase / Morphine / Morris_water_maze_test / MORTALITY / Mosaic_viruses / Mothers / Motivation / Motivational_interviewing / Motor_activity / Mouth / Mouth_neoplasms / Movement / Moxibustion / Mucosa-associated_lymphoid_tissue_lymphoma_translocation_1_protein / Mucous_membrane / Multimodal_imaging / Multiparametric_magnetic_resonance_imaging / Multiple_chronic_conditions / Multiple_myeloma / Multiple_sclerosis / Multiple_sclerosis,_relapsing-remitting / Multivariate_analysis / Muscle_cells / Muscle_spasticity / Muscle_strength / Muscle,_skeletal / Muscle,_smooth / muscles / Muscular_dystrophies / Muscular_dystrophy,_duchenne / Musculoskeletal_diseases / Musculoskeletal_system / Mutagenesis / Mutation / Mutation,_missense / Myalgia / Mycobacterium / Mycoses / Myeloid_cells / Myeloid-derived_suppressor_cells / Myoblasts / Myoblasts,_skeletal / Myocardial_infarction / Myocardium / Myocytes,_cardiac / Myocytes,_smooth_muscle / Myofibroblasts / Myokymia / Myoma / Myopia / 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/ PREGNANCY / Pregnancy_outcome / Pregnancy_rate / Pregnancy_trimester,_second / Pregnancy_trimester,_third / Pregnancy,_ectopic / Pregnancy,_interstitial / Pregnancy,_multiple / Pregnancy,_twin / Pregnant_women / Premature_birth / Prenatal_care / Prescription_drugs / PREVALENCE / Preventive_health_services / Preventive_medicine / Primary_myelofibrosis / Primary_ovarian_insufficiency / Prion_diseases / Prions / Prisons / Privacy / Probability / Probiotics / Procollagen / Professional_role / Progesterone / Prognosis / Programmed_cell_death_1_receptor / Progression-free_survival / Prolactin / Promoter_regions,_genetic / Propensity_score / Prophages / Propidium / Propofol / Proportional_hazards_models / Prospective_studies / Prostaglandin-endoperoxide_synthases / Prostate / Prostatectomy / Prostatic_neoplasms / Prostheses_and_implants / Prosthesis_design / Prosthesis_fitting / Prosthodontics / Protective_factors / Protein_biosynthesis / Protein_engineering / Protein_isoforms / 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Cachexia

Skeletal Muscle Proteome Modifications following Antibiotic-Induced Microbial Disturbances in Cancer Cachexia.

Cancer cachexia is an involuntary loss of body weight, mostly of skeletal muscle. Previous research favors the existence of a microbiota-muscle crosstalk, so the aim of the study was to evaluate the impact of microbiota alterations induced by antibiotics on...

🗓️ 2024-06-19

📰 Publication: Journal Of Proteome Research

Cancer-associatedcachexia / Microbiota / Muscle,Skeletal / Muscleproteins / muscles / neoplasms / Proteome / Proteomics

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The Journal of Cachexia, Sarcopenia & Muscle ⟶

Proteome

Association Analysis of the Circulating Proteome With Sarcopenia-Related Traits Reveals Potential Drug Targets for Sarcopenia.

Electrospun microfibers to enhance nutrient supply in bioinks and 3D-bioprinted tissue precursors.

A fluorescent aptasensor for deoxynivalenol detection based on Nb.BbvCI-assisted targeted-responsive three-way junctions integrated DNA walking machine.

Skeletal Muscle Proteome Modifications following Antibiotic-Induced Microbial Disturbances in Cancer Cachexia.

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