Aged

Muscle

Norharmane prevents muscle aging via activation of SKN-1/NRF2 stress response pathways.

Sarcopenia, the age-related decline in muscle mass and function, is a significant contributor to increased frailty and mortality in the elderly. Currently, no FDA-approved treatment exists for sarcopenia. Here, we identified norharmane (NR), a β-carboline alkaloid, as a potential therapeutic...

🗓️ 2025-01-27

📰 Publication: Redox Biology

Aged / Aging / CELLS / Cellular_senescence / Genes / muscles / Myoblasts / Sarcopenia / Stress,_physiological / therapeutics

Sarcopenia

Effects of digital-based interventions on the outcomes of the eligibility criteria for sarcopenia in healthy older adults: A systematic review and meta-analysis.

While the digital-based interventions targeting older adults to prevent age-related health problems such as sarcopenia have grown rapidly in recent years, there are no meta-analyses indicating synthesized pooled estimates. To examine the effects of digital-based interventions on sarcopenia-related measures, including...

🗓️ 2025-01-13

📰 Publication: Ageing Research Reviews

Aged / Hand_strength / Randomized_controlled_trials_as_topic

Cachexia

Prevalence of Cachexia and Outcomes in Patients With Chronic Diseases: A National Database Analysis of 5 484 103 Hospitalisations.

Cachexia is a frequent companion of chronic diseases and a well-established predictor of poor patient performance and outcome. Since cachexia as a discharge diagnosis is not much investigated, we aimed to investigate prevalence of cachexia in hospitalised patients and their...

🗓️ 2025-02-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Aged / Aged,_80_and_over / Chronic_disease / Databases,_factual / Hospitalization / PREVALENCE / Retrospective_studies

Cachexia

Weight and Blood-Based Markers of Cachexia Predict Disability, Hospitalization and Worse Survival in Cancer Immunotherapy Patients.

Cancer-associated cachexia can inhibit immune checkpoint inhibitor (ICI) therapy efficacy. Cachexia's effect on ICI therapy has not been studied in large cohorts of cancer patients aside from lung cancer. We studied associations between real-world routinely collected clinical cachexia markers and...

🗓️ 2025-02-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Aged / Biomarkers / Hospitalization / Immunotherapy / neoplasms / Prognosis / Retrospective_studies

Muscle

Melatonin Ameliorates Age-Related Sarcopenia via the Gut-Muscle Axis Mediated by Serum Lipopolysaccharide and Metabolites.

Sarcopenia affects the quality of life and increases adverse outcomes in the elderly. However, as a potential safe and effective remedy to many age-related disorders, little is known about the protective effect of melatonin against sarcopenia, especially the underlying mechanisms...

🗓️ 2025-02-01

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Aged / Apoptosis / Caspase_8 / Caspases / Gastrointestinal_microbiome / Lipopolysaccharides / Mediation_analysis / Melatonin / Microbiota / Muscle_strength / Muscle,_skeletal / muscles / Sarcopenia / SERUM

Muscle

Risk of Sarcopenia Following Long-Term Statin Use in Community-Dwelling Middle-Aged and Older Adults in Japan.

Inconsistent results have been reported concerning the association between statin administration and muscle health, specifically its potential to increase the risk of sarcopenia. Given the widespread long-term use of statins among the elderly population, the exploration of this association remains...

🗓️ 2024-12-16

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Aged / cachexia / Hydroxymethylglutaryl-coa_reductase_inhibitors / Muscle_strength / Muscle,_skeletal / muscles / Propensity_score / Sarcopenia / Sex

Exercise

Electrospun microfibers to enhance nutrient supply in bioinks and 3D-bioprinted tissue precursors.

3D-bioprinting is a promising technique to mimic the complex anatomy of natural tissues, as it comprises a precise and gentle way of placing bioinks containing cells and hydrogel. Although hydrogels expose an ideal growth environment due to their extracellular matrix...

🗓️ 2024-12-11

📰 Publication: Biofabrication

2,2'-dipyridyl / 3-iodobenzylguanidine / 3,3'-diaminobenzidine / 3'_untranslated_regions / 5-methylcytosine / 5'_untranslated_regions / Abattoirs / Abdominal_muscles / Abdominal_neoplasms / Abdominal_pain / Abdominoplasty / Abortion,_spontaneous / Absenteeism / Absorption / Academic_medical_centers / Academic_performance / Accidental_falls / Accidents / Accounting / Acepromazine / Acetaldehyde / Acetals / Acetates / Acetylcholine / Acetylcholinesterase / Acetylcysteine / Acetylene / Acetylglucosamine / Acetyltransferases / Achievement / Acid_ceramidase / Acid_sensing_ion_channels / Acid-base_equilibrium / Acidosis / Acinetobacter / Acinetobacter_baumannii / Acne_vulgaris / Acoustics / Acquired_immunodeficiency_syndrome / Acromegaly / Acrylamide / Actins / Action_potentials / Activities_of_daily_living / Acute_care_surgery / Acute_coronary_syndrome / Acute_kidney_injury / Acute_lung_injury / Acyltransferases / Adaptation,_physiological / Adenocarcinoma_of_lung / Adenoma / Adenoma,_pleomorphic / Adenomyosis / Adenosine / Adhesives / Adipocytes / Adipocytes,_brown / Adipocytes,_white / Adipogenesis / Adiponectin / Adipose_tissue / Adiposity / Administration,_intranasal / Administration,_oral / Adolescent / Adrenal_cortex_hormones / Adrenocorticotropic_hormone / Adult_stem_cells / Advance_care_planning / Adverse_childhood_experiences / Advertising / Aeromonas_veronii / Aerosols / Aflatoxin_m1 / Aflatoxins / African_swine_fever / Aftercare / Agar / Agaricales / Age_distribution / Aged / Agent_orange / Aggregatibacter / Aggregatibacter_aphrophilus / Aggression / Aging,_premature / Agranulocytosis / Agricultural_irrigation / Agriculture / Agrochemicals / Aids-related_complex / Air_pollution / Alanine / Alcohol_drinking / Alcoholics / Aldehydes / Aldosterone / Alendronate / Alginates / Algorithms / Alkaline_phosphatase / Alkalosis / Alkanesulfonates / Alkynes / Alleles / Allergens / Allografts / Allopurinol / Alloys / Alopecia / Alopecia_areata / Alpha_1-antitrypsin / Alpha_1-antitrypsin_deficiency / Alpha-glucosidases / Alpha-linolenic_acid / Alpha-synuclein / Alphapapillomavirus / Altitude / Alzheimer_disease / Amanita / Ambulances / Ambulatory_care / Ambulatory_care_facilities / Amikacin / Amine_oxidase_(copper-containing) / Amines / Amino_acid_sequence / Amino_acid_substitution / Amino_acids / Amino_acids,_branched-chain / Amino_acids,_sulfur / Amino_alcohols / Aminolevulinic_acid / Amlodipine / Amoxicillin / Amphetamines / Amphotericin_b / Amplifiers,_electronic / Amputation,_surgical / Amputees / Amygdala / Amyloid / Amyloidosis / Amylopectin / Amyotrophic_lateral_sclerosis / Analgesia / Analgesics / Analysis_of_variance / Anaphylaxis / Anastomotic_leak / Anemia / Anemia,_aplastic / Anemia,_iron-deficiency / Anemia,_sickle_cell / Anesthesia / Anesthesia,_conduction / Anesthesia,_epidural / Anesthesia,_intravenous / Anesthesia,_local / Anesthesia,_obstetrical / Anesthesiologists / Anesthesiology / Anesthetics / Anesthetics,_local / Aneuploidy / Aneurysm,_false / Anger / Angina_pectoris / Angioedema / Angioedemas,_hereditary / Angiopoietins / Angiotensins / Anhydrides / Aniline_compounds / Animal_communication / Anisometropia / Ankle / Ankyloglossia / Ankylosis / Annexin_a5 / Annexins / Anoikis / Anosmia / Anterior_chamber / Anterior_cruciate_ligament_injuries / Anthelmintics / Anthocyanins / Anthracyclines / Anthropology / Anthropometry / Anti-bacterial_agents / Anti-inflammatory_agents,_non-steroidal / Antibiotic_prophylaxis / Antibodies / Antibodies,_antineutrophil_cytoplasmic / Antibodies,_blocking / Antibodies,_monoclonal / Antibodies,_neutralizing / Antibody_formation / Anticoagulants / Antidepressive_agents / Antigen-presenting_cells / Antigens,_nuclear / Antigens,_surface / Antihypertensive_agents / Antimicrobial_stewardship / Antineoplastic_agents / Antioxidants / Antiphospholipid_syndrome / Antipsychotic_agents / Antipyretics / Antiviral_agents / Anxiety_disorders / Aorta / Aortic_aneurysm / Aortic_aneurysm,_abdominal / Aortic_aneurysm,_thoracic / Aortic_aneurysm,_thoracoabdominal / Aortic_diseases / Aortic_dissection / Aortic_rupture / Aortic_valve / Aortic_valve_disease / Apathy / Apelin / Aphasia / Apigenin / Apolipoproteins / Apoprotein(a) / Apoptosis / Appendectomy / Appendicitis / Appendix / Appetite / Aquaculture / Aquatic_organisms / Arachnoiditis / Archaea / Archives / Area_under_curve / Arginine / Argon_plasma_coagulation / Aristolochic_acids / Arrestin / Arrhythmias,_cardiac / Arterial_occlusive_diseases / Arterioles / Arteriovenous_fistula / Arteriovenous_malformations / Arterivirus / Arthritis,_psoriatic / Arthritis,_reactive / Arthritis,_rheumatoid / Arthrodermataceae / Arthroplasty,_replacement,_knee / Arthroscopy / Artificial_intelligence / Artificial_limbs / Ascorbic_acid / Aspartate_aminotransferases / Aspartic_acid / Aspergillus / Aspergillus_niger / Aspirin / Asthma / Astigmatism / Astringents / Astrocytes / Astrocytoma / Ataxia / Atenolol / Atherosclerosis / Athletes / Athletic_performance / Atmosphere / Atorvastatin / Atrial_appendage / Atrial_fibrillation / Atrial_flutter / Atrophy / Attention_deficit_disorder_with_hyperactivity / Attentional_bias / Audiometry / Audiovisual_aids / Augmented_reality / Autism_spectrum_disorder / Autistic_disorder / Autoantigens / Autoimmune_diseases / Autoimmunity / Automation / Autophagosomes / Autophagy / Autopsy / Axenic_culture / Axial_spondyloarthritis / Axillary_vein / Axons / Azacitidine / Azathioprine / Azoospermia / Azospirillum / Azospirillum_brasilense / B-lymphocytes / Bacillus / Bacillus_amyloliquefaciens / Bacillus_subtilis / Back_pain / Bacterial_adhesion / Bacterial_infections / Bacterial_load / Bacteriocins / Bacteriophages / Bacteroides / Bacteroides_fragilis / Badnavirus / Bariatric_surgery / Bartonella / Bartonella_quintana / Basal_ganglia / Basal_nucleus_of_meynert / Basement_membrane / Basidiomycota / Basolateral_nuclear_complex / Beauty / Beckwith-wiedemann_syndrome / Beds / Begomovirus / Behavior_therapy / Behavior,_animal / Behavioral_symptoms / Benchmarking / Benserazide / Benzene / Benzocaine / Benzodiazepines / Benzyl_alcohol / Berberine / Beta-lactams / Betaine / Betaine-homocysteine_s-methyltransferase / Bevacizumab / Beverages / Bezafibrate / Bezoars / Bias / Bibliometrics / Bicuspid / Bicuspid_aortic_valve_disease / Bifidobacterium / Bifidobacterium_longum / Bile / Bile_ducts / Biliary_tract / Bilirubin / Binge-eating_disorder / Biocompatible_materials / Biodegradable_plastics / Biodegradation,_environmental / Biodiversity / Biofeedback,_psychology / Biofilms / Biological_assay / Biological_availability / Biological_science_disciplines / Biological_therapy / Biomarkers / Biomarkers,_tumor / Biomass / Biomedical_research / Biometry / Biomimetics / Bioprinting / Biosimilar_pharmaceuticals / Biosurveillance / Biotransformation / Bipolar_disorder / Birth_certificates / Birth_order / Birth_weight / Bleomycin / Blindness / BLOOD / Blood_cell_count / Blood_cells / Blood_circulation / Blood_coagulation_factors / Blood_component_removal / Blood_culture / Blood_donors / Blood_glucose / Blood_platelets / Blood_pressure / Blood_pressure_monitoring,_ambulatory / Blood_substitutes / Blood_transfusion,_intrauterine / Blood_urea_nitrogen / Blood_vessels / Blood_volume / Blotting,_western / Body_composition / Body_contouring / Body_image / Body_mass_index / Body_size / Body_weight / Bone_cements / Bone_cysts / Bone_diseases / Bone_marrow / Bone_neoplasms / Bone_regeneration / Bone_transplantation / Bony_callus / Borates / Botany / Botulinum_toxins / Botulinum_toxins,_type_a / Botulism / Bowen's_disease / Bradycardia / Bradykinin / Brain / Brain_diseases / Brain_injuries / Brain_injuries,_traumatic / Brain_ischemia / Brain_stem / Brain_stem_infarctions / Bread / Breast / Breast_cancer_lymphedema / Breast_feeding / Breast_neoplasms / Bronchiectasis / Bronchiolitis_obliterans_syndrome / Bronchitis / Bronchogenic_cyst / Bronchopulmonary_sequestration / Bronchoscopy / Brucella / Brucellosis / Brugada_syndrome / Budesonide / Buffers / Bulimia / Bundle-branch_block / Bupropion / Burning_mouth_syndrome / Burnout,_psychological / Burns / Butter / Butyrylcholinesterase / C-peptide / C-reactive_protein / Ca-19-9_antigen / cachexia / Caco-2_cells / Cadherins / Caffeine / Calcitonin_gene-related_peptide / Calcium / Calcium_channel_blockers / Calcium_channels / Calcium_signaling / Cancer_vaccines / Cancer-associated_cachexia / Cancer-associated_fibroblasts / Candidemia / Candidiasis / Candidiasis,_invasive / Candidiasis,_vulvovaginal / Cannabidiol / Cannula / Capacity_building / Capillaries / Capsaicin / Capsid / Capsules / Car-t_cell / Carbamazepine / Carbapenems / Carbidopa / Carbohydrates / Carboxylic_acids / Carcinogenesis / Carcinogens / Carcinoid_tumor / Carcinoma_in_situ / Carcinoma,_basal_cell / Carcinoma,_hepatocellular / Carcinoma,_intraductal,_noninfiltrating / Carcinoma,_non-small-cell_lung / Carcinoma,_ovarian_epithelial / Carcinoma,_renal_cell / Carcinoma,_squamous_cell / Cardiac_catheters / Cardiac_output / Cardiac_rehabilitation / Cardiac_resynchronization_therapy / Cardiac_volume / Cardiology / Cardiomyopathy,_restrictive / Cardiopulmonary_bypass / Cardiopulmonary_resuscitation / Cardiotoxicity / Cardiovascular_diseases / Cardiovascular_system / Caregivers / Carotenoids / Carotid_arteries / Carotid_artery,_internal / Carrier_proteins / Case-control_studies / Caseins / Caspase_3 / Caspase_9 / Caspases / Castleman_disease / Castration / Catalase / Cataract / Catastrophization / Catechin / Catechol_o-methyltransferase / Catecholamines / Catenins / Catheter_ablation / Catheterization / Causality / Caveolins / Cecum / Cefazolin / Cefoperazone / Cefotaxime / Ceftazidime / Ceftriaxone / Celiac_disease / Cell_aggregation / Cell_biology / Cell_body / Cell_communication / Cell_count / Cell_culture_techniques / Cell_cycle / Cell_death / Cell_differentiation / Cell_fusion / Cell_line / Cell_membrane / Cell_proliferation / Cell_survival / Cell_transplantation / Cell_wall / Cell-free_nucleic_acids / CELLS / Cellular_senescence / Cellulose / Censuses / Centers_for_disease_control_and_prevention,_u.s. / Central_amygdaloid_nucleus / Central_nervous_system / Central_nervous_system_diseases / Central_nervous_system_sensitization / Central_venous_catheters / Centromere / Cephalosporins / Ceramics / Ceramidases / Ceramides / Cerebellar_ataxia / Cerebellum / Cerebral_arteries / Cerebral_cortex / Cerebral_hemorrhage / Cerebral_infarction / Cerebral_palsy / Cerebral_small_vessel_diseases / Cerebrospinal_fluid_leak / Cerebrospinal_fluid_rhinorrhea / Cerebrovascular_circulation / Cerebrovascular_disorders / Cervical_cord / Cervical_vertebrae / Cervix_uteri / Cesarean_section / Chagas_disease / Chaperonins / Charcot-marie-tooth_disease / Cheese / Chemical_safety / Chemistry,_clinical / Chemokine_ccl11 / Chemokine_ccl22 / Chemokine_cx3cl1 / Chemokine_cxcl12 / Chemokines / Chemokines,_cxc / Chemoprevention / Chemoradiotherapy / Chemotherapy,_adjuvant / Chest_pain / Chick_embryo / Chickenpox / Chikungunya_virus / Child_abuse,_sexual / Child_custody / Child_development / Child_health / Child_health_services / Child,_hospitalized / Child,_preschool / Chimera / Chimerism / Chitin / Chitosan / Chlamydia / Chloramphenicol / Chlorogenic_acid / Chlorophyll / Chlorophyll_a / Chloroplasts / Chlortetracycline / Cholangiocarcinoma / Cholangiography / Cholangitis / Cholecalciferol / Cholecystectomy / Cholecystitis / Cholecystitis,_acute / Choledocholithiasis / Cholera / Cholestasis / Cholestasis,_intrahepatic / Cholesterol / Cholesterol_esters / Cholesterol,_hdl / Cholesterol,_ldl / Cholinergic_agents / Chondrocytes / Chondrogenesis / Chondroitin / Chondroitin_sulfates / Chordoma / Chorea / Chorioamnionitis / Chromatin / Chromatin_immunoprecipitation / Chromogranin_a / Chromogranins / Chromosome_aberrations / Chronic_disease / Chronic_pain / Chylothorax / Chylous_ascites / Cicatrix / Cilia / Ciprofloxacin / Circadian_clocks / Circovirus / Circulating_microrna / Circulating_tumor_dna / Citalopram / Citizen_science / Citric_acid / Citrinin / Citrobacter / Citrobacter_rodentium / Citrulline / Cladribine / Classical_swine_fever / Clathrin / Clay / Climacteric / Climate / Clinical_alarms / Clinical_decision-making / Clinical_laboratory_techniques / Clitoris / Clobazam / Clone_cells / Clonidine / Clostridioides / Clostridioides_difficile / Clostridium / Cloud_computing / Clozapine / Cluster_analysis / Clustered_regularly_interspaced_short_palindromic_repeats / Clutch_size / Coagulase / Coal / Coal_industry / Coccidioidomycosis / Cochlear_implants / Cochlear_nucleus / Coconut_oil / Codon / Coffee / Cognition_disorders / Cognitive_behavioral_therapy / Cognitive_dissonance / Cognitive_dysfunction / Cognitive_restructuring / Cognitive_training / Cohort_studies / Coinfection / Colchicine / Cold_temperature / Colectomy / Colic / Colistin / Colitis / Colitis,_ulcerative / Collagen / Collagen_type_i / Collagen_type_ii / Collagenases / Collectins / Colletotrichum / Collodion / COLON / Colon,_ascending / Colon,_sigmoid / Colon,_transverse / Colonic_neoplasms / Colonoscopy / Colony-stimulating_factors / Colorectal_neoplasms / Colorectal_surgery / Colostomy / Colposcopy / Coma,_post-head_injury / Commerce / Common_variable_immunodeficiency / Communicable_diseases / Communicable_diseases,_emerging / Communication / Community_health_workers / Community_participation / Comorbidity / Compartment_syndromes / Complement_activation / Complement_c1_inhibitor_protein / Complement_c1q / Complement_c3a / Complement_inactivating_agents / Complement_system_proteins / Complementary_therapies / Complex_regional_pain_syndromes / Composite_resins / Composting / Computational_chemistry / Computed_tomography_angiography / Computers / Conditioning,_psychological / Confidence_intervals / Confined_spaces / Conflict_of_interest / Conflict,_psychological / Congo_red / Connective_tissue / Consciousness / Consent_forms / Conservative_treatment / Constipation / Contact_lenses / Continuous_glucose_monitoring / Contraceptive_agents / Contracture / Contraindications / Contusions / Conversion_disorder / Conversion_to_open_surgery / Cooperative_behavior / Coral_reefs / Cornea / Coronary_artery_bypass / Coronary_artery_disease / Coronary_disease / Coronary_sinus / Coronavirus_infections / Cost_of_illness / Cost_savings / Coumarins / Covid-19 / Covid-19_testing / Cranial_nerves / Craniopharyngioma / Craniotomy / Craving / Creatine / Creativity / Creutzfeldt-jakob_syndrome / Criminal_law / Critical_care / Critical_illness / Critical_period,_psychological / Crohn_disease / Cronobacter / Cronobacter_sakazakii / Crop_production / Cross_infection / Cross-over_studies / Cross-sectional_studies / Crowdsourcing / Crowns / Cryogels / Cryoglobulinemia / Cryoglobulins / Cryopreservation / 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Diet,_healthy / Diet,_ketogenic / Diet,_mediterranean / Diet,_vegan / Diet,_vegetarian / Dietary_exposure / Dietary_fats / Dietary_fiber / Dietary_patterns / Dietary_supplements / Diethylhexyl_phthalate / Diffusion_tensor_imaging / Digeorge_syndrome / Digestion / Digital_health / Digital_technology / Digital_therapeutics / Diglycerides / Dioxins / Dipeptidyl_peptidase_4 / Dipeptidyl-peptidase_iv_inhibitors / Diphosphonates / Disabled_children / Disabled_persons / Disaster_medicine / Discriminant_analysis / Disease_management / Disease_progression / Disease_transmission,_infectious / Disease-free_survival / Disinfectants / Diskectomy / Displacement,_psychological / Dissection,_thoracic_aorta / Disseminated_intravascular_coagulation / Distemper_virus,_canine / Disulfides / Disulfiram / Diuretics / Diverticular_diseases / Diverticulitis / Diverticulum / Diving / Dizziness / Dna_damage / Dna_glycosylases / Dna_gyrase / Dna_methylation / Dna_nucleotidylexotransferase / Dna_replication / 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/ Eating / Ebstein_anomaly / Echocardiography / Ecological_momentary_assessment / Ecology / Economics / Economics,_behavioral / Ecosystem / Ectopia_lentis / Ectropion / Eczema / Edaravone / Edible_grain / Education,_medical / Education,_medical,_continuing / Education,_medical,_undergraduate / Egg_yolk / Eggs / Eicosapentaenoic_acid / Ejaculation / Elasticity_imaging_techniques / Elastomers / Electric_power_supplies / Electroacupuncture / Electrocardiography / Electroconvulsive_therapy / Electrodes / Electroencephalography / Electronic_health_records / Electronic_medical_record / Electronic_nicotine_delivery_systems / Electrophysiology / Electroporation / Embolism,_fat / Embryo_transfer / Embryonic_development / Emergencies / Emergency_medical_services / Emergency_medicine / Emergency_responders / Emergency_service,_hospital / Emergency_shelter / Emotional_regulation / Emotions / Employment / Empowerment / Emulsions / Endarterectomy / Endocannabinoids / Endocarditis / Endocytosis / Endodontics / Endoleak / Endometrial_neoplasms / Endometriosis / Endopeptidases / Endophthalmitis / Endophytes / Endoplasmic_reticulum / Endoplasmic_reticulum_stress / Endoscopes / Endoscopic_mucosal_resection / Endoscopy / Endoscopy,_gastrointestinal / Endothelial_cells / Endothelial_growth_factors / Endothelin_receptor_antagonists / Endothelin-1 / Endothelium / Endotoxins / Endurance_training / Enema / Energy_drinks / Energy_intake / Enhanced_recovery_after_surgery / Enhancer_elements,_genetic / Enteral_nutrition / Enterobacter / Enterococcus / Enterococcus_faecium / Enteropathogenic_escherichia_coli / Enterotoxigenic_escherichia_coli / Enterotoxins / Enterovirus / Environment_design / Environmental_health / Environmental_monitoring / Environmental_policy / Environmental_pollutants / Environmental_pollution / Enzyme-linked_immunosorbent_assay / Enzymes / Eosinophilia / Eosinophils / Ependymoma / Epidemics / Epidemiologic_studies / epidemiology / Epididymis / Epigenome / Epiglottis / 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Protein_isoforms / Protein_kinases / Protein_phosphatase_1 / Protein_processing,_post-translational / Protein_serine-threonine_kinases / Protein-tyrosine_kinases / Proteogenomics / Proteome / Proteomics / Prothrombin / Prothrombin_time / Proton_pump_inhibitors / Proton_pumps / Proton_therapy / Pruritus / Pseudogenes / Pseudomonas / Pseudomonas_aeruginosa / Pseudomonas_stutzeri / Pseudouridine / Psoriasis / Psychiatrists / Psychological_distress / Psychological_well-being / Psychology,_positive / Psychometrics / Psychosocial_intervention / Psychotherapy / Psychotic_disorders / Psychotropic_drugs / Public_health / Public_health_surveillance / Public_sector / Pulmonary_arterial_hypertension / Pulmonary_disease,_chronic_obstructive / Pulmonary_embolism / Pulmonary_fibrosis / Pulmonary_surfactant-associated_protein_a / Pulmonary_valve / Pulpectomy / Pulpotomy / Pulse / Punctures / Punishment / Pupa / Pupil / Purpura / Purpura,_thrombocytopenic / Putamen / Pyoderma / Pyoderma_gangrenosum / 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A fluorescent aptasensor for deoxynivalenol detection based on Nb.BbvCI-assisted targeted-responsive three-way junctions integrated DNA walking machine.

Deoxynivalenol (DON) contamination in cereals is a widespread issue with global implications, necessitating the development of efficient detection methods. Here, a fluorescent aptasensor integrating target-responsive DNA three-way junction (TWJ) and DNA walking machine was developed to detect DON. The DON-specific...

🗓️ 2024-12-06

📰 Publication: Food Chemistry

1-phosphatidylinositol_4-kinase / 2-acetylaminofluorene / 3'_untranslated_regions / 5-hydroxytryptophan / Abdominal_pain / Abdominoplasty / Abetalipoproteinemia / Absenteeism / Absorption / Academic_performance / Accidental_falls / Accounting / Acetone / Acetylcholine / Achondroplasia / Acid_phosphatase / Acidosis,_renal_tubular / Acinetobacter_baumannii / Acitretin / Aconitic_acid / Acoustics / Acquired_immunodeficiency_syndrome / Acrylonitrile / Acute_kidney_injury / Acute_lung_injury / Adenocarcinoma / Adenocarcinoma_of_lung / Adenocarcinoma,_mucinous / Adenoidectomy / Adenoids / Adenomyosis / Adenosine / Adhesives / Adipocytes / Adipokines / Adipose_tissue / Adolescent / Adoptive_transfer / Adrenal_cortex_hormones / Adrenalectomy / Adrenocorticotropic_hormone / Aftercare / Agaricales / Aged / Ageism / Aggrecans / Aggression / Agricultural_irrigation / Agriculture / Aids-related_complex / Air_pollution / Airway_management / Alanine / Alcohol_drinking / Alcoholics / Alcoholism / Alginates / Algorithms / Alkaloids / Alkynes / Alleles / Allergens / Allografts / Alloys / Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic_acid / Alpha-fetoproteins / Alphapapillomavirus / Altitude / Alzheimer_disease / Amaranth_dye / Ambulances / Amino_acid_substitution / Amino_acids / Aminoglycosides / Amlodipine / Amnion / Amoxicillin / Amplifiers,_electronic / Amputation,_surgical / Amputees / Amygdala / Amyloid / Amyotrophic_lateral_sclerosis / Analgesics / Anaphylaxis / Anastomotic_leak / Anatomy / Androgens / Anemia / Anemia,_iron-deficiency / Anesthesia / Anesthesiology / Anesthetics / Aneurysm,_false / Angina_pectoris / Angina,_unstable / Angiogenesis / Angiogenesis_inhibitors / Angiotensins / Anion_exchange_resins / Ankle / Anoikis / Anorexia_nervosa / Anterior_chamber / Anthocyanins / Anthracyclines / Anthropometry / Anti-inflammatory_agents,_non-steroidal / Antibodies,_bispecific / Antibodies,_monoclonal / Anticoagulants / Anticonvulsants / Antifibrinolytic_agents / Antihypertensive_agents / Antimicrobial_stewardship / Antineoplastic_agents / Antioxidants / Antiphospholipid_syndrome / Antipsychotic_agents / Antitubercular_agents / Antiviral_agents / Aorta / Aortic_aneurysm / Aortic_aneurysm,_abdominal / Aortic_dissection / Aortic_valve / Aphasia / Aphasia,_primary_progressive / Apicoplasts / Apolipoproteins / Apoptosis / Apoptosis_regulatory_proteins / Appendiceal_neoplasms / Appendicitis / Appendix / Appetite / Arboviruses / Arenavirus / Arginine / Arrhythmias,_cardiac / Arteriovenous_malformations / Arthralgia / Arthritis / Arthritis,_rheumatoid / Arthroplasty / Arthroplasty,_replacement,_knee / Artificial_intelligence / Artificially_sweetened_beverages / Ascorbic_acid / Aspartate_aminotransferases / Aspartic_acid / Aspergillosis / Aspergillosis,_allergic_bronchopulmonary / Asthenozoospermia / Astrocytes / Astrocytoma / Astronauts / Ataxia / Ataxia_telangiectasia / Atherectomy / Atherosclerosis / Athletes / Atrasentan / Atrial_fibrillation / Atrophy / Attention_deficit_disorder_with_hyperactivity / Attentional_bias / Attitude_to_health / Audiology / Augmented_reality / Authorship / Autism_spectrum_disorder / Autistic_disorder / Autoantibodies / Autoimmune_diseases / Autophagy / Autopsy / Axial_spondyloarthritis / Axons / B-lymphocytes / Back_pain / Bacterial_adhesion / Bacteriocins / Bacteriophages / Balantidiasis / Bariatric_surgery / Bartonella / Base_sequence / Basement_membrane / Basophils / Beds / Begomovirus / Behcet_syndrome / Benzene / Benzimidazoles / Benzocaine / Bevacizumab / Bezafibrate / Bibliometrics / Bicuspid / Bicuspid_aortic_valve_disease / Bilirubin / Biochemistry / Biocompatible_materials / Biodiversity / Biofilms / Biogenic_amines / Biological_availability / Biological_factors / Biological_monitoring / Biological_oxygen_demand_analysis / Biological_therapy / Biomarkers / Biomass / Biomedical_research / Biomimetics / Biophysics / Biopolymers / Biopsy / Biosimilar_pharmaceuticals / Biostatistics / Biotechnology / Birth_rate / Birth_weight / Blepharoplasty / Blindness / Blister / BLOOD / Blood_circulation / Blood_component_removal / Blood_culture / Blood_glucose / Blood_platelet_disorders / Blood_platelets / Blood_pressure / Blood_urea_nitrogen / Blood_vessels / Blood_volume / Blood-brain_barrier / Bocavirus / Body_composition / Body_mass_index / Body_size / Body_temperature / Body_weight / Bone_conduction / Bone_density / Bone_regeneration / Bone_transplantation / Botulinum_toxins / Brachytherapy / Brain_diseases / Brain_injuries / Brain_injuries,_traumatic / Brain_neoplasms / Bread / Breast_diseases / Breast_feeding / Breast_implants / Breast_neoplasms / Breeding / Bronchiectasis / Bronchiolitis_obliterans_syndrome / Bronchoalveolar_lavage / Bronchopulmonary_dysplasia / Bronchoscopy / Bruxism / Buffers / Burns / Butter / Calcinosis / Calcitonin / Calcium / Calcium_signaling / Camptothecin / Cancer_pain / Candy / Cannabidiol / Cannula / Capillaries / Capsaicin / Capsules / 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Lysophosphatidylcholines / Lysosomes / Machine_learning / Macrophages / Macrophages,_alveolar / Magnetic_resonance_imaging / Maintenance / Malnutrition / Mammaplasty / Mannans / Mannitol / Mannose-binding_lectin / Mannosyltransferases / Margins_of_excision / Marijuana_use / Marketing / Masculinity / Masks / Mast_cells / Mastitis / Mastitis,_bovine / Mastoiditis / Maternal_mortality / Mathematics / Meals / Meat / Mechanistic_target_of_rapamycin_complex_1 / Medial_tibial_stress_syndrome / Mediation_analysis / Medical_laboratory_science / Medical_marijuana / Medical_oncology / Medical_records / Medical_staff / Medical_waste / Medicare / Medication_adherence / Medication_errors / Medicine,_chinese_traditional / Medicine,_traditional / Meditation / Medulloblastoma / Melanins / Melanoma / Meloxicam / Membrane_proteins / Membranes / Memory / Menarche / Mendelian_randomization_analysis / Meninges / Meningioma / Meningitis / Menstruation / Mental_disorders / Mental_health / 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Monophenol_monooxygenase / Morphine / Morris_water_maze_test / MORTALITY / Mosaic_viruses / Mothers / Motivation / Motivational_interviewing / Motor_activity / Mouth / Mouth_neoplasms / Movement / Moxibustion / Mucosa-associated_lymphoid_tissue_lymphoma_translocation_1_protein / Mucous_membrane / Multimodal_imaging / Multiparametric_magnetic_resonance_imaging / Multiple_chronic_conditions / Multiple_myeloma / Multiple_sclerosis / Multiple_sclerosis,_relapsing-remitting / Multivariate_analysis / Muscle_cells / Muscle_spasticity / Muscle_strength / Muscle,_skeletal / Muscle,_smooth / muscles / Muscular_dystrophies / Muscular_dystrophy,_duchenne / Musculoskeletal_diseases / Musculoskeletal_system / Mutagenesis / Mutation / Mutation,_missense / Myalgia / Mycobacterium / Mycoses / Myeloid_cells / Myeloid-derived_suppressor_cells / Myoblasts / Myoblasts,_skeletal / Myocardial_infarction / Myocardium / Myocytes,_cardiac / Myocytes,_smooth_muscle / Myofibroblasts / Myokymia / Myoma / Myopia / 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Oligospermia / Olive_oil / Oncologists / Only_child / Oocyte_donation / Oocytes / Oogenesis / Operative_time / Ophthalmology / Optic_atrophy,_autosomal_dominant / Optic_disk / Optic_nerve / Optic_nerve_diseases / Optogenetics / Oral_hygiene / Oral_microbiome / Organelle_biogenesis / Organoids / Ornithine / Orthomyxoviridae / Orthopedics / Osseointegration / Osteoarthritis / Osteoblasts / Osteoclasts / Osteogenesis / Osteomalacia / Osteonecrosis / Osteoporosis / Osteosarcoma / Otitis / Otitis_media / Otolaryngology / Outpatients / Ovarian_neoplasms / Ovariectomy / Ovary / Overweight / Oviposition / Ovum / Ownership / Oxacillin / Oxaliplatin / Oxidants / Oxidative_stress / Oxidoreductases / Oximetry / Paclitaxel / Paecilomyces / Pain_management / Pain,_postoperative / Paint / Palate / Palliative_care / Palmitic_acid / Pancreas / Pancreatic_cyst / Pancreatic_pseudocyst / Pancreaticoduodenectomy / Pancreatitis / Pandemics / Papillomavirus_infections / Parabens / Paraffin / Paralysis / Paraneoplastic_syndromes / Parasites / Parasitology / Parent-child_relations / Parenteral_nutrition / Parenting / Parkinson_disease / Parotitis / Particulate_matter / Parturition / Pathologists / Patient_care / Patient_discharge / Patient_education_as_topic / Patient_participation / Patient_preference / Patient_reported_outcome_measures / Patient_safety / Patient_satisfaction / Pediatric_emergency_medicine / Pediatrics / Peer_review / Pelvic_pain / Pemphigoid,_bullous / Pemphigus / Penile_prosthesis / Penis / Peptide_hydrolases / Percutaneous_coronary_intervention / Periaqueductal_gray / Pericardium / Periodontitis / Perioperative_care / Peripheral_arterial_disease / Peroxidases / Peroxides / Personality / Perylene / Pesticides / Phaeohyphomycosis / Phagocytes / Phagocytosis / Pharmaceutical_preparations / Pharmaceutical_services / Pharmaceutical_vehicles / Pharmacists / Pharmacokinetics / Pharmacology / Pharmacology,_clinical / Pharmacovigilance / Pharmacy / Pharynx / Phenazines / 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Muscle

Reactive oxygen species in skeletal muscle injury, fatigue, regeneration and ageing: In memory of John Faulkner.

One of the most critical factors impacting healthspan in the elderly is the loss of muscle mass and function, clinically referred to as sarcopenia. Muscle atrophy and weakness lead to loss of mobility, increased risk of injury, metabolic changes and...

🗓️ 2024-11-27

📰 Publication: Free Radical Biology And Medicine

Aged / Atrophy / FATIGUE / Memory / Muscle,_skeletal / muscles / Oxidative_stress / Sarcopenia / Stress,_physiological

Cachexia

Body Composition and Incident High-Intensity Back Pain and/or High Disability: A 10-Year Prospective Population-Based Male Cohort.

Back pain poses a significant global burden, within which individuals with more severe symptoms consume higher healthcare expenses than those with lesser back pain. Whether measures of body composition predict high-intensity back pain and/or high-disability in population-based cohorts is unknown....

🗓️ 2024-11-24

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Aged / Back_pain / Body_composition / Body_mass_index / Pain / Sarcopenia / Weight_gain

Muscle

Concordance of Freehand 3D Ultrasound Muscle Measurements With Sarcopenia Parameters in a Geriatric Rehabilitation Ward.

Sarcopenia is a devastating disease for older adults, but it lacks accessible and reliable tools for measuring total appendicular skeletal muscle mass (ASMM). Two-dimensional muscle ultrasound (US) has been developed for its bedside clinical advantages and feasibility but lacks standardization...

🗓️ 2024-11-22

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Aged / Hand_strength / muscles / Rehabilitation / Research_design / Sarcopenia

Exercise

Impact of resistance training and chicken intake on vascular and muscle health in elderly women.

Resistance training is a well-known exercise therapy for preventing and improving lacks of muscle mass, strength, and quality with advances in age; however, its effects on arterial stiffness are not beneficial. Additionally, a higher intake of protein, which is an...

🗓️ 2024-11-21

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Aged / Angiotensins / Breast / cachexia / Diet / Food / muscles / Resistance_training / Sarcopenia

Frailty

New horizons in hospital-associated deconditioning: a global condition of body and mind.

Hospital-associated deconditioning is a broad term, which refers non-specifically to declines in any function of the body secondary to hospitalisation. Older people, particularly those living with frailty, are known to be at greatest risk. It has historically been most commonly...

🗓️ 2024-11-01

📰 Publication: Age And Ageing

Aged / Cognition / Frail_elderly / Geriatric_assessment / Hospitalization / Risk_factors / Sarcopenia

Frailty

Comment on 'Effects of Sarcopenia and Frailty on Postoperative Recovery in Elderly Patients: A Prospective Cohort Study' by Guo et al.

🗓️ 2024-10-21

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Aged / cachexia / Cohort_studies / Recycling / Sarcopenia

Muscle

Prognostic Value of Systemic Inflammation, Nutritional Status and Sarcopenia in Patients With Amyotrophic Lateral Sclerosis.

Nutritional status, systemic inflammatory responses and muscle mass are associated with the prognosis of patients with amyotrophic lateral sclerosis (ALS). However, the optimal biomarker for predicting prognosis remains unclear. This study aimed to identify the optimal indicators of survival among...

🗓️ 2024-10-24

📰 Publication: Journal Of Cachexia Sarcopenia And Muscle

Aged / Amyotrophic_lateral_sclerosis / cachexia / Creatinine / Cystatins / muscles / Nutritional_status / Prognosis / Sarcopenia / Sclerosis

Muscle

Nutritional strategies for improving sarcopenia outcomes in older adults: A narrative review.

Sarcopenia is characterized by a decline in muscle strength, generalized loss of skeletal muscle mass, and impaired physical performance, which are common outcomes used to screen, diagnose, and determine severity of sarcopenia in older adults. These outcomes are associated with...

🗓️ 2024-10-01

📰 Publication: Pharmacology Research & Perspectives

Aged / Amino_acids / Leucine / Muscle_proteins / muscles / Sarcopenia

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The Journal of Cachexia, Sarcopenia & Muscle ⟶

Aged

Norharmane prevents muscle aging via activation of SKN-1/NRF2 stress response pathways.

Effects of digital-based interventions on the outcomes of the eligibility criteria for sarcopenia in healthy older adults: A systematic review and meta-analysis.

Prevalence of Cachexia and Outcomes in Patients With Chronic Diseases: A National Database Analysis of 5 484 103 Hospitalisations.

Weight and Blood-Based Markers of Cachexia Predict Disability, Hospitalization and Worse Survival in Cancer Immunotherapy Patients.

Melatonin Ameliorates Age-Related Sarcopenia via the Gut-Muscle Axis Mediated by Serum Lipopolysaccharide and Metabolites.

Risk of Sarcopenia Following Long-Term Statin Use in Community-Dwelling Middle-Aged and Older Adults in Japan.

Electrospun microfibers to enhance nutrient supply in bioinks and 3D-bioprinted tissue precursors.

A fluorescent aptasensor for deoxynivalenol detection based on Nb.BbvCI-assisted targeted-responsive three-way junctions integrated DNA walking machine.

Reactive oxygen species in skeletal muscle injury, fatigue, regeneration and ageing: In memory of John Faulkner.

Body Composition and Incident High-Intensity Back Pain and/or High Disability: A 10-Year Prospective Population-Based Male Cohort.

Concordance of Freehand 3D Ultrasound Muscle Measurements With Sarcopenia Parameters in a Geriatric Rehabilitation Ward.

Impact of resistance training and chicken intake on vascular and muscle health in elderly women.

New horizons in hospital-associated deconditioning: a global condition of body and mind.

Comment on 'Effects of Sarcopenia and Frailty on Postoperative Recovery in Elderly Patients: A Prospective Cohort Study' by Guo et al.

Prognostic Value of Systemic Inflammation, Nutritional Status and Sarcopenia in Patients With Amyotrophic Lateral Sclerosis.

Nutritional strategies for improving sarcopenia outcomes in older adults: A narrative review.

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