BLOOD

Muscle

Blood-Brain Barrier-Penetrating Nanocarriers Enable Microglial-Specific Drug Delivery in Hypothalamic Neuroinflammation.

Hypothalamic inflammation plays a pivotal role in appetite dysregulation across various pathological conditions, including cancer cachexia. However, delivering anti-inflammatory agents to microglia, key mediators of hypothalamic inflammation, remains challenging due to the unsurmountable blood-brain barrier (BBB). To overcome this challenge,...

🗓️ 2025-04-03

📰 Publication: Advanced Healthcare Materials

BLOOD / Blood-brain_barrier / cachexia / Cancer-associated_cachexia / Microglia / muscles / neoplasms / Pharmaceutical_preparations / therapeutics

Muscle

Detrimental Effects of β2-Microglobulin on Muscle Metabolism: Evidence From In Vitro, Animal and Human Research.

β2-Microglobulin (B2M) has garnered considerable interest as a potential pro-ageing factor, leading to speculation about its involvement in muscle metabolism and the development of sarcopenia, a key component of ageing phenotypes. To explore this hypothesis, we conducted a comprehensive investigation...

🗓️ 2025-04-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Biomarkers / BLOOD / cachexia / Gait / Hand_strength / muscles / Phenotype / Research / Sarcopenia / SERUM / Walking_speed

Exercise

Device-Measured Physical Activity, Sedentary Behaviour and Risk of Chronic Kidney Diseases Across Levels of Grip Strength.

The study aimed to investigate whether the associations of accelerometer-measured physical activity (PA) and sedentary behaviour (SB) with incident chronic kidney disease (CKD) vary based on different levels of hand grip strength, identifying the modifying role of grip strength in...

🗓️ 2025-02-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

BLOOD / Hand_strength / Incidence / Kidney / Kidney_diseases / Renal_insufficiency,_chronic / Sarcopenia / Sedentary_behavior

Muscle

The Effect of Anti-Activin Receptor Type IIA and Type IIB Antibody on Muscle, Bone and Blood in Healthy and Osteosarcopenic Mice.

Anti-Activin Receptor Type IIA and Type IIB antibody (αActRIIA/IIB ab) is a recently developed drug class that targets the activin receptor signalling pathway. Inhibition of receptor ligands (activins, myostatin, growth differentiation factor 11, etc.) can lead to skeletal muscle hypertrophy,...

🗓️ 2025-02-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Activin_receptors / Activins / BLOOD / Blood_cells / cachexia / Cancellous_bone / CELLS / Cortical_bone / Erythrocytes / Hematopoiesis / Injections / Ligands / Muscle,_skeletal / muscles / Osteoporosis / Paresis / Sarcopenia / therapeutics

Exercise

Electrospun microfibers to enhance nutrient supply in bioinks and 3D-bioprinted tissue precursors.

3D-bioprinting is a promising technique to mimic the complex anatomy of natural tissues, as it comprises a precise and gentle way of placing bioinks containing cells and hydrogel. Although hydrogels expose an ideal growth environment due to their extracellular matrix...

🗓️ 2024-12-11

📰 Publication: Biofabrication

2,2'-dipyridyl / 3-iodobenzylguanidine / 3,3'-diaminobenzidine / 3'_untranslated_regions / 5-methylcytosine / 5'_untranslated_regions / Abattoirs / Abdominal_muscles / Abdominal_neoplasms / Abdominal_pain / Abdominoplasty / Abortion,_spontaneous / Absenteeism / Absorption / Academic_medical_centers / Academic_performance / Accidental_falls / Accidents / Accounting / Acepromazine / Acetaldehyde / Acetals / Acetates / Acetylcholine / Acetylcholinesterase / Acetylcysteine / Acetylene / Acetylglucosamine / Acetyltransferases / Achievement / Acid_ceramidase / Acid_sensing_ion_channels / Acid-base_equilibrium / Acidosis / Acinetobacter / Acinetobacter_baumannii / Acne_vulgaris / Acoustics / Acquired_immunodeficiency_syndrome / Acromegaly / Acrylamide / Actins / Action_potentials / Activities_of_daily_living / Acute_care_surgery / Acute_coronary_syndrome / Acute_kidney_injury / Acute_lung_injury / Acyltransferases / Adaptation,_physiological / Adenocarcinoma_of_lung / Adenoma / Adenoma,_pleomorphic / Adenomyosis / Adenosine / Adhesives / Adipocytes / Adipocytes,_brown / Adipocytes,_white / Adipogenesis / Adiponectin / Adipose_tissue / Adiposity / Administration,_intranasal / Administration,_oral / Adolescent / Adrenal_cortex_hormones / Adrenocorticotropic_hormone / Adult_stem_cells / Advance_care_planning / Adverse_childhood_experiences / Advertising / Aeromonas_veronii / Aerosols / Aflatoxin_m1 / Aflatoxins / African_swine_fever / Aftercare / Agar / Agaricales / Age_distribution / Aged / Agent_orange / Aggregatibacter / Aggregatibacter_aphrophilus / Aggression / Aging,_premature / Agranulocytosis / Agricultural_irrigation / Agriculture / Agrochemicals / Aids-related_complex / Air_pollution / Alanine / Alcohol_drinking / Alcoholics / Aldehydes / Aldosterone / Alendronate / Alginates / Algorithms / Alkaline_phosphatase / Alkalosis / Alkanesulfonates / Alkynes / Alleles / Allergens / Allografts / Allopurinol / Alloys / Alopecia / Alopecia_areata / Alpha_1-antitrypsin / Alpha_1-antitrypsin_deficiency / Alpha-glucosidases / Alpha-linolenic_acid / Alpha-synuclein / Alphapapillomavirus / Altitude / Alzheimer_disease / Amanita / Ambulances / Ambulatory_care / Ambulatory_care_facilities / Amikacin / Amine_oxidase_(copper-containing) / Amines / Amino_acid_sequence / Amino_acid_substitution / Amino_acids / Amino_acids,_branched-chain / Amino_acids,_sulfur / Amino_alcohols / Aminolevulinic_acid / Amlodipine / Amoxicillin / Amphetamines / Amphotericin_b / Amplifiers,_electronic / Amputation,_surgical / Amputees / Amygdala / Amyloid / Amyloidosis / Amylopectin / Amyotrophic_lateral_sclerosis / Analgesia / Analgesics / Analysis_of_variance / Anaphylaxis / Anastomotic_leak / Anemia / Anemia,_aplastic / Anemia,_iron-deficiency / Anemia,_sickle_cell / Anesthesia / Anesthesia,_conduction / Anesthesia,_epidural / Anesthesia,_intravenous / Anesthesia,_local / Anesthesia,_obstetrical / Anesthesiologists / Anesthesiology / Anesthetics / Anesthetics,_local / Aneuploidy / Aneurysm,_false / Anger / Angina_pectoris / Angioedema / Angioedemas,_hereditary / Angiopoietins / Angiotensins / Anhydrides / Aniline_compounds / Animal_communication / Anisometropia / Ankle / Ankyloglossia / Ankylosis / Annexin_a5 / Annexins / Anoikis / Anosmia / Anterior_chamber / Anterior_cruciate_ligament_injuries / Anthelmintics / Anthocyanins / Anthracyclines / Anthropology / Anthropometry / Anti-bacterial_agents / Anti-inflammatory_agents,_non-steroidal / Antibiotic_prophylaxis / Antibodies / Antibodies,_antineutrophil_cytoplasmic / Antibodies,_blocking / Antibodies,_monoclonal / Antibodies,_neutralizing / Antibody_formation / Anticoagulants / Antidepressive_agents / Antigen-presenting_cells / Antigens,_nuclear / Antigens,_surface / Antihypertensive_agents / Antimicrobial_stewardship / Antineoplastic_agents / Antioxidants / Antiphospholipid_syndrome / Antipsychotic_agents / Antipyretics / Antiviral_agents / Anxiety_disorders / Aorta / Aortic_aneurysm / Aortic_aneurysm,_abdominal / Aortic_aneurysm,_thoracic / Aortic_aneurysm,_thoracoabdominal / Aortic_diseases / Aortic_dissection / Aortic_rupture / Aortic_valve / Aortic_valve_disease / Apathy / Apelin / Aphasia / Apigenin / Apolipoproteins / Apoprotein(a) / Apoptosis / Appendectomy / Appendicitis / Appendix / Appetite / Aquaculture / Aquatic_organisms / Arachnoiditis / Archaea / Archives / Area_under_curve / Arginine / Argon_plasma_coagulation / Aristolochic_acids / Arrestin / Arrhythmias,_cardiac / Arterial_occlusive_diseases / Arterioles / Arteriovenous_fistula / Arteriovenous_malformations / Arterivirus / Arthritis,_psoriatic / Arthritis,_reactive / Arthritis,_rheumatoid / Arthrodermataceae / Arthroplasty,_replacement,_knee / Arthroscopy / Artificial_intelligence / Artificial_limbs / Ascorbic_acid / Aspartate_aminotransferases / Aspartic_acid / Aspergillus / Aspergillus_niger / Aspirin / Asthma / Astigmatism / Astringents / Astrocytes / Astrocytoma / Ataxia / Atenolol / Atherosclerosis / Athletes / Athletic_performance / Atmosphere / Atorvastatin / Atrial_appendage / Atrial_fibrillation / Atrial_flutter / Atrophy / Attention_deficit_disorder_with_hyperactivity / Attentional_bias / Audiometry / Audiovisual_aids / Augmented_reality / Autism_spectrum_disorder / Autistic_disorder / Autoantigens / Autoimmune_diseases / Autoimmunity / Automation / Autophagosomes / Autophagy / Autopsy / Axenic_culture / Axial_spondyloarthritis / Axillary_vein / Axons / Azacitidine / Azathioprine / Azoospermia / Azospirillum / Azospirillum_brasilense / B-lymphocytes / Bacillus / Bacillus_amyloliquefaciens / Bacillus_subtilis / Back_pain / Bacterial_adhesion / Bacterial_infections / Bacterial_load / Bacteriocins / Bacteriophages / Bacteroides / Bacteroides_fragilis / Badnavirus / Bariatric_surgery / Bartonella / Bartonella_quintana / Basal_ganglia / Basal_nucleus_of_meynert / Basement_membrane / Basidiomycota / Basolateral_nuclear_complex / Beauty / Beckwith-wiedemann_syndrome / Beds / Begomovirus / Behavior_therapy / Behavior,_animal / Behavioral_symptoms / Benchmarking / Benserazide / Benzene / Benzocaine / Benzodiazepines / Benzyl_alcohol / Berberine / Beta-lactams / Betaine / Betaine-homocysteine_s-methyltransferase / Bevacizumab / Beverages / Bezafibrate / Bezoars / Bias / Bibliometrics / Bicuspid / Bicuspid_aortic_valve_disease / Bifidobacterium / Bifidobacterium_longum / Bile / Bile_ducts / Biliary_tract / Bilirubin / Binge-eating_disorder / Biocompatible_materials / Biodegradable_plastics / Biodegradation,_environmental / Biodiversity / Biofeedback,_psychology / Biofilms / Biological_assay / Biological_availability / Biological_science_disciplines / Biological_therapy / Biomarkers / Biomarkers,_tumor / Biomass / Biomedical_research / Biometry / Biomimetics / Bioprinting / Biosimilar_pharmaceuticals / Biosurveillance / Biotransformation / Bipolar_disorder / Birth_certificates / Birth_order / Birth_weight / Bleomycin / Blindness / BLOOD / Blood_cell_count / Blood_cells / Blood_circulation / Blood_coagulation_factors / Blood_component_removal / Blood_culture / Blood_donors / Blood_glucose / Blood_platelets / Blood_pressure / Blood_pressure_monitoring,_ambulatory / Blood_substitutes / Blood_transfusion,_intrauterine / Blood_urea_nitrogen / Blood_vessels / Blood_volume / Blotting,_western / Body_composition / Body_contouring / Body_image / Body_mass_index / Body_size / Body_weight / Bone_cements / Bone_cysts / Bone_diseases / Bone_marrow / Bone_neoplasms / Bone_regeneration / Bone_transplantation / Bony_callus / Borates / Botany / Botulinum_toxins / Botulinum_toxins,_type_a / Botulism / Bowen's_disease / Bradycardia / Bradykinin / Brain / Brain_diseases / Brain_injuries / Brain_injuries,_traumatic / Brain_ischemia / Brain_stem / Brain_stem_infarctions / Bread / Breast / Breast_cancer_lymphedema / Breast_feeding / Breast_neoplasms / Bronchiectasis / Bronchiolitis_obliterans_syndrome / Bronchitis / Bronchogenic_cyst / Bronchopulmonary_sequestration / Bronchoscopy / Brucella / Brucellosis / Brugada_syndrome / Budesonide / Buffers / Bulimia / Bundle-branch_block / Bupropion / Burning_mouth_syndrome / Burnout,_psychological / Burns / Butter / Butyrylcholinesterase / C-peptide / C-reactive_protein / Ca-19-9_antigen / cachexia / Caco-2_cells / Cadherins / Caffeine / Calcitonin_gene-related_peptide / Calcium / Calcium_channel_blockers / Calcium_channels / Calcium_signaling / Cancer_vaccines / Cancer-associated_cachexia / Cancer-associated_fibroblasts / Candidemia / Candidiasis / Candidiasis,_invasive / Candidiasis,_vulvovaginal / Cannabidiol / Cannula / Capacity_building / Capillaries / Capsaicin / Capsid / Capsules / Car-t_cell / Carbamazepine / Carbapenems / Carbidopa / Carbohydrates / Carboxylic_acids / Carcinogenesis / Carcinogens / Carcinoid_tumor / Carcinoma_in_situ / Carcinoma,_basal_cell / Carcinoma,_hepatocellular / Carcinoma,_intraductal,_noninfiltrating / Carcinoma,_non-small-cell_lung / Carcinoma,_ovarian_epithelial / Carcinoma,_renal_cell / Carcinoma,_squamous_cell / Cardiac_catheters / Cardiac_output / Cardiac_rehabilitation / Cardiac_resynchronization_therapy / Cardiac_volume / Cardiology / Cardiomyopathy,_restrictive / Cardiopulmonary_bypass / Cardiopulmonary_resuscitation / Cardiotoxicity / Cardiovascular_diseases / Cardiovascular_system / Caregivers / Carotenoids / Carotid_arteries / Carotid_artery,_internal / Carrier_proteins / Case-control_studies / Caseins / Caspase_3 / Caspase_9 / Caspases / Castleman_disease / Castration / Catalase / Cataract / Catastrophization / Catechin / Catechol_o-methyltransferase / Catecholamines / Catenins / Catheter_ablation / Catheterization / Causality / Caveolins / Cecum / Cefazolin / Cefoperazone / Cefotaxime / Ceftazidime / Ceftriaxone / Celiac_disease / Cell_aggregation / Cell_biology / Cell_body / Cell_communication / Cell_count / Cell_culture_techniques / Cell_cycle / Cell_death / Cell_differentiation / Cell_fusion / Cell_line / Cell_membrane / Cell_proliferation / Cell_survival / Cell_transplantation / Cell_wall / Cell-free_nucleic_acids / CELLS / Cellular_senescence / Cellulose / Censuses / Centers_for_disease_control_and_prevention,_u.s. / Central_amygdaloid_nucleus / Central_nervous_system / Central_nervous_system_diseases / Central_nervous_system_sensitization / Central_venous_catheters / Centromere / Cephalosporins / Ceramics / Ceramidases / Ceramides / Cerebellar_ataxia / Cerebellum / Cerebral_arteries / Cerebral_cortex / Cerebral_hemorrhage / Cerebral_infarction / Cerebral_palsy / Cerebral_small_vessel_diseases / Cerebrospinal_fluid_leak / Cerebrospinal_fluid_rhinorrhea / Cerebrovascular_circulation / Cerebrovascular_disorders / Cervical_cord / Cervical_vertebrae / Cervix_uteri / Cesarean_section / Chagas_disease / Chaperonins / Charcot-marie-tooth_disease / Cheese / Chemical_safety / Chemistry,_clinical / Chemokine_ccl11 / Chemokine_ccl22 / Chemokine_cx3cl1 / Chemokine_cxcl12 / Chemokines / Chemokines,_cxc / Chemoprevention / Chemoradiotherapy / Chemotherapy,_adjuvant / Chest_pain / Chick_embryo / Chickenpox / Chikungunya_virus / Child_abuse,_sexual / Child_custody / Child_development / Child_health / Child_health_services / Child,_hospitalized / Child,_preschool / Chimera / Chimerism / Chitin / Chitosan / Chlamydia / Chloramphenicol / Chlorogenic_acid / Chlorophyll / Chlorophyll_a / Chloroplasts / Chlortetracycline / Cholangiocarcinoma / Cholangiography / Cholangitis / Cholecalciferol / Cholecystectomy / Cholecystitis / Cholecystitis,_acute / Choledocholithiasis / Cholera / Cholestasis / Cholestasis,_intrahepatic / Cholesterol / Cholesterol_esters / Cholesterol,_hdl / Cholesterol,_ldl / Cholinergic_agents / Chondrocytes / Chondrogenesis / Chondroitin / Chondroitin_sulfates / Chordoma / Chorea / Chorioamnionitis / Chromatin / Chromatin_immunoprecipitation / Chromogranin_a / Chromogranins / Chromosome_aberrations / Chronic_disease / Chronic_pain / Chylothorax / Chylous_ascites / Cicatrix / Cilia / Ciprofloxacin / Circadian_clocks / Circovirus / Circulating_microrna / Circulating_tumor_dna / Citalopram / Citizen_science / Citric_acid / Citrinin / Citrobacter / Citrobacter_rodentium / Citrulline / Cladribine / Classical_swine_fever / Clathrin / Clay / Climacteric / Climate / Clinical_alarms / Clinical_decision-making / Clinical_laboratory_techniques / Clitoris / Clobazam / Clone_cells / Clonidine / Clostridioides / Clostridioides_difficile / Clostridium / Cloud_computing / Clozapine / Cluster_analysis / Clustered_regularly_interspaced_short_palindromic_repeats / Clutch_size / Coagulase / Coal / Coal_industry / Coccidioidomycosis / Cochlear_implants / Cochlear_nucleus / Coconut_oil / Codon / Coffee / Cognition_disorders / Cognitive_behavioral_therapy / Cognitive_dissonance / Cognitive_dysfunction / Cognitive_restructuring / Cognitive_training / Cohort_studies / Coinfection / Colchicine / Cold_temperature / Colectomy / Colic / Colistin / Colitis / Colitis,_ulcerative / Collagen / Collagen_type_i / Collagen_type_ii / Collagenases / Collectins / Colletotrichum / Collodion / COLON / Colon,_ascending / Colon,_sigmoid / Colon,_transverse / Colonic_neoplasms / Colonoscopy / Colony-stimulating_factors / Colorectal_neoplasms / Colorectal_surgery / Colostomy / Colposcopy / Coma,_post-head_injury / Commerce / Common_variable_immunodeficiency / Communicable_diseases / Communicable_diseases,_emerging / Communication / Community_health_workers / Community_participation / Comorbidity / Compartment_syndromes / Complement_activation / Complement_c1_inhibitor_protein / Complement_c1q / Complement_c3a / Complement_inactivating_agents / Complement_system_proteins / Complementary_therapies / Complex_regional_pain_syndromes / Composite_resins / Composting / Computational_chemistry / Computed_tomography_angiography / Computers / Conditioning,_psychological / Confidence_intervals / Confined_spaces / Conflict_of_interest / Conflict,_psychological / Congo_red / Connective_tissue / Consciousness / Consent_forms / Conservative_treatment / Constipation / Contact_lenses / Continuous_glucose_monitoring / Contraceptive_agents / Contracture / Contraindications / Contusions / Conversion_disorder / Conversion_to_open_surgery / Cooperative_behavior / Coral_reefs / Cornea / Coronary_artery_bypass / Coronary_artery_disease / Coronary_disease / Coronary_sinus / Coronavirus_infections / Cost_of_illness / Cost_savings / Coumarins / Covid-19 / Covid-19_testing / Cranial_nerves / Craniopharyngioma / Craniotomy / Craving / Creatine / Creativity / Creutzfeldt-jakob_syndrome / Criminal_law / Critical_care / Critical_illness / Critical_period,_psychological / Crohn_disease / Cronobacter / Cronobacter_sakazakii / Crop_production / Cross_infection / Cross-over_studies / Cross-sectional_studies / Crowdsourcing / Crowns / Cryogels / Cryoglobulinemia / Cryoglobulins / Cryopreservation / Cryosurgery / Cryotherapy / Cryptochromes / Cryptorchidism / Cubital_tunnel_syndrome / Culture_media,_conditioned / Curcumin / Curriculum / Cushing_syndrome / Cyanobacteria / Cycloaddition_reaction / Cyclodextrins / Cyclophosphamide / Cyclosporine / Cystadenocarcinoma / Cystadenocarcinoma,_serous / Cystatins / Cysteine / Cysteine_proteases / Cystine / Cysts / Cytochrome_p-450_enzyme_system / Cytochromes / Cytogenetics / Cytokinins / Cytology / Cytoplasm / Cytoskeleton / Dairy_products / Data_analysis / Data_collection / Data_management / Data_mining / Data_science / Data_warehousing / Databases,_protein / Deafness / Death,_sudden,_cardiac / Debridement / Decision_making / Decision_making,_shared / Decision_support_systems,_clinical / Decompression / Decontamination / Deep_brain_stimulation / Deep_learning / Default_mode_network / Defibrillators / Defibrillators,_implantable / Deglutition / Deglutition_disorders / Dehydration / Delayed_diagnosis / Delirium / Dementia / Demography / Dendrites / Dendritic_cells / Dengue / Dengue_virus / Denosumab / Dental_cements / Dental_debonding / Dental_enamel / Dental_implants / Dental_materials / Dental_prosthesis / Dental_pulp_capping / Dental_pulp_necrosis / Dentate_gyrus / Dentin / Dentistry / Dentists / Dentition / Dentition,_mixed / Dentures / Deoxyuridine / Dependency,_psychological / Depression / Depression,_postpartum / Depressive_disorder / Depressive_disorder,_major / Dermatitis / Dermatitis,_atopic / Dermatology / Dermis / Detergents / Developing_countries / Developmental_biology / Developmental_disabilities / Dexmedetomidine / Dextrocardia / Diabetes_mellitus / Diabetes_mellitus,_type_1 / Diabetes_mellitus,_type_2 / Diabetes,_gestational / Diabetic_cardiomyopathies / Diabetic_foot / Diabetic_nephropathies / Diabetic_neuropathies / Diabetic_retinopathy / Diagnosis-related_groups / Diagnostic_imaging / Diamines / Diapause / Diaphragm / Diarrhea / Diazomethane / Diestrus / Diet / Diet_records / Diet,_gluten-free / Diet,_healthy / Diet,_ketogenic / Diet,_mediterranean / Diet,_vegan / Diet,_vegetarian / Dietary_exposure / Dietary_fats / Dietary_fiber / Dietary_patterns / Dietary_supplements / Diethylhexyl_phthalate / Diffusion_tensor_imaging / Digeorge_syndrome / Digestion / Digital_health / Digital_technology / Digital_therapeutics / Diglycerides / Dioxins / Dipeptidyl_peptidase_4 / Dipeptidyl-peptidase_iv_inhibitors / Diphosphonates / Disabled_children / Disabled_persons / Disaster_medicine / Discriminant_analysis / Disease_management / Disease_progression / Disease_transmission,_infectious / Disease-free_survival / Disinfectants / Diskectomy / Displacement,_psychological / Dissection,_thoracic_aorta / Disseminated_intravascular_coagulation / Distemper_virus,_canine / Disulfides / Disulfiram / Diuretics / Diverticular_diseases / Diverticulitis / Diverticulum / Diving / Dizziness / Dna_damage / Dna_glycosylases / Dna_gyrase / Dna_methylation / Dna_nucleotidylexotransferase / Dna_replication / Dna_topoisomerase_iv / Dna_transposable_elements / Dna,_catalytic / Dna,_mitochondrial / Dna,_single-stranded / Dobutamine / Documentation / Dom_2,5-dimethoxy-4-methylamphetamine / Donor_selection / Dopamine / Dopamine_plasma_membrane_transport_proteins / Dorsal_raphe_nucleus / Down_syndrome / Down-regulation / Doxorubicin / Dravet_syndrome / Drinking_water / Drought_resistance / Droughts / Drowning / Drug_candidate / Drug_carriers / Drug_combinations / Drug_delivery_systems / Drug_discovery / Drug_evaluation / Drug_evaluation,_preclinical / Drug_interactions / Drug_liberation / Drug_monitoring / Drug_resistance / Drug_resistance,_multiple / Drug_therapy / Drug_tolerance / Drug_users / Drug-related_side_effects_and_adverse_reactions / Dry_eye_syndromes / Duodenal_ulcer / Duodenum / Duration_of_therapy / Dysentery,_amebic / Dysmenorrhea / Dyspepsia / Dyspnea / Dystocia / Dystroglycans / Dystrophin / Ear_cartilage / Ear_diseases / Ear,_inner / Ear,_middle / Early_diagnosis / Earthquakes / Eating / Ebstein_anomaly / Echocardiography / Ecological_momentary_assessment / Ecology / Economics / Economics,_behavioral / Ecosystem / Ectopia_lentis / Ectropion / Eczema / Edaravone / Edible_grain / Education,_medical / Education,_medical,_continuing / Education,_medical,_undergraduate / Egg_yolk / Eggs / Eicosapentaenoic_acid / Ejaculation / Elasticity_imaging_techniques / Elastomers / Electric_power_supplies / Electroacupuncture / Electrocardiography / Electroconvulsive_therapy / Electrodes / Electroencephalography / Electronic_health_records / Electronic_medical_record / Electronic_nicotine_delivery_systems / Electrophysiology / Electroporation / Embolism,_fat / Embryo_transfer / Embryonic_development / Emergencies / Emergency_medical_services / Emergency_medicine / Emergency_responders / Emergency_service,_hospital / Emergency_shelter / Emotional_regulation / Emotions / Employment / Empowerment / Emulsions / Endarterectomy / Endocannabinoids / Endocarditis / Endocytosis / Endodontics / Endoleak / Endometrial_neoplasms / Endometriosis / Endopeptidases / Endophthalmitis / Endophytes / Endoplasmic_reticulum / Endoplasmic_reticulum_stress / Endoscopes / Endoscopic_mucosal_resection / Endoscopy / Endoscopy,_gastrointestinal / Endothelial_cells / Endothelial_growth_factors / Endothelin_receptor_antagonists / Endothelin-1 / Endothelium / Endotoxins / Endurance_training / Enema / Energy_drinks / Energy_intake / Enhanced_recovery_after_surgery / Enhancer_elements,_genetic / Enteral_nutrition / Enterobacter / Enterococcus / Enterococcus_faecium / Enteropathogenic_escherichia_coli / Enterotoxigenic_escherichia_coli / Enterotoxins / Enterovirus / Environment_design / Environmental_health / Environmental_monitoring / Environmental_policy / Environmental_pollutants / Environmental_pollution / Enzyme-linked_immunosorbent_assay / Enzymes / Eosinophilia / Eosinophils / Ependymoma / Epidemics / Epidemiologic_studies / epidemiology / Epididymis / Epigenome / Epiglottis / Epilepsies,_partial / Epilepsy / Epilepsy,_absence / Epilepsy,_temporal_lobe / Episiotomy / Epithelial_cells / Epithelial-mesenchymal_transition / Epithelium,_corneal / Erythrocyte_transfusion / Erythrocytes / Erythropoietin / Escherichia_coli / Esophageal_fistula / Esophageal_neoplasms / Esophageal_sphincter,_lower / Esophageal_squamous_cell_carcinoma / Esophagectomy / Esophagogastric_junction / Esophagus / Estrus_detection / Ether / Ethics / Ethics,_medical / Ethmoid_sinus / Ethylene_glycol / Ethylene_oxide / Etomidate / European_union / Evolution,_molecular / Exanthema / Excitation_contraction_coupling / Executive_function / Exercise_test / Exercise_therapy / Exome / Exome_sequencing / Exons / Exosomes / Explosive_agents / External_fixators / Extracellular_matrix / Extracellular_vesicles / Extracorporeal_membrane_oxygenation / Extreme_weather / Eye / Eye_diseases / Eye_movements / Eyeglasses / Eyelids / Facial_expression / Facial_paralysis / Facial_recognition / Factor_viii / Factor_xi_deficiency / Failure_to_thrive / Fallopian_tubes / Famciclovir / Family_practice / Family_relations / Family_structure / Fanconi_syndrome / Farms / Fasciitis,_plantar / Fasting / Fathers / FATIGUE / Fatigue_syndrome,_chronic / Fatty_acid-binding_proteins / Fatty_acids / Fatty_acids,_omega-3 / Fatty_acids,_volatile / Fatty_liver / Fear / Feasibility_studies / Febuxostat / Fecal_incontinence / Feedback / Feedback,_sensory / Feeding_behavior / Femoracetabular_impingement / Femoral_fractures,_distal / Fentanyl / Ferritins / Ferroptosis / Fertility / Fertilization / Fertilization_in_vitro / Fertilizers / Fetal_hemoglobin / Fetuins / Fetus / Fibrin / Fibrinogen / Fibrinolysin / Fibroblast_growth_factors / Fibrocartilage / Fibroins / Fibronectins / Fibrosis / Fires / Fish_oils / Fistula / Flank_pain / Flavivirus / Flavonoids / Flowmeters / Flucytosine / Fluid_therapy / Fluorescent_dyes / Fluoroquinolones / Fluoroscopy / Fluorouracil / Focus_groups / Folliculitis / Follow-up_studies / Food_addiction / Food_additives / Food_analysis / Food_hypersensitivity / Food_ingredients / Food_insecurity / Food_packaging / Food_safety / Food_security / Food_supply / Food,_processed / Foot / Football / Forensic_dentistry / Forensic_genetics / Forensic_sciences / Forestry / Forests / Forgiveness / Foundations / Fracture_dislocation / Fractures,_bone / Fractures,_open / Fractures,_stress / Frailty / Free_tissue_flaps / Fresh_water / Frontal_sinus / Fruit / Functional_neuroimaging / Fundoplication / Fungi / G1_phase / Gabaergic_neurons / Gabapentin / Gadolinium_dtpa / Gait / Galactose / Galactosidases / Galectin_3 / Galectins / Gallbladder / Gallbladder_diseases / Gamma_rhythm / Gamma-aminobutyric_acid / Ganglion_cysts / Ganglioneuroma / Gangrene / Ganoderma / Gap-43_protein / Gardening / Gardens / Gasoline / Gastrectomy / Gastric_bypass / Gastric_emptying / Gastroenteritis / Gastroenterology / Gastroesophageal_reflux / Gastrointestinal_microbiome / Gastrointestinal_motility / 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Exercise

A fluorescent aptasensor for deoxynivalenol detection based on Nb.BbvCI-assisted targeted-responsive three-way junctions integrated DNA walking machine.

Deoxynivalenol (DON) contamination in cereals is a widespread issue with global implications, necessitating the development of efficient detection methods. Here, a fluorescent aptasensor integrating target-responsive DNA three-way junction (TWJ) and DNA walking machine was developed to detect DON. The DON-specific...

🗓️ 2024-12-06

📰 Publication: Food Chemistry

1-phosphatidylinositol_4-kinase / 2-acetylaminofluorene / 3'_untranslated_regions / 5-hydroxytryptophan / Abdominal_pain / Abdominoplasty / Abetalipoproteinemia / Absenteeism / Absorption / Academic_performance / Accidental_falls / Accounting / Acetone / Acetylcholine / Achondroplasia / Acid_phosphatase / Acidosis,_renal_tubular / Acinetobacter_baumannii / Acitretin / Aconitic_acid / Acoustics / Acquired_immunodeficiency_syndrome / Acrylonitrile / Acute_kidney_injury / Acute_lung_injury / Adenocarcinoma / Adenocarcinoma_of_lung / Adenocarcinoma,_mucinous / Adenoidectomy / Adenoids / Adenomyosis / Adenosine / Adhesives / Adipocytes / Adipokines / Adipose_tissue / Adolescent / Adoptive_transfer / Adrenal_cortex_hormones / Adrenalectomy / Adrenocorticotropic_hormone / Aftercare / Agaricales / Aged / Ageism / Aggrecans / Aggression / Agricultural_irrigation / Agriculture / Aids-related_complex / Air_pollution / Airway_management / Alanine / Alcohol_drinking / Alcoholics / Alcoholism / Alginates / Algorithms / Alkaloids / Alkynes / Alleles / Allergens / Allografts / Alloys / Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic_acid / Alpha-fetoproteins / Alphapapillomavirus / Altitude / Alzheimer_disease / Amaranth_dye / Ambulances / Amino_acid_substitution / Amino_acids / Aminoglycosides / Amlodipine / Amnion / Amoxicillin / Amplifiers,_electronic / Amputation,_surgical / Amputees / Amygdala / Amyloid / Amyotrophic_lateral_sclerosis / Analgesics / Anaphylaxis / Anastomotic_leak / Anatomy / Androgens / Anemia / Anemia,_iron-deficiency / Anesthesia / Anesthesiology / Anesthetics / Aneurysm,_false / Angina_pectoris / Angina,_unstable / Angiogenesis / Angiogenesis_inhibitors / Angiotensins / Anion_exchange_resins / Ankle / Anoikis / Anorexia_nervosa / Anterior_chamber / Anthocyanins / Anthracyclines / Anthropometry / Anti-inflammatory_agents,_non-steroidal / Antibodies,_bispecific / Antibodies,_monoclonal / Anticoagulants / Anticonvulsants / Antifibrinolytic_agents / Antihypertensive_agents / Antimicrobial_stewardship / Antineoplastic_agents / Antioxidants / Antiphospholipid_syndrome / Antipsychotic_agents / Antitubercular_agents / Antiviral_agents / Aorta / Aortic_aneurysm / Aortic_aneurysm,_abdominal / Aortic_dissection / Aortic_valve / Aphasia / Aphasia,_primary_progressive / Apicoplasts / Apolipoproteins / Apoptosis / Apoptosis_regulatory_proteins / Appendiceal_neoplasms / Appendicitis / Appendix / Appetite / Arboviruses / Arenavirus / Arginine / Arrhythmias,_cardiac / Arteriovenous_malformations / Arthralgia / Arthritis / Arthritis,_rheumatoid / Arthroplasty / Arthroplasty,_replacement,_knee / Artificial_intelligence / Artificially_sweetened_beverages / Ascorbic_acid / Aspartate_aminotransferases / Aspartic_acid / Aspergillosis / Aspergillosis,_allergic_bronchopulmonary / Asthenozoospermia / Astrocytes / Astrocytoma / Astronauts / Ataxia / Ataxia_telangiectasia / Atherectomy / Atherosclerosis / Athletes / Atrasentan / Atrial_fibrillation / Atrophy / Attention_deficit_disorder_with_hyperactivity / Attentional_bias / Attitude_to_health / Audiology / Augmented_reality / Authorship / Autism_spectrum_disorder / Autistic_disorder / Autoantibodies / Autoimmune_diseases / Autophagy / Autopsy / Axial_spondyloarthritis / Axons / B-lymphocytes / Back_pain / Bacterial_adhesion / Bacteriocins / Bacteriophages / Balantidiasis / Bariatric_surgery / Bartonella / Base_sequence / Basement_membrane / Basophils / Beds / Begomovirus / Behcet_syndrome / Benzene / Benzimidazoles / Benzocaine / Bevacizumab / Bezafibrate / Bibliometrics / Bicuspid / Bicuspid_aortic_valve_disease / Bilirubin / Biochemistry / Biocompatible_materials / Biodiversity / Biofilms / Biogenic_amines / Biological_availability / Biological_factors / Biological_monitoring / Biological_oxygen_demand_analysis / Biological_therapy / Biomarkers / Biomass / Biomedical_research / Biomimetics / Biophysics / Biopolymers / Biopsy / Biosimilar_pharmaceuticals / Biostatistics / Biotechnology / Birth_rate / Birth_weight / Blepharoplasty / Blindness / Blister / BLOOD / Blood_circulation / Blood_component_removal / Blood_culture / Blood_glucose / Blood_platelet_disorders / Blood_platelets / Blood_pressure / Blood_urea_nitrogen / Blood_vessels / Blood_volume / Blood-brain_barrier / Bocavirus / Body_composition / Body_mass_index / Body_size / Body_temperature / Body_weight / Bone_conduction / Bone_density / Bone_regeneration / Bone_transplantation / Botulinum_toxins / Brachytherapy / Brain_diseases / Brain_injuries / Brain_injuries,_traumatic / Brain_neoplasms / Bread / Breast_diseases / Breast_feeding / Breast_implants / Breast_neoplasms / Breeding / Bronchiectasis / Bronchiolitis_obliterans_syndrome / Bronchoalveolar_lavage / Bronchopulmonary_dysplasia / Bronchoscopy / Bruxism / Buffers / Burns / Butter / Calcinosis / Calcitonin / Calcium / Calcium_signaling / Camptothecin / Cancer_pain / Candy / Cannabidiol / Cannula / Capillaries / Capsaicin / Capsules / 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Muscle

Skeletal Muscle P MR Spectroscopy Surpasses CT in Predicting Patient Survival After Liver Transplantation.

Skeletal muscle alterations are associated with higher mortality and morbidity in patients with liver cirrhosis. Assessing these changes seems to be a promising method for identifying patients at a high risk of poor outcomes following liver transplantation (LT). This is...

🗓️ 2024-11-23

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

BLOOD / Blood_cells / cachexia / CELLS / Erythrocyte_transfusion / Erythrocytes / liver / Liver_transplantation / Muscle,_skeletal / muscles / Sarcopenia

Muscle

Heat exposure promotes sarcopenia via gut microbiota-derived metabolites.

The unprecedented rise in global ambient temperatures in the last decade has significantly impacted human health, yet how heat exposure affects the development of sarcopenia remains enigmatic. Here, we demonstrate that chronic heat exposure induces skeletal muscle volume loss, leading...

🗓️ 2024-10-29

📰 Publication: Aging Cell

BLOOD / Gastrointestinal_microbiome / Microbiota / Muscle,_skeletal / muscles / Sarcopenia / TEMPERATURE

Cachexia

Adenosine A2B receptor activation regulates the balance between T helper 17 cells and regulatory T cells, and inhibits regulatory T cells exhaustion in experimental autoimmune myositis.

Idiopathic inflammatory myopathy (IIM) is a systemic autoimmune disease characterized by skeletal muscle involvement. This study aimed to investigate the role of adenosine receptor signalling pathways in the development of experimental autoimmune myositis (EAM). An ecto-5'-nucleotidase (CD73) inhibitor, adenosine receptor...

🗓️ 2024-09-16

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

5'-nucleotidase / BLOOD / CELLS / Muscle,Skeletal / muscles / Musculardiseases / Myositis / Pharmaceuticalvehicles / Purinergicp1receptoragonists / Receptor,adenosinea2b / Receptors,purinergicp1 / Sarcopenia / SERUM / T-lymphocytes,regulatory / Th17cells

Cachexia

Increased Expression of Proinflammatory Genes in Peripheral Blood Cells Is Associated with Cardiac Cachexia in Patients with Heart Failure with Reduced Ejection Fraction.

: Cardiac cachexia (CC) in chronic heart failure with reduced ejection fraction (HFrEF) is characterized by catabolism and inflammation predicting poor prognosis. Levels of responsible transcription factors like signal transducer and activator of transcription (STAT)1, STAT3, suppressor of cytokine signaling...

🗓️ 2024-01-27

Biopsy / BLOOD / Bloodcells / Genes / heart / Heartfailure

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The Journal of Cachexia, Sarcopenia & Muscle ⟶

BLOOD

Blood-Brain Barrier-Penetrating Nanocarriers Enable Microglial-Specific Drug Delivery in Hypothalamic Neuroinflammation.

Detrimental Effects of β2-Microglobulin on Muscle Metabolism: Evidence From In Vitro, Animal and Human Research.

Device-Measured Physical Activity, Sedentary Behaviour and Risk of Chronic Kidney Diseases Across Levels of Grip Strength.

The Effect of Anti-Activin Receptor Type IIA and Type IIB Antibody on Muscle, Bone and Blood in Healthy and Osteosarcopenic Mice.

Electrospun microfibers to enhance nutrient supply in bioinks and 3D-bioprinted tissue precursors.

A fluorescent aptasensor for deoxynivalenol detection based on Nb.BbvCI-assisted targeted-responsive three-way junctions integrated DNA walking machine.

Skeletal Muscle P MR Spectroscopy Surpasses CT in Predicting Patient Survival After Liver Transplantation.

Heat exposure promotes sarcopenia via gut microbiota-derived metabolites.

Adenosine A2B receptor activation regulates the balance between T helper 17 cells and regulatory T cells, and inhibits regulatory T cells exhaustion in experimental autoimmune myositis.

Increased Expression of Proinflammatory Genes in Peripheral Blood Cells Is Associated with Cardiac Cachexia in Patients with Heart Failure with Reduced Ejection Fraction.

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